SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ydg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1ydg TRP REPRESSOR
BINDING PROTEIN WRBA
(Deinococcus
radiodurans) 		5 / 10 SER A  83
SER A 117
LEU A   7
VAL A  36
VAL A 188
 None
 1.44A 1q23E-1ydgA:
undetectable		 1q23E-1ydgA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1ydg TRP REPRESSOR
BINDING PROTEIN WRBA
(Deinococcus
radiodurans) 		5 / 11 SER A  83
SER A 117
LEU A   7
VAL A  36
VAL A 188
 None
 1.32A 1q23J-1ydgA:
undetectable		 1q23J-1ydgA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1ydg TRP REPRESSOR
BINDING PROTEIN WRBA
(Deinococcus
radiodurans) 		5 / 10 SER A  83
SER A 117
LEU A   7
VAL A  36
VAL A 188
 None
 1.42A 1q23K-1ydgA:
undetectable		 1q23K-1ydgA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 1ydg TRP REPRESSOR
BINDING PROTEIN WRBA
(Deinococcus
radiodurans) 		4 / 6 GLY A  18
SER A  83
LEU A 176
ILE A 184
 SO4  A1302 (-3.6A)
None
None
None
 0.93A 1yajF-1ydgA:
undetectable		 1yajF-1ydgA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1ydg TRP REPRESSOR
BINDING PROTEIN WRBA
(Deinococcus
radiodurans) 		4 / 8 GLN A 129
ASP A 180
SER A 183
TYR A 152
 None
 1.12A 2xz5C-1ydgA:
undetectable
2xz5D-1ydgA:
undetectable		 2xz5C-1ydgA:
21.79
2xz5D-1ydgA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 1ydg TRP REPRESSOR
BINDING PROTEIN WRBA
(Deinococcus
radiodurans) 		4 / 8 LEU A 177
GLU A 178
GLU A  24
ALA A  25
 None
 0.79A 4rjdA-1ydgA:
undetectable
4rjdB-1ydgA:
undetectable		 4rjdA-1ydgA:
20.42
4rjdB-1ydgA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 1ydg TRP REPRESSOR
BINDING PROTEIN WRBA
(Deinococcus
radiodurans) 		4 / 6 VAL A   5
ALA A  79
GLN A 191
VAL A 192
 None
 1.03A 5i8fA-1ydgA:
undetectable		 5i8fA-1ydgA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 1ydg TRP REPRESSOR
BINDING PROTEIN WRBA
(Deinococcus
radiodurans) 		5 / 12 GLY A  29
GLY A  33
VAL A 188
LEU A   7
ALA A  79
 None
 0.95A 5kpcA-1ydgA:
undetectable		 5kpcA-1ydgA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 1ydg TRP REPRESSOR
BINDING PROTEIN WRBA
(Deinococcus
radiodurans) 		5 / 9 ALA A 122
SER A 121
GLY A 128
ALA A  91
SER A  84
 None
SO4  A1302 (-3.4A)
None
None
None
 0.97A 6bklE-1ydgA:
undetectable
6bklF-1ydgA:
undetectable
6bklG-1ydgA:
undetectable
6bklH-1ydgA:
undetectable		 6bklE-1ydgA:
7.96
6bklF-1ydgA:
7.96
6bklG-1ydgA:
7.96
6bklH-1ydgA:
7.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 1ydg TRP REPRESSOR
BINDING PROTEIN WRBA
(Deinococcus
radiodurans) 		5 / 12 GLY A  29
GLY A  33
GLU A  35
VAL A  36
ILE A   9
 None
 1.05A 6ectA-1ydgA:
undetectable		 6ectA-1ydgA:
20.97