SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yli'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BF1_B_PAUB248_0 (TYPE III PANTOTHENATE KINASE)	1yli	PUTATIVE ACYL-COA THIOESTER HYDROLASE HI0827 (Haemophilus influenzae)	5 / 12	LEU A 19 VAL A 97 VAL A 16 GLY A 83 ILE A 49	None	1.16A	3bf1A-1yliA: undetectable 3bf1B-1yliA: undetectable	3bf1A-1yliA: 18.82 3bf1B-1yliA: 18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HGX_B_SALB104_1 (SALICYLATE BIOSYNTHESIS PROTEIN PCHB)	1yli	PUTATIVE ACYL-COA THIOESTER HYDROLASE HI0827 (Haemophilus influenzae)	5 / 9	ARG A 132 VAL A 59 VAL A 88 ILE A 134 ILE A 54	None	1.49A	3hgxB-1yliA: undetectable	3hgxB-1yliA: 18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GH8_B_MTXB201_1 (DIHYDROFOLATE REDUCTASE)	1yli	PUTATIVE ACYL-COA THIOESTER HYDROLASE HI0827 (Haemophilus influenzae)	5 / 12	ILE A 95 ALA A 48 ILE A 134 PRO A 135 ASN A 139	None	1.25A	4gh8B-1yliA: undetectable	4gh8B-1yliA: 21.64