SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yhp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1yhp CALCIUM-DEPENDENT
CELL ADHESION
MOLECULE-1
(Dictyostelium
discoideum) 		4 / 6 THR A 203
THR A  28
ASN A  38
ASP A  39
 None
 1.07A 2okcA-1yhpA:
undetectable		 2okcA-1yhpA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 1yhp CALCIUM-DEPENDENT
CELL ADHESION
MOLECULE-1
(Dictyostelium
discoideum) 		4 / 5 HIS A 153
SER A 170
THR A 190
ASP A 164
 None
 1.29A 3tm4A-1yhpA:
undetectable		 3tm4A-1yhpA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 1yhp CALCIUM-DEPENDENT
CELL ADHESION
MOLECULE-1
(Dictyostelium
discoideum) 		4 / 5 HIS A 153
SER A 170
THR A 190
ASP A 164
 None
 1.27A 3tm4B-1yhpA:
undetectable		 3tm4B-1yhpA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 1yhp CALCIUM-DEPENDENT
CELL ADHESION
MOLECULE-1
(Dictyostelium
discoideum) 		4 / 9 TYR A  23
PHE A  12
PHE A  31
ILE A  54
 None
 1.32A 4jvlA-1yhpA:
undetectable		 4jvlA-1yhpA:
20.27