SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yhn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		5 / 12 THR A  40
GLY A  20
GLY A  18
GLY A  66
ASP A 128
 MG  A 302 ( 2.8A)
GTP  A 301 (-2.9A)
GTP  A 301 (-2.6A)
GTP  A 301 (-3.3A)
GTP  A 301 (-2.8A)
 1.06A 2b25A-1yhnA:
undetectable		 2b25A-1yhnA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		5 / 12 LEU A  46
VAL A  11
ILE A 169
VAL A 162
ILE A  61
 None
 0.87A 2f8gB-1yhnA:
undetectable		 2f8gB-1yhnA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		3 / 3 ARG A 103
ASP A 114
ASN A 147
 None
 0.86A 2zzmA-1yhnA:
undetectable		 2zzmA-1yhnA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		3 / 3 GLY A  18
GLY A  20
THR A  22
 GTP  A 301 (-2.6A)
GTP  A 301 (-2.9A)
MG  A 302 ( 3.3A)
 0.41A 3si7B-1yhnA:
undetectable		 3si7B-1yhnA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		4 / 6 ASP A  16
GLY A  18
VAL A  19
ASP A  89
 None
GTP  A 301 (-2.6A)
GTP  A 301 (-4.2A)
None
 1.06A 3vqrA-1yhnA:
undetectable		 3vqrA-1yhnA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		4 / 5 ASP A  16
GLY A  18
VAL A  19
ASP A  89
 None
GTP  A 301 (-2.6A)
GTP  A 301 (-4.2A)
None
 1.07A 3vqrB-1yhnA:
2.2		 3vqrB-1yhnA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		4 / 8 TYR A  78
VAL A  85
ILE A  13
ALA A  43
 None
 0.96A 4eyzA-1yhnA:
undetectable		 4eyzA-1yhnA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		4 / 8 TYR A  78
VAL A  85
ILE A  13
ALA A  43
 None
 0.96A 4eyzB-1yhnA:
undetectable		 4eyzB-1yhnA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		4 / 5 VAL A  52
LEU A 174
LEU A  56
ARG A  55
 None
 0.74A 4mghA-1yhnA:
3.2		 4mghA-1yhnA:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		4 / 8 ILE A 149
PHE A 120
GLN A 176
CYH A  83
 None
 0.98A 5dqyA-1yhnA:
undetectable		 5dqyA-1yhnA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IM2_A_BEZA401_0
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		5 / 12 PHE A 166
VAL A 121
ILE A  61
LEU A  24
VAL A  87
 None
 1.23A 5im2A-1yhnA:
undetectable		 5im2A-1yhnA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 1yhn RAB INTERACTING
LYSOSOMAL PROTEIN
(Homo
sapiens) 		3 / 3 VAL B 294
LYS B 302
MET B 305
 None
 0.90A 5nknA-1yhnB:
undetectable		 5nknA-1yhnB:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		3 / 3 VAL A  57
VAL A  50
GLN A 167
 None
 0.63A 5qgjA-1yhnA:
undetectable		 5qgjA-1yhnA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		3 / 3 VAL A  57
VAL A  50
GLN A 167
 None
 0.71A 5qglA-1yhnA:
undetectable		 5qglA-1yhnA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		3 / 3 VAL A  57
VAL A  50
GLN A 167
 None
 0.59A 5qgmA-1yhnA:
undetectable		 5qgmA-1yhnA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		3 / 3 VAL A  57
VAL A  50
GLN A 167
 None
 0.65A 5qgnA-1yhnA:
undetectable		 5qgnA-1yhnA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		3 / 3 VAL A  57
VAL A  50
GLN A 167
 None
 0.68A 5qguA-1yhnA:
undetectable		 5qguA-1yhnA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		3 / 3 VAL A  57
VAL A  50
GLN A 167
 None
 0.70A 5qgvA-1yhnA:
undetectable		 5qgvA-1yhnA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		3 / 3 VAL A  57
VAL A  50
GLN A 167
 None
 0.72A 5qgwA-1yhnA:
undetectable		 5qgwA-1yhnA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		3 / 3 VAL A  57
VAL A  50
GLN A 167
 None
 0.71A 5qgxA-1yhnA:
undetectable		 5qgxA-1yhnA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		3 / 3 VAL A  57
VAL A  50
GLN A 167
 None
 0.71A 5qh1A-1yhnA:
undetectable		 5qh1A-1yhnA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		3 / 3 VAL A  57
VAL A  50
GLN A 167
 None
 0.70A 5qh4A-1yhnA:
undetectable		 5qh4A-1yhnA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		3 / 3 VAL A  57
VAL A  50
GLN A 167
 None
 0.68A 5qh9A-1yhnA:
undetectable		 5qh9A-1yhnA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		3 / 3 VAL A  57
VAL A  50
GLN A 167
 None
 0.70A 5qhcA-1yhnA:
undetectable		 5qhcA-1yhnA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		3 / 3 VAL A  57
VAL A  50
GLN A 167
 None
 0.66A 5qheA-1yhnA:
undetectable		 5qheA-1yhnA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		3 / 3 VAL A  57
VAL A  50
GLN A 167
 None
 0.68A 5qhfA-1yhnA:
undetectable		 5qhfA-1yhnA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		3 / 3 VAL A  57
VAL A  50
GLN A 167
 None
 0.66A 5qhgA-1yhnA:
undetectable		 5qhgA-1yhnA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 1yhn RAS-RELATED PROTEIN
RAB-7
(Homo
sapiens) 		5 / 9 LEU A 123
VAL A  87
VAL A  85
ILE A  61
ASP A  63
 None
None
None
None
MG  A 302 (-2.7A)
 1.12A 5yf9X-1yhnA:
undetectable		 5yf9X-1yhnA:
18.09