SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yj5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N8X_A_NIMA701_2 (PROSTAGLANDIN G/H SYNTHASE 1)	1yj5	5' POLYNUCLEOTIDE KINASE-3' PHOSPHATASE FHA DOMAIN (Mus musculus)	3 / 3	VAL C 74 SER C 72 LEU C 93	None	0.72A	3n8xA-1yj5C: undetectable	3n8xA-1yj5C: 13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DLZ_D_CYZD1302_0 (GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT)	1yj5	5' POLYNUCLEOTIDE KINASE-3' PHOSPHATASE FHA DOMAIN (Mus musculus)	5 / 11	ILE C 54 PRO C 57 SER C 59 LEU C 104 ASP C 91	None	1.38A	6dlzA-1yj5C: undetectable 6dlzD-1yj5C: undetectable	6dlzA-1yj5C: 17.36 6dlzD-1yj5C: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DM1_D_CYZD1302_0 (GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT)	1yj5	5' POLYNUCLEOTIDE KINASE-3' PHOSPHATASE FHA DOMAIN (Mus musculus)	5 / 11	ILE C 54 PRO C 57 SER C 59 LEU C 104 ASP C 91	None	1.37A	6dm1A-1yj5C: undetectable 6dm1D-1yj5C: undetectable	6dm1A-1yj5C: 17.36 6dm1D-1yj5C: 17.36

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3N8X_A_NIMA701_2","PROSTAGLANDIN G\/H SYNTHASE 1","1yj5","5' POLYNUCLEOTIDE KINASE-3' PHOSPHATASE FHA DOMAIN","Mus musculus",3,"VAL C  74;SER C  72;LEU C  93","None","0.72A","3n8xA-1yj5C:undetectable","3n8xA-1yj5C:13.50"],["6DLZ_D_CYZD1302_0","GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT","1yj5","5' POLYNUCLEOTIDE KINASE-3' PHOSPHATASE FHA DOMAIN","Mus musculus",5,"ILE C  54;PRO C  57;SER C  59;LEU C 104;ASP C  91","None","1.38A","6dlzA-1yj5C:undetectable;6dlzD-1yj5C:undetectable","6dlzA-1yj5C:17.36;6dlzD-1yj5C:17.36"],["6DM1_D_CYZD1302_0","GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT","1yj5","5' POLYNUCLEOTIDE KINASE-3' PHOSPHATASE FHA DOMAIN","Mus musculus",5,"ILE C  54;PRO C  57;SER C  59;LEU C 104;ASP C  91","None","1.37A","6dm1A-1yj5C:undetectable;6dm1D-1yj5C:undetectable","6dm1A-1yj5C:17.36;6dm1D-1yj5C:17.36"]]