SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yni'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		5 / 12 LEU A  46
TYR A 402
GLY A  10
GLY A 362
LEU A 353
 None
 1.05A 1fe2A-1yniA:
undetectable		 1fe2A-1yniA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		3 / 3 LEU A 165
PRO A 166
LEU A 171
 None
 0.55A 1hrkA-1yniA:
undetectable		 1hrkA-1yniA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		5 / 12 LEU A  46
TYR A 402
GLY A  10
GLY A 362
LEU A 353
 None
 1.05A 1igxA-1yniA:
undetectable		 1igxA-1yniA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		5 / 12 THR A 128
VAL A 129
GLY A 175
GLY A 197
ALA A 217
 None
 0.87A 1jg4A-1yniA:
undetectable		 1jg4A-1yniA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		5 / 12 THR A 128
VAL A 129
GLY A 197
ALA A 217
VAL A 221
 None
 1.04A 1jg4A-1yniA:
undetectable		 1jg4A-1yniA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		4 / 8 ARG A 212
ASN A 134
GLN A 167
ASN A 110
 SUG  A1001 (-3.0A)
None
None
SUG  A1001 (-3.2A)
 1.33A 1p6kA-1yniA:
undetectable		 1p6kA-1yniA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		4 / 8 ARG A 212
ASN A 134
GLN A 167
ASN A 110
 SUG  A1001 (-3.0A)
None
None
SUG  A1001 (-3.2A)
 1.32A 1p6kB-1yniA:
undetectable		 1p6kB-1yniA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		4 / 6 TYR A  18
HIS A  16
GLU A 324
PRO A 322
 None
 1.29A 1q13A-1yniA:
undetectable		 1q13A-1yniA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		4 / 8 ARG A 212
ASN A 134
GLN A 167
ASN A 110
 SUG  A1001 (-3.0A)
None
None
SUG  A1001 (-3.2A)
 1.28A 1rs7B-1yniA:
undetectable		 1rs7B-1yniA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		4 / 4 THR A 373
GLY A 123
ASP A 122
ALA A 115
 None
 1.15A 1sg9A-1yniA:
undetectable		 1sg9A-1yniA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_D_PAUD6004_0
(PANTOTHENATE KINASE)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		5 / 10 VAL A 195
LEU A 274
LEU A 193
ILE A 252
ASN A 249
 None
 1.46A 1sq5D-1yniA:
undetectable		 1sq5D-1yniA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		3 / 3 GLU A 200
GLU A 219
LEU A 165
 None
 0.74A 1v8bA-1yniA:
undetectable		 1v8bA-1yniA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		3 / 3 GLU A 200
GLU A 219
LEU A 165
 None
 0.75A 1v8bB-1yniA:
undetectable		 1v8bB-1yniA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		3 / 3 GLU A 324
THR A 302
LEU A 335
 None
 0.65A 1v8bC-1yniA:
undetectable		 1v8bC-1yniA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		4 / 8 ARG A 212
ASN A 134
GLN A 167
ASN A 110
 SUG  A1001 (-3.0A)
None
None
SUG  A1001 (-3.2A)
 1.30A 1zzqA-1yniA:
undetectable		 1zzqA-1yniA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		4 / 8 ARG A 212
ASN A 134
GLN A 167
ASN A 110
 SUG  A1001 (-3.0A)
None
None
SUG  A1001 (-3.2A)
 1.28A 1zzqB-1yniA:
undetectable		 1zzqB-1yniA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		4 / 8 ARG A 212
ASN A 134
GLN A 167
ASN A 110
 SUG  A1001 (-3.0A)
None
None
SUG  A1001 (-3.2A)
 1.32A 1zzuB-1yniA:
undetectable		 1zzuB-1yniA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_SAMA201_0
(UPF0066 PROTEIN
AF_0241)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		5 / 12 ALA A 364
GLN A  59
GLY A  45
LEU A  46
SER A 356
 None
 1.36A 2nv4A-1yniA:
0.0		 2nv4A-1yniA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		5 / 12 ALA A 364
GLN A  59
GLY A  45
LEU A  46
SER A 356
 None
 1.29A 2nv4B-1yniA:
undetectable		 2nv4B-1yniA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		4 / 8 ARG A 212
PRO A 322
GLY A 361
MET A 357
 SUG  A1001 (-3.0A)
None
SUG  A1001 ( 4.2A)
None
 1.04A 2qd5B-1yniA:
undetectable		 2qd5B-1yniA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		3 / 3 ASN A 256
ARG A 257
ASP A 314
 None
 0.85A 2qe6A-1yniA:
undetectable		 2qe6A-1yniA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		3 / 3 ASN A 256
ARG A 257
ASP A 314
 None
 0.89A 2qe6B-1yniA:
undetectable		 2qe6B-1yniA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		5 / 10 GLN A 270
LEU A 274
LEU A 273
LEU A 193
LEU A 277
 None
 1.16A 2riwA-1yniA:
undetectable
2riwB-1yniA:
undetectable		 2riwA-1yniA:
22.06
2riwB-1yniA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		4 / 7 VAL A 195
LEU A 193
ILE A 252
ASN A 249
 None
 0.81A 3avpA-1yniA:
