SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ygp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 571
ALA A 610
GLY A 612
TYR A 613
 None
 0.67A 1c8lA-1ygpA:
45.8		 1c8lA-1ygpA:
48.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 571
ALA A 610
GLY A 612
TYR A 613
 None
 0.71A 1gfzA-1ygpA:
45.7		 1gfzA-1ygpA:
48.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_2
(HIV-II PROTEASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 8 ALA A 695
GLY A 485
ILE A 486
ILE A 703
ILE A 699
 None
 1.28A 1hshD-1ygpA:
undetectable		 1hshD-1ygpA:
9.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 571
ALA A 610
GLY A 612
TYR A 613
 None
 0.81A 1l5qA-1ygpA:
46.4		 1l5qA-1ygpA:
48.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 571
ALA A 610
GLY A 612
TYR A 613
 None
 0.81A 1l5qB-1ygpA:
46.4		 1l5qB-1ygpA:
48.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 571
ALA A 610
GLY A 612
TYR A 613
 None
 0.86A 1l7xA-1ygpA:
46.3		 1l7xA-1ygpA:
48.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 571
ALA A 610
GLY A 612
TYR A 613
 None
 0.86A 1l7xB-1ygpA:
46.2		 1l7xB-1ygpA:
48.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		3 / 3 ILE A 619
LEU A 622
VAL A 626
 None
 0.27A 1mz9B-1ygpA:
undetectable		 1mz9B-1ygpA:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QLT_A_ACTA601_0
(VANILLYL-ALCOHOL
OXIDASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 744
PHE A 750
ILE A 629
TYR A 587
 None
 1.49A 1qltA-1ygpA:
0.0		 1qltA-1ygpA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QLT_B_ACTB601_0
(VANILLYL-ALCOHOL
OXIDASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 744
PHE A 750
ILE A 629
TYR A 587
 None
 1.50A 1qltB-1ygpA:
0.0		 1qltB-1ygpA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.90A 1t85A-1ygpA:
0.0		 1t85A-1ygpA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 8 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.77A 1t86A-1ygpA:
undetectable		 1t86A-1ygpA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.84A 1t87A-1ygpA:
undetectable		 1t87A-1ygpA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.79A 1t87B-1ygpA:
undetectable		 1t87B-1ygpA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA1_1
(CES1 PROTEIN)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 686
GLY A 685
LEU A 805
LEU A 798
LEU A 502
 None
 1.04A 1ya4A-1ygpA:
3.4		 1ya4A-1ygpA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.78A 1yrcA-1ygpA:
0.0		 1yrcA-1ygpA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.74A 1yrdA-1ygpA:
0.0		 1yrdA-1ygpA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 11 PHE A 777
VAL A 741
ILE A 745
LEU A 742
ILE A 623
 None
 1.13A 2dg9A-1ygpA:
undetectable		 2dg9A-1ygpA:
10.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ECP_A_ACRA992_1
(MALTODEXTRIN
PHOSPHORYLASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		10 / 10 ASN A 133
LEU A 136
TYR A 280
ASP A 283
ARG A 292
ASP A 339
HIS A 341
ARG A 569
HIS A 571
ALA A 610
 None
None
None
None
None
None
None
PO4  A1900 (-3.7A)
None
None
 0.68A 2ecpA-1ygpA:
45.4		 2ecpA-1ygpA:
42.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ECP_B_ACRB992_1
(MALTODEXTRIN
PHOSPHORYLASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		10 / 10 ASN A 133
LEU A 136
TYR A 280
ASP A 283
ARG A 292
ASP A 339
HIS A 341
ARG A 569
HIS A 571
ALA A 610
 None
None
None
None
None
None
None
PO4  A1900 (-3.7A)
None
None
 0.61A 2ecpB-1ygpA:
45.3		 2ecpB-1ygpA:
42.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 6 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.83A 2feuA-1ygpA:
0.0		 2feuA-1ygpA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.83A 2feuB-1ygpA:
