SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yjd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1yjd T-CELL-SPECIFIC
SURFACE GLYCOPROTEIN
CD28
FAB FRAGMENT OF
5.11A1 ANTIBODY
HEAVY CHAIN
(Homo
sapiens;
Mus
musculus) 		3 / 3 LYS C  95
ASP H 104
CYH H  50
 None
 1.33A 2br4F-1yjdC:
undetectable		 2br4F-1yjdC:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 1yjd T-CELL-SPECIFIC
SURFACE GLYCOPROTEIN
CD28
(Homo
sapiens) 		3 / 3 ARG C  34
ASN C  67
THR C  64
 None
 0.84A 2q63A-1yjdC:
undetectable		 2q63A-1yjdC:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 1yjd FAB FRAGMENT OF
5.11A1 ANTIBODY
HEAVY CHAIN
(Mus
musculus) 		4 / 5 ILE H  34
PRO H  53
TYR H  52
TYR H  33
 None
 0.91A 3d9lA-1yjdH:
undetectable
3d9lY-1yjdH:
undetectable		 3d9lA-1yjdH:
18.22
3d9lY-1yjdH:
5.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 1yjd FAB FRAGMENT OF
5.11A1 ANTIBODY
HEAVY CHAIN
(Mus
musculus) 		3 / 3 TYR H  94
GLN H  43
TRP H  47
 None
 1.03A 4kn2C-1yjdH:
undetectable		 4kn2C-1yjdH:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_B_DAHB60_1
(PUTATIVE CYTOCHROME
C)		 1yjd FAB FRAGMENT OF
5.11A1 ANTIBODY
HEAVY CHAIN
(Mus
musculus) 		4 / 5 MET H  81
ASN H  77
VAL H  72
LEU H  70
 None
 0.82A 5xdhB-1yjdH:
undetectable		 5xdhB-1yjdH:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 1yjd FAB FRAGMENT OF
5.11A1 ANTIBODY
HEAVY CHAIN
(Mus
musculus) 		4 / 6 MET H  81
ASN H  77
VAL H  72
LEU H  70
 None
 1.00A 5xdhA-1yjdH:
undetectable
5xdhC-1yjdH:
undetectable		 5xdhA-1yjdH:
19.16
5xdhC-1yjdH:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_D_DAHD60_1
(PUTATIVE CYTOCHROME
C)		 1yjd FAB FRAGMENT OF
5.11A1 ANTIBODY
HEAVY CHAIN
(Mus
musculus) 		4 / 5 MET H  81
ASN H  77
VAL H  72
LEU H  70
 None
 0.87A 5xdhD-1yjdH:
undetectable		 5xdhD-1yjdH:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1yjd FAB FRAGMENT OF
5.11A1 ANTIBODY
HEAVY CHAIN
(Mus
musculus) 		4 / 5 GLU H 155
PHE H 153
HIS H 206
THR H 117
 None
 1.09A 6b58A-1yjdH:
undetectable		 6b58A-1yjdH:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1yjd T-CELL-SPECIFIC
SURFACE GLYCOPROTEIN
CD28
(Homo
sapiens) 		3 / 3 GLN C  88
TYR C  85
ASN C  87
 None
NAG  C 203 (-3.4A)
NAG  C 203 (-1.9A)
 0.86A 6dwdC-1yjdC:
undetectable		 6dwdC-1yjdC:
12.91