SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ykw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		4 / 6 GLY A 219
TYR A 187
ALA A 183
GLU A 184
 None
 0.98A 1dmaB-1ykwA:
undetectable		 1dmaB-1ykwA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		4 / 8 THR A 124
PRO A 125
GLY A 126
THR A  36
 None
 0.71A 1h4oB-1ykwA:
undetectable		 1h4oB-1ykwA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		4 / 8 PHE A 137
TYR A 141
VAL A 116
VAL A 306
 None
 0.94A 1iwiA-1ykwA:
undetectable		 1iwiA-1ykwA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 PHE A 290
LEU A 270
MET A 307
ILE A 302
LEU A 113
 None
 1.19A 1lhuA-1ykwA:
undetectable		 1lhuA-1ykwA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		4 / 8 THR A 124
PRO A 125
GLY A 126
THR A  36
 None
 0.71A 1oc3A-1ykwA:
undetectable		 1oc3A-1ykwA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		4 / 8 ALA A 258
ASP A 241
ILE A 239
ILE A 263
 None
 0.90A 1p7lD-1ykwA:
undetectable		 1p7lD-1ykwA:
24.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		4 / 8 ALA A 258
ASP A 241
ILE A 239
ILE A 263
 None
 0.88A 1p7lC-1ykwA:
undetectable		 1p7lC-1ykwA:
24.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		4 / 8 ALA A 258
ASP A 241
ILE A 239
ILE A 263
 None
 0.93A 1rg9A-1ykwA:
undetectable		 1rg9A-1ykwA:
24.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		4 / 8 ALA A 258
ASP A 241
ILE A 239
ILE A 263
 None
 0.91A 1rg9D-1ykwA:
undetectable		 1rg9D-1ykwA:
24.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		4 / 8 ALA A 258
ASP A 241
ILE A 239
ILE A 263
 None
 0.90A 1rg9C-1ykwA:
undetectable		 1rg9C-1ykwA:
24.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 ILE A 239
ALA A 253
ALA A 215
VAL A 268
LEU A 284
 None
 1.13A 1xdkA-1ykwA:
undetectable		 1xdkA-1ykwA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		4 / 6 GLU A 201
ASP A 199
PHE A 182
ARG A 214
 None
 1.44A 2a3bB-1ykwA:
6.2		 2a3bB-1ykwA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		3 / 3 LYS A 344
ASP A  25
ASP A  69
 None
 1.08A 2br4A-1ykwA:
undetectable		 2br4A-1ykwA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		4 / 7 THR A 124
PRO A 125
GLY A 126
THR A  36
 None
 0.74A 2vl2B-1ykwA:
undetectable		 2vl2B-1ykwA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 8 PHE A 137
TYR A 141
VAL A 116
LEU A 313
VAL A 306
 None
 1.15A 2zujA-1ykwA:
undetectable		 2zujA-1ykwA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		3 / 3 CYH A 103
HIS A 102
PHE A 105
 None
 1.12A 3cr4X-1ykwA:
undetectable		 3cr4X-1ykwA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 GLY A 106
ILE A 135
LEU A  24
LEU A 142
LEU A 313
 None
 1.27A 3cs8A-1ykwA:
undetectable		 3cs8A-1ykwA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 8 GLY A 193
ALA A 396
GLY A 169
ILE A 196
ILE A 399
 None
 1.23A 3ekpA-1ykwA:
undetectable		 3ekpA-1ykwA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		3 / 3 VAL A 306
LYS A 309
HIS A 100
 None
 0.86A 3elzA-1ykwA:
undetectable		 3elzA-1ykwA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		4 / 7 LEU A 155
VAL A 355
LEU A 236
LEU A 270
 None
 0.83A 3g8iA-1ykwA:
undetectable		 3g8iA-1ykwA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 11 LEU A 177
SER A 178
PHE A 182
ILE A 185
GLU A 181
 None
 1.10A 3ko0A-1ykwA:
undetectable
3ko0B-1ykwA:
undetectable
3ko0C-1ykwA:
undetectable
3ko0D-1ykwA:
undetectable		 3ko0A-1ykwA:
12.47
3ko0B-1ykwA:
12.47
3ko0C-1ykwA:
12.47
3ko0D-1ykwA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 11 GLU A 181
LEU A 177
SER A 178
PHE A 182
ILE A 185
 None
 1.21A 3ko0C-1ykwA:
undetectable
3ko0D-1ykwA:
undetectable
3ko0E-1ykwA:
undetectable
3ko0F-1ykwA:
undetectable		 3ko0C-1ykwA:
12.47
3ko0D-1ykwA:
12.47
3ko0E-1ykwA:
12.47
3ko0F-1ykwA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 11 LEU A 177
SER A 178
PHE A 182
ILE A 185
GLU A 181
 None
 1.19A 3ko0C-1ykwA:
undetectable
3ko0D-1ykwA:
undetectable
3ko0E-1ykwA:
undetectable
3ko0F-1ykwA:
undetectable		 3ko0C-1ykwA:
12.47
3ko0D-1ykwA:
12.47
3ko0E-1ykwA:
12.47
3ko0F-1ykwA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 11 GLU A 181
LEU A 177
SER A 178
PHE A 182
ILE A 185
 None
 1.11A 3ko0E-1ykwA:
undetectable
3ko0F-1ykwA:
undetectable
3ko0G-1ykwA:
undetectable
3ko0H-1ykwA:
undetectable		 3ko0E-1ykwA:
