SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yll'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 1yll CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 9 THR A 139
LEU A 193
ALA A  28
LEU A   7
GLU A  25
 None
 1.46A 2azqA-1yllA:
undetectable		 2azqA-1yllA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFF_A_QPSA600_1
(BETA-AMYLASE)		 1yll CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 190
GLU A 192
ARG A 121
GLY A 135
HIS A 134
 None
 1.19A 2xffA-1yllA:
undetectable		 2xffA-1yllA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 1yll CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ARG A  74
GLU A  49
SER A  80
 None
 0.86A 2xkkA-1yllA:
undetectable
2xkkC-1yllA:
undetectable		 2xkkA-1yllA:
13.59
2xkkC-1yllA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1yll CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 120
THR A 139
PHE A 109
ARG A  41
GLY A  39
 None
 1.43A 3aodC-1yllA:
undetectable		 3aodC-1yllA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1yll CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 PHE A  53
LEU A 101
GLY A  70
ILE A  63
 None
 0.88A 3wrkA-1yllA:
0.0		 3wrkA-1yllA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 1yll CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ASN A 110
ILE A 112
ASP A 108
LEU A 101
GLY A  22
 None
 1.16A 4o1eA-1yllA:
undetectable		 4o1eA-1yllA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 1yll CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ASN A 110
ILE A 112
ASP A 108
LEU A 101
GLY A  22
 None
 1.17A 4o1eB-1yllA:
undetectable		 4o1eB-1yllA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1yll CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ASP A  46
ARG A  61
ARG A  41
 None
 0.90A 4x5iA-1yllA:
undetectable		 4x5iA-1yllA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_1
(DIHYDROFOLATE
REDUCTASE)		 1yll CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ASP A  46
ARG A  61
ARG A  41
 None
 0.82A 5eajB-1yllA:
undetectable		 5eajB-1yllA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 1yll CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ARG A  72
HIS A  98
ARG A  74
 None
 0.98A 5iaoC-1yllA:
undetectable		 5iaoC-1yllA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 1yll CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ARG A  72
HIS A  98
ARG A  74
 None
 1.01A 5iaoF-1yllA:
undetectable		 5iaoF-1yllA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1yll CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 PHE A  53
LEU A 101
GLY A  70
ILE A  63
 None
 1.01A 5ik1A-1yllA:
0.0		 5ik1A-1yllA:
17.54