SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yif'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DIT_P_2PPP1_1
(ALPHA-THROMBIN
PEPTIDE INHIBITOR
CVS995)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		4 / 6 LEU A  45
ILE A 318
GLU A  22
ASP A  23
 None
 1.13A 1ditH-1yifA:
undetectable
1ditP-1yifA:
undetectable		 1ditH-1yifA:
20.49
1ditP-1yifA:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_2
(HMG-COA REDUCTASE)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		4 / 8 SER A  29
VAL A  72
ASN A 103
ASP A 127
 None
 1.26A 1hwiB-1yifA:
undetectable		 1hwiB-1yifA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		4 / 8 SER A  29
VAL A  72
ASN A 103
ASP A 127
 None
 1.26A 1hwkA-1yifA:
undetectable		 1hwkA-1yifA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		4 / 8 SER A  29
VAL A  72
ASN A 103
ASP A 127
 None
 1.24A 1hwkC-1yifA:
undetectable		 1hwkC-1yifA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		4 / 8 SER A  29
VAL A  72
ASN A 103
ASP A 127
 None
 1.24A 1hwkD-1yifA:
undetectable		 1hwkD-1yifA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_1
(DNA GYRASE SUBUNIT B)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		5 / 12 ASP A  23
GLU A  22
ILE A 318
PRO A 319
THR A 256
 None
 1.29A 1kijA-1yifA:
undetectable		 1kijA-1yifA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		3 / 3 PHE A 379
TRP A  33
GLU A  32
 None
 1.17A 1mogA-1yifA:
undetectable		 1mogA-1yifA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		5 / 12 GLN A 244
THR A 265
GLY A 309
SER A 235
LEU A 311
 None
 1.09A 1rjdA-1yifA:
undetectable		 1rjdA-1yifA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		5 / 12 GLN A 244
THR A 265
GLY A 309
SER A 235
LEU A 311
 None
 1.10A 1rjdB-1yifA:
undetectable		 1rjdB-1yifA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNJ_A_225A501_1
(CYTOCHROME P450 2C8)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		5 / 10 ILE A  26
ALA A 262
VAL A   7
ILE A   3
VAL A 313
 None
 1.07A 2nnjA-1yifA:
undetectable		 2nnjA-1yifA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		3 / 3 SER A 494
THR A 505
PHE A 379
 None
 0.74A 2x91A-1yifA:
undetectable		 2x91A-1yifA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		5 / 12 LEU A  45
SER A  42
VAL A 252
ILE A 291
THR A 289
 None
 1.27A 3frqA-1yifA:
undetectable		 3frqA-1yifA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_2
(ADENOSYLHOMOCYSTEINA
SE)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		4 / 5 GLN A  56
THR A 326
HIS A  49
HIS A  53
 None
 1.19A 3g1uC-1yifA:
undetectable		 3g1uC-1yifA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA303_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		4 / 4 GLN A 421
GLN A 514
GLY A 367
HIS A 368
 None
 1.15A 3huoA-1yifA:
0.0		 3huoA-1yifA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_A_SALA301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		4 / 8 VAL A 252
VAL A   7
TYR A  24
ILE A  26
 None
 1.00A 3remA-1yifA:
undetectable		 3remA-1yifA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_B_SALB301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		4 / 8 VAL A 252
VAL A   7
TYR A  24
ILE A  26
 None
 1.01A 3remB-1yifA:
undetectable		 3remB-1yifA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		4 / 8 ARG A 207
HIS A 210
GLY A 502
ASN A 413
 None
 0.95A 3v3nB-1yifA:
undetectable		 3v3nB-1yifA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		4 / 8 ARG A 207
HIS A 210
GLY A 502
ASN A 413
 None
 0.95A 3v3nC-1yifA:
undetectable		 3v3nC-1yifA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		4 / 8 ASP A 114
GLY A 113
VAL A  37
SER A  16
 None
 0.89A 4acbB-1yifA:
undetectable
4acbC-1yifA:
undetectable		 4acbB-1yifA:
21.88
4acbC-1yifA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_C_ACTC506_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		4 / 5 ARG A 280
ILE A 276
HIS A 270
GLY A 281
 None
 1.45A 4e7cC-1yifA:
0.0		 4e7cC-1yifA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		4 / 5 ILE A 232
ARG A 216
ASP A 298
VAL A 304
 None
 1.23A 4nkxD-1yifA:
undetectable		 4nkxD-1yifA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		4 / 6 SER A  29
ARG A 207
GLY A 205
GLU A 209
 None
 0.87A 5cdqA-1yifA:
undetectable
5cdqC-1yifA:
undetectable
5cdqD-1yifA:
undetectable		 5cdqA-1yifA:
22.16
5cdqC-1yifA:
22.16
5cdqD-1yifA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHB_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		3 / 3 PHE A 402
ASP A 425
LEU A 420
 None
 0.80A 5uhbC-1yifA:
undetectable		 5uhbC-1yifA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		4 / 9 HIS A 227
ILE A 232
TYR A 196
ILE A  17
 None
 0.82A 5vkqB-1yifA:
undetectable
5vkqC-1yifA:
undetectable		 5vkqB-1yifA:
14.96
5vkqC-1yifA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		5 / 11 ALA A 507
HIS A  40
VAL A   7
THR A 265
ILE A  26
 None
 1.25A 5y80A-1yifA:
undetectable		 5y80A-1yifA:
9.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		5 / 9 TYR A  24
ASP A  44
ALA A 262
ILE A 291
SER A  42
 None
 1.32A 6awoA-1yifA:
undetectable		 6awoA-1yifA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		5 / 9 TYR A  24
ASP A  44
ALA A 262
ILE A 291
SER A  42
 None
 1.32A 6awqA-1yifA:
undetectable		 6awqA-1yifA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 1yif BETA-1,4-XYLOSIDASE
(Bacillus
subtilis) 		3 / 3 ILE A  26
ASN A   5
CYH A 246
 None
 0.84A 6bp4A-1yifA:
undetectable		 6bp4A-1yifA:
20.30