SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yga'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 8 ALA A 268
LEU A 181
HIS A 233
LEU A 232
 None
 0.86A 1ereE-1ygaA:
undetectable		 1ereE-1ygaA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 8 ALA A 268
LEU A 181
HIS A 233
LEU A 232
 None
 0.86A 1ereF-1ygaA:
undetectable		 1ereF-1ygaA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_A_DOLA300_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 11 ILE A 171
LEU A  84
PRO A 137
LEU A  77
ASN A  87
 None
 1.39A 1mrlA-1ygaA:
undetectable
1mrlB-1ygaA:
0.0		 1mrlA-1ygaA:
20.82
1mrlB-1ygaA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_B_DOLB301_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 171
LEU A  84
PRO A 137
LEU A  77
ASN A  87
 None
 1.45A 1mrlB-1ygaA:
0.0
1mrlC-1ygaA:
0.0		 1mrlB-1ygaA:
20.82
1mrlC-1ygaA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_SAMA201_0
(UPF0066 PROTEIN
AF_0241)		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 ALA A  23
GLY A  45
ASP A  34
LEU A  32
SER A 177
 None
 1.32A 2nv4A-1ygaA:
0.0		 2nv4A-1ygaA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 ALA A  23
GLY A  45
ASP A  34
LEU A  32
SER A 177
 None
 1.31A 2nv4B-1ygaA:
undetectable		 2nv4B-1ygaA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 6 THR A 282
THR A 336
ASP A 156
THR A 154
 None
 1.15A 2okcB-1ygaA:
undetectable		 2okcB-1ygaA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 5 GLY A  64
HIS A  82
ASP A 167
ASP A 126
 None
 1.06A 2oxtB-1ygaA:
undetectable		 2oxtB-1ygaA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 11 TYR A 338
PHE A 179
GLN A  44
VAL A  42
VAL A  12
 None
 1.13A 2vcdA-1ygaA:
undetectable		 2vcdA-1ygaA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 10 TYR A 338
PHE A 179
ALA A 305
TYR A 178
GLN A 308
 None
 1.49A 2xtkB-1ygaA:
undetectable		 2xtkB-1ygaA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 8 VAL A  43
GLY A  60
TYR A  52
TYR A 146
 None
 0.87A 3af0A-1ygaA:
undetectable		 3af0A-1ygaA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 THR A 193
VAL A  42
LEU A  32
SER A 177
THR A 336
 None
 0.96A 3frqA-1ygaA:
undetectable		 3frqA-1ygaA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 332
SER A 256
GLY A 309
ARG A 310
 None
 1.24A 3v4tA-1ygaA:
undetectable
3v4tD-1ygaA:
undetectable		 3v4tA-1ygaA:
23.20
3v4tD-1ygaA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZF_B_ACTB502_0
(ALDOSE 1-EPIMERASE)		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 4 HIS A  94
HIS A 176
ASP A 240
TYR A 289
 None
 0.38A 4bzfB-1ygaA:
32.4		 4bzfB-1ygaA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 8 GLU A 278
GLU A 152
GLN A 337
LEU A 155
 None
 0.94A 4mj8A-1ygaA:
undetectable		 4mj8A-1ygaA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 232
GLY A 303
ASN A 180
LEU A 181
ALA A 268
 None
 1.15A 5kbwA-1ygaA:
undetectable		 5kbwA-1ygaA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 232
GLY A 303
ASN A 180
ALA A 268
TYR A 289
 None
 1.27A 5kbwB-1ygaA:
undetectable		 5kbwB-1ygaA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 232
GLY A 303
ASN A 180
LEU A 181
ALA A 268
 None
 1.18A 5kc4E-1ygaA:
undetectable		 5kc4E-1ygaA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 163
ALA A 168
LEU A  77
ARG A  65
ILE A 171
 None
 1.19A 5ljcA-1ygaA:
undetectable		 5ljcA-1ygaA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 1yga HYPOTHETICAL 37.9
KDA PROTEIN IN
BIO3-HXT17
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 10 ASP A  79
LEU A  77
ASP A 139
THR A 169
THR A 129
 None
 1.47A 6b4yA-1ygaA:
undetectable		 6b4yA-1ygaA:
20.00