SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yck'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)		 1yck PEPTIDOGLYCAN
RECOGNITION PROTEIN
(Homo
sapiens) 		4 / 5 THR A  48
LEU A  83
GLY A  79
TYR A  85
 None
 1.17A 1gtiF-1yckA:
undetectable		 1gtiF-1yckA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 1yck PEPTIDOGLYCAN
RECOGNITION PROTEIN
(Homo
sapiens) 		4 / 6 ASN A  75
GLY A  94
PRO A 103
SER A 105
 None
 1.00A 1n4fA-1yckA:
undetectable		 1n4fA-1yckA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 1yck PEPTIDOGLYCAN
RECOGNITION PROTEIN
(Homo
sapiens) 		5 / 12 GLY A 138
GLY A 134
LEU A 130
GLY A 129
PRO A 170
 None
 1.13A 1y4lA-1yckA:
undetectable		 1y4lA-1yckA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 1yck PEPTIDOGLYCAN
RECOGNITION PROTEIN
(Homo
sapiens) 		4 / 6 ILE A 124
ARG A 125
PRO A  49
SER A  51
 None
 1.48A 2qd3B-1yckA:
0.5		 2qd3B-1yckA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1yck PEPTIDOGLYCAN
RECOGNITION PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 162
ASP A 151
GLY A 148
ALA A 127
TYR A 172
 None
 1.18A 5kbwB-1yckA:
undetectable		 5kbwB-1yckA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1yck PEPTIDOGLYCAN
RECOGNITION PROTEIN
(Homo
sapiens) 		4 / 4 LEU A 162
GLY A 159
SER A 157
SER A  39
 None
 1.33A 5uunB-1yckA:
undetectable		 5uunB-1yckA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1yck PEPTIDOGLYCAN
RECOGNITION PROTEIN
(Homo
sapiens) 		4 / 5 ASP A  81
ILE A 124
ASN A  58
TYR A  85
 None
 0.98A 6a93B-1yckA:
undetectable		 6a93B-1yckA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 1yck PEPTIDOGLYCAN
RECOGNITION PROTEIN
(Homo
sapiens) 		4 / 5 ARG A  57
ALA A  56
TYR A  85
GLN A  54
 None
 1.15A 6f6sA-1yckA:
undetectable
6f6sB-1yckA:
0.0		 6f6sA-1yckA:
16.77
6f6sB-1yckA:
21.39