SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yf9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IGX_A_EPAA700_2 (PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1)	1yf9	UBIQUITIN CARRIER PROTEIN 4 (Leishmania major)	5 / 8	VAL A 42 VAL A 61 SER A 73 ILE A 97 LEU A 107	None	1.08A	1igxA-1yf9A: undetectable	1igxA-1yf9A: 15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N6D_B_H4BB600_1 (NITRIC OXIDE SYNTHASE)	1yf9	UBIQUITIN CARRIER PROTEIN 4 (Leishmania major)	4 / 6	TRP A 57 PHE A 44 VAL A 85 PRO A 47	None	1.29A	3n6dA-1yf9A: 0.0 3n6dB-1yf9A: 0.0	3n6dA-1yf9A: 17.97 3n6dB-1yf9A: 17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N6D_B_H4BB600_1 (NITRIC OXIDE SYNTHASE)	1yf9	UBIQUITIN CARRIER PROTEIN 4 (Leishmania major)	4 / 6	TRP A 57 PHE A 44 VAL A 92 PRO A 47	None	1.37A	3n6dA-1yf9A: 0.0 3n6dB-1yf9A: 0.0	3n6dA-1yf9A: 17.97 3n6dB-1yf9A: 17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V81_A_NVPA901_1 (HIV-1 REVERSE TRANSCRIPTASE P66 SUBUNIT)	1yf9	UBIQUITIN CARRIER PROTEIN 4 (Leishmania major)	4 / 8	LEU A 63 LYS A 70 LEU A 107 TYR A 67	None	1.08A	3v81A-1yf9A: undetectable	3v81A-1yf9A: 15.90

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1IGX_A_EPAA700_2","PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1","1yf9","UBIQUITIN CARRIER PROTEIN 4","Leishmania major",5,"VAL A  42;VAL A  61;SER A  73;ILE A  97;LEU A 107","None","1.08A","1igxA-1yf9A:undetectable","1igxA-1yf9A:15.25"],["3N6D_B_H4BB600_1","NITRIC OXIDE SYNTHASE;NITRIC OXIDE SYNTHASE","1yf9","UBIQUITIN CARRIER PROTEIN 4","Leishmania major",4,"TRP A  57;PHE A  44;VAL A  85;PRO A  47","None","1.29A","3n6dA-1yf9A:0.0;3n6dB-1yf9A:0.0","3n6dA-1yf9A:17.97;3n6dB-1yf9A:17.97"],["3N6D_B_H4BB600_1","NITRIC OXIDE SYNTHASE;NITRIC OXIDE SYNTHASE","1yf9","UBIQUITIN CARRIER PROTEIN 4","Leishmania major",4,"TRP A  57;PHE A  44;VAL A  92;PRO A  47","None","1.37A","3n6dA-1yf9A:0.0;3n6dB-1yf9A:0.0","3n6dA-1yf9A:17.97;3n6dB-1yf9A:17.97"],["3V81_A_NVPA901_1","HIV-1 REVERSE TRANSCRIPTASE P66 SUBUNIT","1yf9","UBIQUITIN CARRIER PROTEIN 4","Leishmania major",4,"LEU A  63;LYS A  70;LEU A 107;TYR A  67","None","1.08A","3v81A-1yf9A:undetectable","3v81A-1yf9A:15.90"]]