SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yj7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 1yj7 ESCJ
(Escherichia
coli) 		5 / 11 VAL A  45
VAL A  61
ASN A  46
ARG A  68
ASP A  65
 None
 1.41A 1t6zB-1yj7A:
undetectable		 1t6zB-1yj7A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)		 1yj7 ESCJ
(Escherichia
coli) 		3 / 3 ASP A 126
ILE A 114
VAL A 159
 None
 0.59A 2avvD-1yj7A:
undetectable		 2avvD-1yj7A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 1yj7 ESCJ
(Escherichia
coli) 		3 / 3 VAL A  45
LYS A  21
MET A  20
 None
 1.10A 5nknA-1yj7A:
undetectable		 5nknA-1yj7A:
17.39