SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ynb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1ynb HYPOTHETICAL PROTEIN
AF1432
(Archaeoglobus
fulgidus) 		4 / 5 SER A  26
GLY A  27
HIS A  74
ASP A 122
 None
 1.14A 2oxtB-1ynbA:
undetectable		 2oxtB-1ynbA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1ynb HYPOTHETICAL PROTEIN
AF1432
(Archaeoglobus
fulgidus) 		5 / 8 LEU A 126
ILE A  49
LEU A  53
THR A 153
LEU A 151
 None
 1.50A 2xfhA-1ynbA:
2.8		 2xfhA-1ynbA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 1ynb HYPOTHETICAL PROTEIN
AF1432
(Archaeoglobus
fulgidus) 		4 / 8 SER A  26
GLU A  37
PHE A 145
LEU A 128
 None
 1.02A 3i45A-1ynbA:
undetectable		 3i45A-1ynbA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1ynb HYPOTHETICAL PROTEIN
AF1432
(Archaeoglobus
fulgidus) 		4 / 8 ALA A 155
ALA A 156
ILE A 159
ALA A  47
 None
 0.56A 4v1fA-1ynbA:
undetectable
4v1fB-1ynbA:
undetectable		 4v1fA-1ynbA:
21.34
4v1fB-1ynbA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 1ynb HYPOTHETICAL PROTEIN
AF1432
(Archaeoglobus
fulgidus) 		3 / 3 THR A 153
ASP A 154
ALA A 155
 None
 0.11A 5g5gB-1ynbA:
undetectable		 5g5gB-1ynbA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1ynb HYPOTHETICAL PROTEIN
AF1432
(Archaeoglobus
fulgidus) 		4 / 7 HIS A  74
HIS A  42
ASN A  43
VAL A 120
 None
 1.02A 5m8rA-1ynbA:
undetectable		 5m8rA-1ynbA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1ynb HYPOTHETICAL PROTEIN
AF1432
(Archaeoglobus
fulgidus) 		4 / 8 HIS A  74
HIS A  42
ASN A  43
VAL A 120
 None
 0.99A 5m8rD-1ynbA:
undetectable		 5m8rD-1ynbA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1ynb HYPOTHETICAL PROTEIN
AF1432
(Archaeoglobus
fulgidus) 		4 / 8 ALA A 146
VAL A 149
LEU A 151
ILE A  49
 None
 0.85A 5nujA-1ynbA:
undetectable		 5nujA-1ynbA:
20.59