0.0		 2feuB-1ygpA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 5 ASP A  96
LEU A  99
MET A 102
ARG A 113
 None
 1.39A 2gj5A-1ygpA:
undetectable		 2gj5A-1ygpA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 6 ASN A 101
ASN A  97
GLN A 494
THR A 487
 None
 1.27A 2hkkA-1ygpA:
undetectable		 2hkkA-1ygpA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 159
LEU A  90
MET A  91
 None
 0.80A 2itzA-1ygpA:
undetectable		 2itzA-1ygpA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_B_AZZB1211_1
(DEOXYNUCLEOSIDE
KINASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 12 TRP A 534
LEU A 502
PHE A 530
VAL A 802
ALA A 806
 None
 1.47A 2jj8B-1ygpA:
undetectable		 2jj8B-1ygpA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A  12
GLY A   9
PHE A   8
PRO A   6
 None
 1.23A 2m2oB-1ygpA:
undetectable		 2m2oB-1ygpA:
2.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 223
ALA A 302
PHE A 298
LEU A  87
TYR A 161
 None
 1.10A 2nyrA-1ygpA:
undetectable		 2nyrA-1ygpA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 346
THR A 343
LEU A 444
HIS A 399
LEU A 396
 None
 1.02A 2qo5A-1ygpA:
undetectable		 2qo5A-1ygpA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 8 HIS A 728
ASP A 775
SER A 774
ASP A 769
 None
 1.08A 2xadA-1ygpA:
undetectable		 2xadA-1ygpA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 8 HIS A 728
ASP A 775
SER A 774
ASP A 769
 None
 1.07A 2xadB-1ygpA:
undetectable		 2xadB-1ygpA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 8 HIS A 728
ASP A 775
SER A 774
ASP A 769
 None
 1.08A 2xadD-1ygpA:
undetectable		 2xadD-1ygpA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 6 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.76A 2zuiA-1ygpA:
0.0		 2zuiA-1ygpA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 8 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.73A 2zujA-1ygpA:
undetectable		 2zujA-1ygpA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.76A 2zwtA-1ygpA:
0.0		 2zwtA-1ygpA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.77A 2zwuA-1ygpA:
0.0		 2zwuA-1ygpA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 5 VAL A 221
THR A 276
THR A 201
ARG A 220
 None
 1.11A 3bjwA-1ygpA:
undetectable		 3bjwA-1ygpA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 5 VAL A 221
THR A 276
THR A 201
ARG A 220
 None
 1.12A 3bjwC-1ygpA:
undetectable		 3bjwC-1ygpA:
9.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 571
ALA A 610
GLY A 612
TYR A 613
 None
 0.73A 3dd1A-1ygpA:
45.6		 3dd1A-1ygpA:
48.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 571
ALA A 610
GLY A 612
TYR A 613
 None
 0.77A 3dd1B-1ygpA:
45.9		 3dd1B-1ygpA:
48.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 571
ALA A 610
GLY A 612
TYR A 613
 None
 0.77A 3ddsA-1ygpA:
45.7		 3ddsA-1ygpA:
48.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 571
ALA A 610
GLY A 612
TYR A 613
 None
 0.76A 3ddsB-1ygpA:
46.0		 3ddsB-1ygpA:
48.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 571
ALA A 610
GLY A 612
TYR A 613
 None
 0.79A 3ddwA-1ygpA:
45.6		 3ddwA-1ygpA:
48.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 571
ALA A 610
GLY A 612
TYR A 613
 None
 0.79A 3ddwB-1ygpA:
46.2		 3ddwB-1ygpA:
48.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 447
ILE A 406
ILE A 403
THR A 343
 None
 0.87A 3deuA-1ygpA:
undetectable		 3deuA-1ygpA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.83A 3fwfA-1ygpA:
0.0		 3fwfA-1ygpA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.83A 3fwfB-1ygpA:
0.0		 3fwfB-1ygpA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.80A 3fwiA-1ygpA:
undetectable		 3fwiA-1ygpA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.81A 3fwjA-1ygpA:
