SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yna'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		4 / 4 GLY A  43
ASP A  41
GLY A 184
THR A  26
 None
 1.02A 1hxbB-1ynaA:
undetectable		 1hxbB-1ynaA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KVL_A_CLSA371_1
(BETA-LACTAMASE)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		5 / 10 GLY A  48
ASN A  29
TYR A  15
THR A 177
GLY A  47
 None
 0.95A 1kvlA-1ynaA:
undetectable		 1kvlA-1ynaA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCB_P_DHIP3_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-L-GLN-D-PHE
-L-HIS-D-PRO-OH)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		4 / 5 TYR A  73
TYR A 180
GLU A 178
TYR A  96
 None
 1.46A 1mcbA-1ynaA:
0.6
1mcbB-1ynaA:
0.8
1mcbP-1ynaA:
undetectable		 1mcbA-1ynaA:
23.21
1mcbB-1ynaA:
23.21
1mcbP-1ynaA:
4.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		4 / 7 LEU A 105
LEU A 117
SER A 139
VAL A  85
 None
 0.93A 1tyrB-1ynaA:
undetectable		 1tyrB-1ynaA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		4 / 8 TYR A 115
ARG A 141
GLU A  91
VAL A 108
 None
 1.13A 2fl5E-1ynaA:
undetectable
2fl5F-1ynaA:
undetectable		 2fl5E-1ynaA:
21.08
2fl5F-1ynaA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		4 / 7 TYR A 180
GLY A  22
ALA A  23
LEU A  45
 None
 0.79A 2wekB-1ynaA:
undetectable		 2wekB-1ynaA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		3 / 3 GLY A  22
GLY A  40
GLY A  42
 None
 0.40A 3bogC-1ynaA:
undetectable		 3bogC-1ynaA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		4 / 7 LEU A 105
LEU A 117
SER A 139
VAL A  85
 None
 0.74A 3d2tA-1ynaA:
undetectable		 3d2tA-1ynaA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		4 / 8 GLY A  21
GLY A  22
GLY A  42
SER A  19
 None
 0.61A 3d41A-1ynaA:
undetectable		 3d41A-1ynaA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		4 / 7 TYR A  88
TYR A  77
TYR A 172
TYR A  35
 None
 1.35A 3ku9B-1ynaA:
undetectable		 3ku9B-1ynaA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_1
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		4 / 6 GLY A  33
THR A  34
LEU A  30
ASP A  11
 None
 0.87A 3ps9A-1ynaA:
undetectable		 3ps9A-1ynaA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		4 / 6 VAL A  46
ASN A   5
TYR A  77
GLU A  86
 None
 1.23A 3q5sA-1ynaA:
undetectable		 3q5sA-1ynaA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		3 / 3 TYR A 115
PHE A  62
ARG A 141
 None
 1.09A 4g19D-1ynaA:
undetectable		 4g19D-1ynaA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		4 / 6 SER A  16
GLU A   7
GLY A  43
GLY A  21
 None
 0.87A 5cdpA-1ynaA:
undetectable
5cdpB-1ynaA:
undetectable		 5cdpA-1ynaA:
16.77
5cdpB-1ynaA:
18.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		4 / 8 THR A 120
ARG A 122
GLN A 136
TRP A 138
 None
 0.44A 5tzoA-1ynaA:
27.7		 5tzoA-1ynaA:
44.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		6 / 12 VAL A  46
TRP A  79
TYR A  88
PRO A 126
TRP A 138
TYR A 172
 None
 0.65A 5tzoA-1ynaA:
27.7		 5tzoA-1ynaA:
44.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		5 / 12 VAL A  46
TRP A  79
TYR A  88
TRP A 138
TYR A 172
 None
 0.58A 5tzoB-1ynaA:
27.7		 5tzoB-1ynaA:
44.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		4 / 8 THR A 120
ARG A 122
GLN A 136
TRP A 138
 None
 0.50A 5tzoB-1ynaA:
27.7		 5tzoB-1ynaA:
44.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		6 / 12 VAL A  46
TRP A  79
TYR A  88
PRO A 126
TRP A 138
TYR A 172
 None
 0.69A 5tzoC-1ynaA:
27.5		 5tzoC-1ynaA:
44.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		4 / 8 THR A 120
ARG A 122
GLN A 136
TRP A 138
 None
 0.42A 5tzoC-1ynaA:
27.5		 5tzoC-1ynaA:
44.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		4 / 7 GLY A  94
THR A  95
SER A 183
SER A 182
 None
 0.94A 6jnhA-1ynaA:
undetectable		 6jnhA-1ynaA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1yna ENDO-1,4-BETA-XYLANA
SE
(Thermomyces
lanuginosus) 		4 / 6 GLY A  94
THR A  95
SER A 183
SER A 182
 None
 0.98A 6jogA-1ynaA:
undetectable		 6jogA-1ynaA:
20.39