SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yd7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 1yd7 2-KETO
ACID:FERREDOXIN
OXIDOREDUCTASE
SUBUNIT ALPHA
(Pyrococcus
furiosus) 		4 / 7 GLN A  61
PHE A 163
MET A  48
ALA A  49
 None
 1.08A 1linA-1yd7A:
undetectable		 1linA-1yd7A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 1yd7 2-KETO
ACID:FERREDOXIN
OXIDOREDUCTASE
SUBUNIT ALPHA
(Pyrococcus
furiosus) 		4 / 7 GLY A  74
ILE A  69
THR A  84
MET A  62
 None
 0.93A 2xrhA-1yd7A:
undetectable		 2xrhA-1yd7A:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOB_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1yd7 2-KETO
ACID:FERREDOXIN
OXIDOREDUCTASE
SUBUNIT ALPHA
(Pyrococcus
furiosus) 		5 / 12 GLN A  16
PHE A 156
ALA A 155
PHE A  14
GLY A 182
 UNX  A 390 (-4.4A)
None
None
None
None
 1.50A 3aobC-1yd7A:
undetectable		 3aobC-1yd7A:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 1yd7 2-KETO
ACID:FERREDOXIN
OXIDOREDUCTASE
SUBUNIT ALPHA
(Pyrococcus
furiosus) 		5 / 12 ILE A  15
ALA A  22
GLU A  11
PRO A 193
ASN A 192
 None
 1.35A 3eigA-1yd7A:
undetectable		 3eigA-1yd7A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_B_VORB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1yd7 2-KETO
ACID:FERREDOXIN
OXIDOREDUCTASE
SUBUNIT ALPHA
(Pyrococcus
furiosus) 		5 / 11 PHE A   7
ILE A 190
ALA A  25
THR A 159
ALA A 155
 None
 1.12A 3mdtB-1yd7A:
undetectable		 3mdtB-1yd7A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 1yd7 2-KETO
ACID:FERREDOXIN
OXIDOREDUCTASE
SUBUNIT ALPHA
(Pyrococcus
furiosus) 		5 / 11 GLU A 186
GLY A  17
ILE A  21
PHE A 156
ALA A  22
 None
 1.16A 3nmuB-1yd7A:
undetectable
3nmuJ-1yd7A:
undetectable		 3nmuB-1yd7A:
23.33
3nmuJ-1yd7A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 1yd7 2-KETO
ACID:FERREDOXIN
OXIDOREDUCTASE
SUBUNIT ALPHA
(Pyrococcus
furiosus) 		5 / 10 LEU A 147
ASP A 178
VAL A 111
GLY A  17
LEU A 175
 None
 1.00A 3ogqA-1yd7A:
undetectable		 3ogqA-1yd7A:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 1yd7 2-KETO
ACID:FERREDOXIN
OXIDOREDUCTASE
SUBUNIT ALPHA
(Pyrococcus
furiosus) 		5 / 12 LEU A 175
VAL A 109
ALA A  25
GLU A 154
ALA A 155
 None
 1.25A 4fiaA-1yd7A:
undetectable		 4fiaA-1yd7A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 1yd7 2-KETO
ACID:FERREDOXIN
OXIDOREDUCTASE
SUBUNIT ALPHA
(Pyrococcus
furiosus) 		5 / 12 LEU A 175
VAL A 109
ALA A  25
GLU A 154
ALA A 155
 None
 1.25A 4fiaA-1yd7A:
undetectable		 4fiaA-1yd7A:
21.95