0.0		 3fwjA-1ygpA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GP0_A_NILA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 347
LEU A 214
LEU A 359
ILE A 346
 None
 0.94A 3gp0A-1ygpA:
undetectable		 3gp0A-1ygpA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 4 ASP A 283
GLY A 288
LYS A 289
GLU A 290
 None
 1.33A 3hznD-1ygpA:
undetectable		 3hznD-1ygpA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 5 PRO A 342
SER A  86
LEU A 304
SER A 303
 None
 1.27A 3iluH-1ygpA:
undetectable		 3iluH-1ygpA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		3 / 3 PRO A 188
PHE A 228
ALA A  94
 None
 0.64A 3itaD-1ygpA:
undetectable		 3itaD-1ygpA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.84A 3l63A-1ygpA:
0.0		 3l63A-1ygpA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 583
ILE A 584
VAL A 642
ILE A 629
 None
 0.65A 3p4wC-1ygpA:
undetectable		 3p4wC-1ygpA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 122
LEU A 113
VAL A  35
ALA A  54
SER A  58
 None
 0.99A 3pghC-1ygpA:
undetectable		 3pghC-1ygpA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_A_FLRA700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 122
LEU A 113
VAL A  35
ALA A  54
SER A  58
 None
 0.98A 3rr3A-1ygpA:
undetectable		 3rr3A-1ygpA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_B_FLRB700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 122
LEU A 113
VAL A  35
ALA A  54
SER A  58
 None
 0.97A 3rr3B-1ygpA:
undetectable		 3rr3B-1ygpA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_C_FLRC700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 122
LEU A 113
VAL A  35
ALA A  54
SER A  58
 None
 0.98A 3rr3C-1ygpA:
undetectable		 3rr3C-1ygpA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_D_FLRD700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 122
LEU A 113
VAL A  35
ALA A  54
SER A  58
 None
 0.97A 3rr3D-1ygpA:
undetectable		 3rr3D-1ygpA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.81A 3wrhA-1ygpA:
0.0		 3wrhA-1ygpA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.80A 3wrjA-1ygpA:
0.0		 3wrjA-1ygpA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.78A 3wrlA-1ygpA:
0.0		 3wrlA-1ygpA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.86A 3wrlE-1ygpA:
undetectable		 3wrlE-1ygpA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.80A 3wrmA-1ygpA:
0.0		 3wrmA-1ygpA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.80A 3wrmF-1ygpA:
0.0		 3wrmF-1ygpA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 492
PHE A 233
THR A 508
ASP A 508
 None
 0.81A 4drjB-1ygpA:
undetectable		 4drjB-1ygpA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  59
LEU A  63
ILE A 104
GLY A 232
 None
 0.81A 4hb6A-1ygpA:
undetectable		 4hb6A-1ygpA:
5.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  59
LEU A  99
ILE A 104
GLY A 113
 None
 0.90A 4hb6A-1ygpA:
undetectable		 4hb6A-1ygpA:
5.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.88A 4l4gA-1ygpA:
0.0		 4l4gA-1ygpA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 502
LEU A 531
PHE A 530
THR A 506
LEU A 507
 None
 1.36A 4ltwA-1ygpA:
undetectable		 4ltwA-1ygpA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		6 / 12 VAL A 122
ILE A 113
LEU A 113
VAL A  35
ALA A  54
SER A  58
 None
 1.02A 4m11C-1ygpA:
undetectable		 4m11C-1ygpA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 122
ILE A 113
LEU A 113
ALA A  54
SER A  58
 None
 1.09A 4m11D-1ygpA:
undetectable		 4m11D-1ygpA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 122
ILE A 113
LEU A 113
VAL A  35
ALA A  54
 None
 0.96A 4m11D-1ygpA:
undetectable		 4m11D-1ygpA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 780
GLU A 664
LEU A 578
GLN A 566
 None
