SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yg0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 10 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 0.93A 1muiA-1yg0A:
undetectable		 1muiA-1yg0A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 0.95A 1sdtB-1yg0A:
undetectable		 1sdtB-1yg0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 0.99A 2avsB-1yg0A:
undetectable		 2avsB-1yg0A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 0.98A 2f80A-1yg0A:
undetectable		 2f80A-1yg0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 0.97A 2f80B-1yg0A:
undetectable		 2f80B-1yg0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 0.99A 2f81A-1yg0A:
undetectable		 2f81A-1yg0A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 0.96A 2f81B-1yg0A:
undetectable		 2f81B-1yg0A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 0.99A 2f8gA-1yg0A:
undetectable		 2f8gA-1yg0A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 0.96A 2ienB-1yg0A:
undetectable		 2ienB-1yg0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_CCSB417_0
(ESTROGEN RECEPTOR)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		3 / 3 GLN A  51
LYS A   1
VAL A  43
 None
 0.82A 2jfaB-1yg0A:
undetectable		 2jfaB-1yg0A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 1.04A 2qhcB-1yg0A:
undetectable		 2qhcB-1yg0A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 0.98A 2z54A-1yg0A:
undetectable		 2z54A-1yg0A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_2
(HIV-1 PROTEASE)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 0.96A 3d1zB-1yg0A:
undetectable		 3d1zB-1yg0A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 11 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 0.99A 3ektD-1yg0A:
undetectable		 3ektD-1yg0A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 1.03A 3mwsA-1yg0A:
undetectable		 3mwsA-1yg0A:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 0.96A 3ndtD-1yg0A:
undetectable		 3ndtD-1yg0A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 0.94A 3ndwA-1yg0A:
undetectable		 3ndwA-1yg0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 0.96A 3oxxA-1yg0A:
undetectable		 3oxxA-1yg0A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_2
(PROTEASE)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 0.97A 3pwmB-1yg0A:
undetectable		 3pwmB-1yg0A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_1
(PROTEASE)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 0.97A 3tkwA-1yg0A:
undetectable		 3tkwA-1yg0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_1
(PROTEASE)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 0.98A 4njvA-1yg0A:
undetectable		 4njvA-1yg0A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_1
(PROTEASE)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 1.08A 5t2zA-1yg0A:
undetectable		 5t2zA-1yg0A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 1yg0 COP ASSOCIATED
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  62
ALA A  61
ASP A  60
VAL A  23
ILE A  19
 None
 0.97A 6dh6A-1yg0A:
undetectable		 6dh6A-1yg0A:
23.17