undetectable		 3avpA-1yniA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		3 / 3 GLY A 175
ASP A 173
SER A 218
 None
 0.65A 3brfA-1yniA:
undetectable		 3brfA-1yniA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_B_DESB800_1
(ESTROGEN RECEPTOR
ALPHA)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		5 / 10 ALA A 286
GLU A 288
LEU A 277
LEU A 274
LEU A 182
 None
 1.40A 3erdB-1yniA:
undetectable		 3erdB-1yniA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		4 / 4 LEU A 417
PRO A 414
LEU A  86
ARG A  74
 None
 1.33A 3hcoA-1yniA:
undetectable		 3hcoA-1yniA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		5 / 12 TYR A 402
ASN A 306
GLY A  10
GLY A 362
LEU A 353
 None
SUG  A1001 ( 4.1A)
None
None
None
 1.02A 3hs6B-1yniA:
undetectable		 3hs6B-1yniA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		5 / 12 ILE A  62
GLY A  10
ALA A 103
VAL A 108
ASN A 110
 None
None
None
None
SUG  A1001 (-3.2A)
 1.07A 3jb3A-1yniA:
undetectable		 3jb3A-1yniA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		5 / 12 ILE A  62
GLY A  10
ALA A 109
VAL A 108
PRO A 105
 None
None
SUG  A1001 (-3.6A)
None
None
 0.87A 3jb3A-1yniA:
undetectable		 3jb3A-1yniA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		6 / 11 ARG A 367
VAL A 320
LEU A 321
LEU A 310
GLY A 362
ALA A 364
 None
 1.50A 3pghB-1yniA:
undetectable		 3pghB-1yniA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		5 / 12 TYR A 402
ASN A 306
GLY A  10
GLY A 362
LEU A 353
 None
SUG  A1001 ( 4.1A)
None
None
None
 0.91A 4e1gA-1yniA:
undetectable		 4e1gA-1yniA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		5 / 12 LEU A 406
LEU A  40
ALA A  41
GLN A  44
ALA A 358
 None
 1.13A 4fn9A-1yniA:
undetectable		 4fn9A-1yniA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		4 / 8 ASN A  25
ALA A  27
SER A  28
TYR A  18
 SUG  A1001 (-3.9A)
None
SUG  A1001 (-2.7A)
None
 0.99A 4ijiF-1yniA:
undetectable		 4ijiF-1yniA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		4 / 7 ASN A  25
ALA A  27
SER A  28
TYR A  18
 SUG  A1001 (-3.9A)
None
SUG  A1001 (-2.7A)
None
 0.98A 4ijiH-1yniA:
undetectable		 4ijiH-1yniA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KSZ_A_CYSA620_0
(LACTOPEROXIDASE)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		3 / 3 ARG A 377
GLU A 376
PHE A 159
 None
 0.90A 4kszA-1yniA:
0.0		 4kszA-1yniA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		3 / 3 PRO A 363
LEU A 366
HIS A  16
 None
 0.61A 4pevA-1yniA:
undetectable		 4pevA-1yniA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		5 / 12 ARG A 198
GLY A 197
ALA A 211
ALA A 169
VAL A 168
 None
 1.29A 4ryaA-1yniA:
undetectable		 4ryaA-1yniA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		3 / 3 ARG A 403
ASP A 404
ARG A  39
 None
 0.61A 4wq4B-1yniA:
undetectable		 4wq4B-1yniA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		5 / 11 ALA A 286
GLU A 288
LEU A 277
LEU A 274
LEU A 182
 None
 1.35A 4zn7B-1yniA:
undetectable		 4zn7B-1yniA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		4 / 8 GLY A 360
GLY A 361
VAL A 251
HIS A 248
 SUG  A1001 (-4.5A)
SUG  A1001 ( 4.2A)
None
SUG  A1001 (-4.0A)
 0.78A 5f8yB-1yniA:
undetectable		 5f8yB-1yniA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		4 / 7 SER A  28
ALA A  27
GLY A 361
ARG A 212
 SUG  A1001 (-2.7A)
None
SUG  A1001 ( 4.2A)
SUG  A1001 (-3.0A)
 0.90A 5fpdB-1yniA:
undetectable		 5fpdB-1yniA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWZ_D_010D6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
PEDV MAIN PROTEASE)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		3 / 3 MET A 106
HIS A  16
GLY A 361
 None
None
SUG  A1001 ( 4.2A)
 0.77A 5gwzB-1yniA:
undetectable		 5gwzB-1yniA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		5 / 12 GLY A 175
ASN A 178
ALA A 364
VAL A 108
ASN A 306
 None
None
None
None
SUG  A1001 ( 4.1A)
 1.33A 5kbwB-1yniA:
undetectable		 5kbwB-1yniA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		4 / 8 ILE A  62
LEU A 149
ALA A 130
LEU A 132
 None
 0.86A 5y7pE-1yniA:
undetectable		 5y7pE-1yniA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)		 1yni SUCCINYLARGININE
DIHYDROLASE
(Escherichia
coli) 		5 / 12 ARG A  30
ALA A  27
GLY A  24
SER A 207
VAL A 300
 None
 1.31A 6clxA-1yniA:
undetectable		 6clxA-1yniA:
25.90