 1.48A 4qztB-1ygpA:
undetectable		 4qztB-1ygpA:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 PRO A 229
PHE A 228
TRP A 155
TYR A 157
 None
 1.47A 4v2yA-1ygpA:
0.0		 4v2yA-1ygpA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_A_LVYA151_1
(CEREBLON ISOFORM 4)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 PRO A 229
PHE A 228
TRP A 155
TYR A 157
 None
 1.46A 4v30A-1ygpA:
0.0		 4v30A-1ygpA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 8 PRO A 229
PHE A 228
TRP A 155
TYR A 157
 None
 1.46A 4v30B-1ygpA:
0.0		 4v30B-1ygpA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 482
ILE A 817
HIS A 450
TRP A 825
 None
 1.13A 4xo7B-1ygpA:
undetectable		 4xo7B-1ygpA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_A_EF2A151_1
(CEREBLON ISOFORM 4)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 PRO A 229
PHE A 228
TRP A 155
TYR A 157
 None
 1.48A 5amiA-1ygpA:
0.0		 5amiA-1ygpA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 PRO A 229
PHE A 228
TRP A 155
TYR A 157
 None
 1.50A 5amjB-1ygpA:
0.0		 5amjB-1ygpA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_B_EF2B151_1
(CEREBLON ISOFORM 4)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 PRO A 229
PHE A 228
TRP A 155
TYR A 157
 None
 1.45A 5amkB-1ygpA:
0.0		 5amkB-1ygpA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 140
GLY A 132
GLY A 137
GLY A 135
LEU A 131
 None
None
None
PLP  A 860 ( 3.3A)
None
 0.87A 5c0oH-1ygpA:
undetectable		 5c0oH-1ygpA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 728
ASP A 769
LEU A 761
PHE A 581
ILE A 765
 None
 1.43A 5dv4A-1ygpA:
undetectable		 5dv4A-1ygpA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 773
ILE A 666
ASN A 624
PHE A 581
 None
 0.99A 5hieC-1ygpA:
undetectable		 5hieC-1ygpA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_2
(TUBULIN BETA-2B
CHAIN)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 293
LEU A 344
ARG A 220
 None
 0.51A 5hnzB-1ygpA:
0.4		 5hnzB-1ygpA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 8 TYR A  84
PHE A 143
ILE A 824
TRP A 825
 None
 0.91A 5hw8H-1ygpA:
undetectable		 5hw8H-1ygpA:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 TYR A 587
ILE A 584
ILE A 583
ILE A 623
 None
 0.88A 5murB-1ygpA:
undetectable		 5murB-1ygpA:
6.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_0
(METHYLTRANSFERASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 444
ALA A 445
ILE A 367
GLU A 348
ALA A 364
 None
 1.06A 5n5dB-1ygpA:
undetectable		 5n5dB-1ygpA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 741
LYS A 591
MET A 592
 None
 1.06A 5nknA-1ygpA:
undetectable		 5nknA-1ygpA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 PRO A 229
PHE A 228
TRP A 155
TYR A 157
 None
 1.46A 5oh1A-1ygpA:
0.0		 5oh1A-1ygpA:
6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 PRO A 229
PHE A 228
TRP A 155
TYR A 157
 None
 1.48A 5oh1B-1ygpA:
0.0		 5oh1B-1ygpA:
6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 PRO A 229
PHE A 228
TRP A 155
TYR A 157
 None
 1.47A 5oh3A-1ygpA:
0.0		 5oh3A-1ygpA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 PRO A 229
PHE A 228
TRP A 155
TYR A 157
 None
 1.49A 5oh3B-1ygpA:
0.0		 5oh3B-1ygpA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 135
HIS A 377
VAL A 455
ASN A 484
GLY A 675
 PLP  A 860 ( 3.3A)
None
None
None
PLP  A 860 ( 4.1A)
 0.68A 5vncC-1ygpA:
15.1		 5vncC-1ygpA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 135
HIS A 377
VAL A 455
ASN A 484
LYS A 574
 PLP  A 860 ( 3.3A)
None
None
None
PO4  A1900 ( 3.7A)
 0.72A 5vncC-1ygpA:
15.1		 5vncC-1ygpA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 135
HIS A 377
VAL A 455
LYS A 574
GLU A 672
 PLP  A 860 ( 3.3A)
None
None
