SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yfz'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PJ7_A_FFOA2887_0 (N,N-DIMETHYLGLYCINE OXIDASE)	1yfz	HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSF ERASE (Caldanaerobacter subterraneus)	5 / 12	MET A  51 LEU A  54 TYR A  33 GLY A  26 LEU A  62	None	1.15A	1pj7A-1yfzA: 0.5	1pj7A-1yfzA: 13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWX_B_EPAB3_1 (PROTEIN (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR-DELTA)))	1yfz	HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSF ERASE (Caldanaerobacter subterraneus)	5 / 12	LEU A 131 ILE A 130 LYS A 133 LEU A 175 TYR A 180	None None IMP  A1210 (-3.0A) None None	1.45A	3gwxB-1yfzA: undetectable	3gwxB-1yfzA: 23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JAY_A_SAMA1102_1 (STRUCTURAL PROTEIN VP3)	1yfz	HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSF ERASE (Caldanaerobacter subterraneus)	3 / 3	ARG A 136 ASP A 132 ASP A 105	None None IMP  A1210 (-4.2A)	0.85A	3jayA-1yfzA: 3.0	3jayA-1yfzA: 12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K8M_B_ACRB820_1 (ALPHA-AMYLASE, SUSG)	1yfz	HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSF ERASE (Caldanaerobacter subterraneus)	4 / 7	TYR A 166 GLU A 164 LEU A 169 ASN A 168	None	1.38A	3k8mB-1yfzA: undetectable	3k8mB-1yfzA: 15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WIP_J_ACHJ301_0 (ACETYLCHOLINE-BINDIN G PROTEIN)	1yfz	HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSF ERASE (Caldanaerobacter subterraneus)	4 / 8	ARG A 114 LEU A 110 TYR A  33 TYR A 145	None ACT  A1200 (-4.2A) None None	0.94A	3wipF-1yfzA: undetectable 3wipJ-1yfzA: undetectable	3wipF-1yfzA: 18.67 3wipJ-1yfzA: 18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_A_20JA602_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	1yfz	HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSF ERASE (Caldanaerobacter subterraneus)	4 / 7	VAL A 100 ARG A  56 ILE A  58 ALA A  57	None	0.72A	4lv9A-1yfzA: undetectable	4lv9A-1yfzA: 18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB602_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	1yfz	HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSF ERASE (Caldanaerobacter subterraneus)	4 / 7	VAL A 100 ARG A  56 ILE A  58 ALA A  57	None	0.73A	4lv9B-1yfzA: undetectable	4lv9B-1yfzA: 18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DLV_A_5D5A930_0 (ECTONUCLEOTIDE PYROPHOSPHATASE/PHOS PHODIESTERASE FAMILY MEMBER 2)	1yfz	HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSF ERASE (Caldanaerobacter subterraneus)	5 / 12	PHE A 148 LEU A 131 ILE A  99 PHE A  50 TYR A 158	None	1.47A	5dlvA-1yfzA: undetectable	5dlvA-1yfzA: 11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E72_A_SAMA400_1 (N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE)	1yfz	HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSF ERASE (Caldanaerobacter subterraneus)	4 / 4	ASP A 161 GLY A  46 ASP A 102 ASP A 105	MG  A1192 ( 2.6A) IMP  A1210 (-3.2A) MG  A1191 (-2.8A) IMP  A1210 (-4.2A)	1.14A	5e72A-1yfzA: undetectable	5e72A-1yfzA: 21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K4P_A_SORA611_0 (PROBABLE PHOSPHATIDYLETHANOLA MINE TRANSFERASE MCR-1)	1yfz	HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSF ERASE (Caldanaerobacter subterraneus)	4 / 6	GLY A  80 THR A  76 SER A  75 GLY A  73	None	0.85A	5k4pA-1yfzA: undetectable	5k4pA-1yfzA: 18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE8_B_08JB602_1 (CYTOCHROME P450 3A4)	1yfz	HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSF ERASE (Caldanaerobacter subterraneus)	4 / 8	LEU A  67 ILE A  48 ALA A  47 LEU A  44	None	0.80A	5te8B-1yfzA: undetectable	5te8B-1yfzA: 19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_B_ACTB308_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	1yfz	HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSF ERASE (Caldanaerobacter subterraneus)	3 / 3	LEU A  60 ILE A  58 TYR A 145	None	0.70A	5uunB-1yfzA: undetectable	5uunB-1yfzA: 23.31