SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ydw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		3 / 3 LYS A 141
ILE A 251
THR A 278
 None
 0.83A 1rx3A-1ydwA:
undetectable		 1rx3A-1ydwA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		3 / 3 ALA A  44
GLY A  35
SER A  65
 None
 0.60A 2ivuA-1ydwA:
undetectable		 2ivuA-1ydwA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		3 / 3 LEU A  99
TYR A  76
GLY A  13
 None
 0.61A 2ocuA-1ydwA:
1.7		 2ocuA-1ydwA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		3 / 3 LEU A 204
PRO A 205
LEU A 359
 None
 0.48A 2qd5B-1ydwA:
2.7		 2qd5B-1ydwA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 12 PHE A 202
ILE A 335
THR A 129
VAL A 262
ILE A 251
 None
 1.22A 3em0B-1ydwA:
undetectable		 3em0B-1ydwA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 7 ILE A 222
PHE A 162
PHE A 160
GLY A 226
 None
 0.94A 3em0B-1ydwA:
1.6		 3em0B-1ydwA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 12 GLY A 183
GLN A 340
VAL A 343
LYS A 176
PHE A 243
 None
 1.28A 3qowA-1ydwA:
3.0		 3qowA-1ydwA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 7 PRO A  80
LYS A 176
ARG A 174
GLY A 183
 None
 1.30A 3ucbB-1ydwA:
undetectable		 3ucbB-1ydwA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 11 VAL A  36
ALA A  37
SER A  40
GLY A  61
THR A  57
 None
 1.23A 4mmaA-1ydwA:
undetectable		 4mmaA-1ydwA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 12 ASP A 127
VAL A 104
GLY A 128
PHE A 160
GLY A 186
 None
 1.40A 4pevB-1ydwA:
6.4		 4pevB-1ydwA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_2
(PROTEASE)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 12 GLY A  10
GLY A  95
ILE A  72
VAL A  77
ILE A  98
 None
 1.01A 4q5mA-1ydwA:
undetectable		 4q5mA-1ydwA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 7 LYS A 102
PHE A 162
ARG A 174
ASP A 187
TYR A 191
 None
 1.11A 5a06A-1ydwA:
37.6		 5a06A-1ydwA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 7 PHE A 243
ARG A 174
ASP A 187
TYR A 191
 None
 1.40A 5a06A-1ydwA:
37.6		 5a06A-1ydwA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 7 LYS A 102
PHE A 162
ARG A 174
ASP A 187
TYR A 191
 None
 1.13A 5a06B-1ydwA:
37.5		 5a06B-1ydwA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 7 PHE A 243
ARG A 174
ASP A 187
TYR A 191
 None
 1.38A 5a06B-1ydwA:
37.5		 5a06B-1ydwA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 7 LYS A 102
PHE A 162
ARG A 174
ASP A 187
TYR A 191
 None
 1.13A 5a06C-1ydwA:
37.4		 5a06C-1ydwA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 7 LYS A 102
PHE A 162
ARG A 174
ASP A 187
TYR A 191
 None
 1.13A 5a06D-1ydwA:
37.4		 5a06D-1ydwA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 7 PHE A 243
ARG A 174
ASP A 187
TYR A 191
 None
 1.40A 5a06D-1ydwA:
37.4		 5a06D-1ydwA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 7 LYS A 102
PHE A 162
ARG A 174
ASP A 187
TYR A 191
 None
 1.12A 5a06E-1ydwA:
37.5		 5a06E-1ydwA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 7 PHE A 243
ARG A 174
ASP A 187
TYR A 191
 None
 1.41A 5a06E-1ydwA:
37.5		 5a06E-1ydwA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 7 LYS A 102
PHE A 162
ARG A 174
ASP A 187
TYR A 191
 None
 1.13A 5a06F-1ydwA:
37.5		 5a06F-1ydwA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 4 VAL A 208
ALA A 237
ILE A 193
THR A 196
 None
 1.12A 5e4dB-1ydwA:
0.0		 5e4dB-1ydwA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 5 PRO A 268
THR A 137
GLN A 306
THR A 129
 None
 1.27A 5h5fA-1ydwA:
2.5		 5h5fA-1ydwA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 1ydw AX110P-LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 8 THR A 209
SER A 228
THR A 207
SER A 230
 None
 0.96A 5l4eA-1ydwA:
undetectable
5l4eB-1ydwA:
undetectable
5l4eC-1ydwA:
undetectable
5l4eD-1ydwA:
undetectable
5l4eE-1ydwA:
undetectable		 5l4eA-1ydwA:
21.91
5l4eB-1ydwA:
21.91
5l4eC-1ydwA:
21.91
5l4eD-1ydwA:
21.91
5l4eE-1ydwA:
21.91