PO4  A1900 ( 3.7A)
None
 0.89A 5vncC-1ygpA:
15.1		 5vncC-1ygpA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		4 / 7 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.86A 5wk9A-1ygpA:
0.0		 5wk9A-1ygpA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_2
(CYTOCHROME P450 2C9)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 735
VAL A 762
ASP A 763
 None
 0.52A 5x23A-1ygpA:
undetectable		 5x23A-1ygpA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		3 / 3 PRO A 736
SER A 736
SER A 737
 None
 0.69A 6bpyA-1ygpA:
undetectable		 6bpyA-1ygpA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		7 / 12 GLY A 134
GLY A 135
ASP A 339
VAL A 455
ASN A 484
ARG A 569
GLY A 675
 PO4  A1900 (-3.7A)
PLP  A 860 ( 3.3A)
None
None
None
PO4  A1900 (-3.7A)
PLP  A 860 ( 4.1A)
 0.92A 6gneA-1ygpA:
21.7		 6gneA-1ygpA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		8 / 12 GLU A  88
GLY A 134
GLY A 135
ASP A 339
VAL A 455
ASN A 484
ARG A 569
GLY A 675
 None
PO4  A1900 (-3.7A)
PLP  A 860 ( 3.3A)
None
None
None
PO4  A1900 (-3.7A)
PLP  A 860 ( 4.1A)
 0.88A 6gneB-1ygpA:
21.8		 6gneB-1ygpA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_1
(-)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 12 ASP A 283
ASP A 339
HIS A 341
ARG A 569
GLU A 672
 None
None
None
PO4  A1900 (-3.7A)
None
 0.86A 6gnfA-1ygpA:
20.6		 6gnfA-1ygpA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_1
(-)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		6 / 12 ASP A 283
ASP A 339
HIS A 341
ASN A 484
ARG A 569
GLY A 675
 None
None
None
None
PO4  A1900 (-3.7A)
PLP  A 860 ( 4.1A)
 0.83A 6gnfA-1ygpA:
20.6		 6gnfA-1ygpA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_2
(-)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 9 GLY A 134
GLY A 135
TYR A 280
HIS A 377
VAL A 455
 PO4  A1900 (-3.7A)
PLP  A 860 ( 3.3A)
None
None
None
 0.80A 6gnfA-1ygpA:
20.5		 6gnfA-1ygpA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_1
(-)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 135
LEU A 136
TYR A 280
HIS A 377
VAL A 455
 PLP  A 860 ( 3.3A)
None
None
None
None
 0.76A 6gnfC-1ygpA:
20.8		 6gnfC-1ygpA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		5 / 12 ASP A 283
ASP A 339
HIS A 341
ARG A 569
GLU A 672
 None
None
None
PO4  A1900 (-3.7A)
None
 0.83A 6gnfC-1ygpA:
20.8		 6gnfC-1ygpA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		6 / 12 ASP A 283
ASP A 339
HIS A 341
ASN A 484
ARG A 569
GLY A 675
 None
None
None
None
PO4  A1900 (-3.7A)
PLP  A 860 ( 4.1A)
 0.80A 6gnfC-1ygpA:
20.8		 6gnfC-1ygpA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		6 / 12 GLY A 134
LEU A 136
ASP A 283
ASP A 339
HIS A 341
ASN A 484
 PO4  A1900 (-3.7A)
None
None
None
None
None
 0.99A 6gngA-1ygpA:
20.7		 6gngA-1ygpA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		7 / 12 GLU A  88
GLY A 135
TYR A 280
HIS A 377
VAL A 455
ARG A 569
GLU A 672
 None
PLP  A 860 ( 3.3A)
None
None
None
PO4  A1900 (-3.7A)
None
 0.87A 6gngA-1ygpA:
20.7		 6gngA-1ygpA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		7 / 12 GLU A  88
GLY A 135
TYR A 280
HIS A 377
VAL A 455
ARG A 569
GLY A 675
 None
PLP  A 860 ( 3.3A)
None
None
None
PO4  A1900 (-3.7A)
PLP  A 860 ( 4.1A)
 0.86A 6gngA-1ygpA:
20.7		 6gngA-1ygpA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		6 / 12 GLU A  88
GLY A 134
GLY A 135
LEU A 136
HIS A 341
ARG A 569
 None
PO4  A1900 (-3.7A)
PLP  A 860 ( 3.3A)
None
None
PO4  A1900 (-3.7A)
 0.50A 6gngB-1ygpA:
20.8		 6gngB-1ygpA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 1ygp YEAST GLYCOGEN
PHOSPHORYLASE
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 283
ASP A 339
ASN A 484
 None
 0.85A 6gngB-1ygpA:
20.8		 6gngB-1ygpA:
21.16