SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ygm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 1ygm HYPOTHETICAL PROTEIN
BSU31320
(Bacillus
subtilis) 		4 / 7 GLU A 105
ASP A  68
THR A  71
ALA A  72
 None
 1.32A 3mbgA-1ygmA:
undetectable
3mbgB-1ygmA:
undetectable		 3mbgA-1ygmA:
24.14
3mbgB-1ygmA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 1ygm HYPOTHETICAL PROTEIN
BSU31320
(Bacillus
subtilis) 		4 / 5 THR A  93
ILE A  94
LYS A  90
GLU A  33
 None
 1.24A 4ac9C-1ygmA:
undetectable		 4ac9C-1ygmA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1ygm HYPOTHETICAL PROTEIN
BSU31320
(Bacillus
subtilis) 		4 / 5 THR A  93
ILE A  94
LYS A  90
GLU A  33
 None
 1.28A 4acaC-1ygmA:
undetectable		 4acaC-1ygmA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KSZ_A_CYSA620_0
(LACTOPEROXIDASE)		 1ygm HYPOTHETICAL PROTEIN
BSU31320
(Bacillus
subtilis) 		3 / 3 ARG A  11
GLU A  59
PHE A  51
 None
 0.78A 4kszA-1ygmA:
undetectable		 4kszA-1ygmA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)		 1ygm HYPOTHETICAL PROTEIN
BSU31320
(Bacillus
subtilis) 		4 / 6 GLU A  35
THR A  39
LEU A  16
GLN A  36
 None
 1.43A 4qztA-1ygmA:
undetectable		 4qztA-1ygmA:
23.85