SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yd9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		4 / 6 PHE A 142
GLU A 108
LEU A 110
VAL A  78
 None
 0.90A 1hk1A-1yd9A:
undetectable		 1hk1A-1yd9A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		4 / 7 PHE A 142
GLU A 108
LEU A 110
VAL A  78
 None
 0.90A 1hk2A-1yd9A:
undetectable		 1hk2A-1yd9A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		4 / 5 ASP A  27
GLY A  51
PRO A 133
VAL A 173
 None
 0.86A 2aoiA-1yd9A:
undetectable		 2aoiA-1yd9A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR2_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		5 / 11 TYR A 171
GLN A  22
THR A  12
ILE A  31
PHE A   7
 None
 1.43A 2dr2A-1yd9A:
undetectable		 2dr2A-1yd9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		5 / 11 LEU A  21
LEU A  15
ILE A 155
LEU A 119
ASP A 123
 None
 1.25A 2q6hA-1yd9A:
undetectable		 2q6hA-1yd9A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		5 / 11 LEU A  21
LEU A  15
ILE A 155
LEU A 119
ASP A 123
 None
 1.19A 2q72A-1yd9A:
undetectable		 2q72A-1yd9A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		6 / 12 LEU A  21
LEU A  15
ILE A 155
PHE A 159
LEU A 119
ASP A 123
 None
 1.40A 2qb4A-1yd9A:
undetectable		 2qb4A-1yd9A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		5 / 11 LEU A  21
LEU A  15
ILE A 155
LEU A 119
ASP A 123
 None
 1.19A 2qeiA-1yd9A:
undetectable		 2qeiA-1yd9A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		3 / 3 SER A 156
ASP A 191
ASN A 193
 None
 0.69A 3lsfB-1yd9A:
undetectable
3lsfE-1yd9A:
undetectable		 3lsfB-1yd9A:
20.52
3lsfE-1yd9A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		3 / 3 ASP A 191
ASN A 193
SER A 156
 None
 0.68A 3lsfB-1yd9A:
undetectable
3lsfE-1yd9A:
undetectable		 3lsfB-1yd9A:
20.52
3lsfE-1yd9A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		3 / 3 ASP A 191
ASN A 193
SER A 156
 None
 0.88A 3lslA-1yd9A:
undetectable
3lslD-1yd9A:
undetectable		 3lslA-1yd9A:
20.69
3lslD-1yd9A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		3 / 3 SER A 156
ASP A 191
ASN A 193
 None
 0.90A 3lslA-1yd9A:
undetectable
3lslD-1yd9A:
undetectable		 3lslA-1yd9A:
20.69
3lslD-1yd9A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		3 / 3 SER A 165
ASP A  34
ASP A  32
 None
 0.83A 3uj7A-1yd9A:
undetectable		 3uj7A-1yd9A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		5 / 12 LEU A 119
CYH A 118
ILE A 151
ILE A 167
PHE A 172
 None
 1.22A 3vw1D-1yd9A:
undetectable		 3vw1D-1yd9A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		4 / 6 CYH A  97
THR A  40
ASN A  98
GLY A  80
 None
 1.36A 3w9tE-1yd9A:
undetectable		 3w9tE-1yd9A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		3 / 3 SER A 165
ASP A  34
ASP A  32
 None
 0.86A 4mwzA-1yd9A:
undetectable		 4mwzA-1yd9A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P68_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		5 / 11 ILE A 151
PHE A 132
SER A 165
ILE A 167
ILE A 155
 None
 1.37A 4p68A-1yd9A:
undetectable		 4p68A-1yd9A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		5 / 12 THR A  40
GLY A  48
HIS A  96
ASN A  41
SER A  84
 None
 1.36A 4pooB-1yd9A:
2.1		 4pooB-1yd9A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		5 / 12 GLY A  51
GLY A  47
ILE A  28
LYS A  57
LEU A  54
 None
 0.97A 5bw4A-1yd9A:
undetectable		 5bw4A-1yd9A:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		4 / 7 HIS A  96
LEU A  76
VAL A  83
SER A  84
 None
 1.04A 5m8rA-1yd9A:
undetectable		 5m8rA-1yd9A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		4 / 6 PRO A  75
GLY A  74
ASN A  73
LYS A  72
 None
 1.10A 5xxiA-1yd9A:
undetectable		 5xxiA-1yd9A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		3 / 3 TYR A 183
LEU A  21
ASP A 191
 None
 0.86A 5zv2B-1yd9A:
undetectable		 5zv2B-1yd9A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1yd9 CORE HISTONE
MACRO-H2A.1
(Rattus
norvegicus) 		5 / 12 ILE A 135
ALA A 147
ILE A 155
LEU A 111
ILE A 130
 None
 1.22A 6a5zD-1yd9A:
undetectable		 6a5zD-1yd9A:
17.46