SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ynq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_A_FLPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		5 / 12 VAL A 270
VAL A 195
TYR A  51
GLY A 256
ALA A 255
 None
None
SO4  A 300 ( 4.9A)
SO4  A 300 (-3.8A)
SO4  A 300 (-4.0A)
 0.87A 1eqhA-1ynqA:
undetectable		 1eqhA-1ynqA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		5 / 12 VAL A 270
VAL A 195
TYR A  51
GLY A 256
ALA A 255
 None
None
SO4  A 300 ( 4.9A)
SO4  A 300 (-3.8A)
SO4  A 300 (-4.0A)
 0.87A 1eqhB-1ynqA:
undetectable		 1eqhB-1ynqA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		5 / 12 LEU A 239
LEU A 241
ALA A 257
ALA A 255
LEU A 204
 None
None
None
SO4  A 300 (-4.0A)
None
 0.94A 1kt5A-1ynqA:
undetectable		 1kt5A-1ynqA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		6 / 12 LEU A  11
VAL A  60
LEU A  64
LEU A  45
ILE A 113
LEU A 115
 None
 1.50A 1mx1D-1ynqA:
undetectable		 1mx1D-1ynqA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		4 / 6 TYR A 243
GLU A 180
PRO A 179
VAL A 195
 None
 1.25A 1q13A-1ynqA:
23.9		 1q13A-1ynqA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		4 / 6 TYR A 243
GLU A 180
PRO A 179
VAL A 250
 None
 1.11A 1q13A-1ynqA:
23.9		 1q13A-1ynqA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		3 / 3 GLY A  54
ASP A  49
ASN A  56
 None
 0.54A 1vq1A-1ynqA:
undetectable		 1vq1A-1ynqA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		3 / 3 GLN A 117
HIS A 119
ARG A 196
 None
 1.10A 1zlqA-1ynqA:
undetectable		 1zlqA-1ynqA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGZ_D_COCD401_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		4 / 6 TYR A 292
TYR A 172
GLN A 187
ILE A 186
 None
None
SO4  A 306 ( 4.8A)
None
 1.37A 2pgzD-1ynqA:
undetectable
2pgzE-1ynqA:
undetectable		 2pgzD-1ynqA:
20.37
2pgzE-1ynqA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		4 / 8 GLY A 120
GLY A 121
ILE A 156
SER A 149
 SO4  A 303 ( 4.1A)
None
None
None
 0.70A 3d41A-1ynqA:
undetectable		 3d41A-1ynqA:
26.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		5 / 9 ASP A  46
ALA A  48
ASP A  49
LEU A 118
VAL A 194
 None
 1.21A 3em4B-1ynqA:
undetectable		 3em4B-1ynqA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		5 / 12 VAL A 270
VAL A 195
TYR A  51
GLY A 256
ALA A 255
 None
None
SO4  A 300 ( 4.9A)
SO4  A 300 (-3.8A)
SO4  A 300 (-4.0A)
 1.01A 3hs6A-1ynqA:
undetectable		 3hs6A-1ynqA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8W_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		5 / 12 VAL A 270
VAL A 195
TYR A  51
GLY A 256
ALA A 255
 None
None
SO4  A 300 ( 4.9A)
SO4  A 300 (-3.8A)
SO4  A 300 (-4.0A)
 0.90A 3n8wA-1ynqA:
undetectable		 3n8wA-1ynqA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		5 / 12 VAL A 270
VAL A 195
TYR A  51
GLY A 256
ALA A 255
 None
None
SO4  A 300 ( 4.9A)
SO4  A 300 (-3.8A)
SO4  A 300 (-4.0A)
 0.84A 3n8zA-1ynqA:
undetectable		 3n8zA-1ynqA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		5 / 12 VAL A 270
VAL A 195
TYR A  51
GLY A 256
ALA A 255
 None
None
SO4  A 300 ( 4.9A)
SO4  A 300 (-3.8A)
SO4  A 300 (-4.0A)
 1.02A 3pghC-1ynqA:
undetectable		 3pghC-1ynqA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_A_FLRA700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		5 / 12 VAL A 270
VAL A 195
TYR A  51
GLY A 256
ALA A 255
 None
None
SO4  A 300 ( 4.9A)
SO4  A 300 (-3.8A)
SO4  A 300 (-4.0A)
 0.95A 3rr3A-1ynqA:
undetectable		 3rr3A-1ynqA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_B_FLRB700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		5 / 12 VAL A 270
VAL A 195
TYR A  51
GLY A 256
ALA A 255
 None
None
SO4  A 300 ( 4.9A)
SO4  A 300 (-3.8A)
SO4  A 300 (-4.0A)
 0.95A 3rr3B-1ynqA:
undetectable		 3rr3B-1ynqA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_C_FLRC700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		5 / 12 VAL A 270
VAL A 195
TYR A  51
GLY A 256
ALA A 255
 None
None
SO4  A 300 ( 4.9A)
SO4  A 300 (-3.8A)
SO4  A 300 (-4.0A)
 0.95A 3rr3C-1ynqA:
undetectable		 3rr3C-1ynqA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_D_FLRD700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		5 / 12 VAL A 270
VAL A 195
TYR A  51
GLY A 256
ALA A 255
 None
None
SO4  A 300 ( 4.9A)
SO4  A 300 (-3.8A)
SO4  A 300 (-4.0A)
 0.95A 3rr3D-1ynqA:
undetectable		 3rr3D-1ynqA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		4 / 8 SER A 163
ILE A 165
ILE A 186
ILE A 156
 None
 0.94A 4dtaB-1ynqA:
undetectable		 4dtaB-1ynqA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		4 / 4 LEU A 230
PRO A 231
LEU A 239
ILE A 174
 None
 0.98A 4f4dB-1ynqA:
undetectable		 4f4dB-1ynqA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		4 / 8 SER A 163
LEU A 137
ALA A 133
THR A 130
 None
 0.92A 4ikjA-1ynqA:
undetectable
4ikjB-1ynqA:
undetectable		 4ikjA-1ynqA:
17.24
4ikjB-1ynqA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		4 / 8 LEU A 137
ALA A 133
THR A 130
SER A 163
 None
 0.92A 4ikkA-1ynqA:
undetectable
4ikkB-1ynqA:
undetectable		 4ikkA-1ynqA:
17.24
4ikkB-1ynqA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		4 / 5 TYR A 243
ARG A 280
ASP A 248
VAL A  13
 None
SO4  A 306 (-2.6A)
SO4  A 306 (-3.2A)
None
 1.17A 4nkvB-1ynqA:
0.0		 4nkvB-1ynqA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		4 / 5 THR A  47
THR A  75
ASP A  46
TYR A  44
 None
 1.36A 4oltB-1ynqA:
undetectable		 4oltB-1ynqA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		3 / 3 GLN A 294
HIS A 295
ARG A 152
 None
SO4  A 304 (-3.7A)
SO4  A 302 ( 3.5A)
 1.30A 4qyqA-1ynqA:
undetectable		 4qyqA-1ynqA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		4 / 8 ILE A 186
SER A   9
LEU A 115
ILE A 165
 None
 0.76A 4xtaB-1ynqA:
undetectable		 4xtaB-1ynqA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		3 / 3 VAL A 166
TYR A 146
GLN A 117
 None
 0.71A 5qgkA-1ynqA:
undetectable		 5qgkA-1ynqA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1ynq OXIDOREDUCTASE
(Bacillus
halodurans) 		3 / 3 VAL A 166
TYR A 146
GLN A 117
 None
 0.72A 5qgrA-1ynqA:
undetectable		 5qgrA-1ynqA:
21.78