SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yn9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A1O_B_CAMB2422_0 (CYTOCHROME P450-CAM)	1yn9	POLYNUCLEOTIDE 5'-PHOSPHATASE (Autographa californica multiple nucleopolyhedrov irus)	5 / 9	TYR A 133 VAL A 117 GLY A 116 VAL A 15 ILE A 16	None	1.11A	2a1oB-1yn9A: undetectable	2a1oB-1yn9A: 18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WRK_A_CAMA502_0 (CAMPHOR 5-MONOOXYGENASE)	1yn9	POLYNUCLEOTIDE 5'-PHOSPHATASE (Autographa californica multiple nucleopolyhedrov irus)	4 / 5	PHE A 24 GLY A 56 ILE A 48 VAL A 49	None	0.83A	3wrkA-1yn9A: 0.0	3wrkA-1yn9A: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NQA_A_9CRA501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	1yn9	POLYNUCLEOTIDE 5'-PHOSPHATASE (Autographa californica multiple nucleopolyhedrov irus)	5 / 11	PHE A 149 ALA A 145 CYH A 119 HIS A 118 LEU A 61	None None PO4 A 601 (-3.1A) None None	1.15A	4nqaA-1yn9A: undetectable	4nqaA-1yn9A: 18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AP6_A_TLFA300_0 (PROBABLE STRIGOLACTONE ESTERASE DAD2)	1yn9	POLYNUCLEOTIDE 5'-PHOSPHATASE (Autographa californica multiple nucleopolyhedrov irus)	5 / 12	VAL A 117 PHE A 149 ILE A 146 VAL A 163 VAL A 130	None	1.17A	6ap6A-1yn9A: undetectable	6ap6A-1yn9A: 21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AP6_B_TLFB300_0 (PROBABLE STRIGOLACTONE ESTERASE DAD2)	1yn9	POLYNUCLEOTIDE 5'-PHOSPHATASE (Autographa californica multiple nucleopolyhedrov irus)	5 / 12	VAL A 117 PHE A 149 ILE A 146 VAL A 163 VAL A 130	None	1.16A	6ap6B-1yn9A: undetectable	6ap6B-1yn9A: 21.58

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2A1O_B_CAMB2422_0","CYTOCHROME P450-CAM","1yn9","POLYNUCLEOTIDE 5'-PHOSPHATASE","Autographa californica multiple nucleopolyhedrovirus",5,"TYR A 133;VAL A 117;GLY A 116;VAL A  15;ILE A  16","None","1.11A","2a1oB-1yn9A:undetectable","2a1oB-1yn9A:18.05"],["3WRK_A_CAMA502_0","CAMPHOR 5-MONOOXYGENASE","1yn9","POLYNUCLEOTIDE 5'-PHOSPHATASE","Autographa californica multiple nucleopolyhedrovirus",4,"PHE A  24;GLY A  56;ILE A  48;VAL A  49","None","0.83A","3wrkA-1yn9A:0.0","3wrkA-1yn9A:19.80"],["4NQA_A_9CRA501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","1yn9","POLYNUCLEOTIDE 5'-PHOSPHATASE","Autographa californica multiple nucleopolyhedrovirus",5,"PHE A 149;ALA A 145;CYH A 119;HIS A 118;LEU A  61","None;None;PO4 A 601 (-3.1A);None;None","1.15A","4nqaA-1yn9A:undetectable","4nqaA-1yn9A:18.11"],["6AP6_A_TLFA300_0","PROBABLE STRIGOLACTONE ESTERASE DAD2","1yn9","POLYNUCLEOTIDE 5'-PHOSPHATASE","Autographa californica multiple nucleopolyhedrovirus",5,"VAL A 117;PHE A 149;ILE A 146;VAL A 163;VAL A 130","None","1.17A","6ap6A-1yn9A:undetectable","6ap6A-1yn9A:21.58"],["6AP6_B_TLFB300_0","PROBABLE STRIGOLACTONE ESTERASE DAD2","1yn9","POLYNUCLEOTIDE 5'-PHOSPHATASE","Autographa californica multiple nucleopolyhedrovirus",5,"VAL A 117;PHE A 149;ILE A 146;VAL A 163;VAL A 130","None","1.16A","6ap6B-1yn9A:undetectable","6ap6B-1yn9A:21.58"]]