12.47
3ko0F-1ykwA:
12.47
3ko0G-1ykwA:
12.47
3ko0H-1ykwA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 GLU A 181
LEU A 177
SER A 178
PHE A 182
ILE A 185
 None
 1.19A 3ko0G-1ykwA:
undetectable
3ko0H-1ykwA:
undetectable
3ko0I-1ykwA:
undetectable
3ko0J-1ykwA:
undetectable		 3ko0G-1ykwA:
12.47
3ko0H-1ykwA:
12.47
3ko0I-1ykwA:
12.47
3ko0J-1ykwA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 LEU A 177
SER A 178
PHE A 182
ILE A 185
GLU A 181
 None
 1.22A 3ko0K-1ykwA:
undetectable
3ko0L-1ykwA:
undetectable
3ko0S-1ykwA:
undetectable
3ko0T-1ykwA:
undetectable		 3ko0K-1ykwA:
12.47
3ko0L-1ykwA:
12.47
3ko0S-1ykwA:
12.47
3ko0T-1ykwA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 GLU A 181
LEU A 177
SER A 178
PHE A 182
ILE A 185
 None
 1.20A 3ko0K-1ykwA:
undetectable
3ko0L-1ykwA:
undetectable
3ko0M-1ykwA:
undetectable
3ko0N-1ykwA:
undetectable		 3ko0K-1ykwA:
12.47
3ko0L-1ykwA:
12.47
3ko0M-1ykwA:
12.47
3ko0N-1ykwA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 LEU A 177
SER A 178
PHE A 182
ILE A 185
GLU A 181
 None
 1.16A 3ko0M-1ykwA:
undetectable
3ko0N-1ykwA:
undetectable
3ko0O-1ykwA:
undetectable
3ko0P-1ykwA:
undetectable		 3ko0M-1ykwA:
12.47
3ko0N-1ykwA:
12.47
3ko0O-1ykwA:
12.47
3ko0P-1ykwA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 GLU A 181
LEU A 177
SER A 178
PHE A 182
ILE A 185
 None
 1.14A 3ko0M-1ykwA:
undetectable
3ko0N-1ykwA:
undetectable
3ko0O-1ykwA:
undetectable
3ko0P-1ykwA:
undetectable		 3ko0M-1ykwA:
12.47
3ko0N-1ykwA:
12.47
3ko0O-1ykwA:
12.47
3ko0P-1ykwA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SM2_A_478A126_2
(GAG-PRO-POL
POLYPROTEIN)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 11 ALA A 402
GLY A 395
ALA A 396
LEU A 363
LEU A 365
 None
 1.03A 3sm2B-1ykwA:
undetectable		 3sm2B-1ykwA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		4 / 7 GLY A 219
TYR A 187
ALA A 183
GLU A 184
 None
 0.93A 4hyfA-1ykwA:
undetectable		 4hyfA-1ykwA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 ILE A 285
ALA A 260
LEU A 262
ALA A 237
VAL A 380
 None
 1.14A 4k6iA-1ykwA:
undetectable		 4k6iA-1ykwA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 GLY A 315
PRO A 148
GLY A 147
PHE A 145
LEU A 276
 None
 1.29A 4n48A-1ykwA:
undetectable		 4n48A-1ykwA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		4 / 8 ALA A 258
ASP A 241
ILE A 239
ILE A 263
 None
 0.96A 4ndnD-1ykwA:
undetectable		 4ndnD-1ykwA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		3 / 3 VAL A 170
ALA A 197
PHE A 386
 None
 0.89A 4w5nA-1ykwA:
undetectable		 4w5nA-1ykwA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		3 / 3 GLU A 231
LYS A 233
ASN A 160
 None
 0.74A 4y1dA-1ykwA:
undetectable
4y1dD-1ykwA:
undetectable		 4y1dA-1ykwA:
18.29
4y1dD-1ykwA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		4 / 6 LEU A  22
LEU A 132
PHE A 137
LEU A 310
 None
 0.77A 5gs4A-1ykwA:
undetectable		 5gs4A-1ykwA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		4 / 5 LEU A  22
LEU A 132
PHE A 137
LEU A 310
 None
 0.80A 5gtrA-1ykwA:
undetectable		 5gtrA-1ykwA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		4 / 7 ILE A 185
HIS A 217
LEU A 218
ALA A 221
 None
 0.91A 5hrqE-1ykwA:
undetectable
5hrqF-1ykwA:
undetectable
5hrqJ-1ykwA:
undetectable		 5hrqE-1ykwA:
3.54
5hrqF-1ykwA:
5.31
5hrqJ-1ykwA:
5.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 11 ILE A 263
ILE A 239
THR A 280
ASP A 251
ALA A 258
 None
 1.14A 5lg3A-1ykwA:
undetectable		 5lg3A-1ykwA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		4 / 8 ALA A 258
ASP A 241
ILE A 239
ILE A 263
 None
 0.89A 5t8sA-1ykwA:
undetectable		 5t8sA-1ykwA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TQR_B_SAMB8009_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EZH2, POLYCOMB
PROTEIN SUZ12)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 10 LEU A 113
CYH A 117
GLY A 118
VAL A 130
TYR A 300
 None
 1.13A 5tqrB-1ykwA:
0.0		 5tqrB-1ykwA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V02_R_657R201_0
(CALMODULIN-1
SMALL CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL
PROTEIN 2)		 1ykw RUBISCO-LIKE PROTEIN
(Chlorobaculum
tepidum) 		5 / 10 LEU A  28
LEU A  38
GLU A  71
VAL A  72
ILE A  34
 None
 1.00A 5v02B-1ykwA:
undetectable
5v02R-1ykwA:
undetectable		 5v02B-1ykwA:
13.79
5v02R-1ykwA:
16.32