SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ynt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 1ynt PROTEIN L
(Finegoldia
magna) 		3 / 3 ASN E 873
PHE E 839
TYR E 851
 None
 0.86A 4u15A-1yntE:
undetectable		 4u15A-1yntE:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 1ynt MAJOR SURFACE
ANTIGEN P30
(Toxoplasma
gondii) 		5 / 12 ALA F2046
GLY F2083
THR F2082
THR F2040
LEU F2039
 None
 0.95A 5ybbA-1yntF:
undetectable		 5ybbA-1yntF:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 1ynt MAJOR SURFACE
ANTIGEN P30
(Toxoplasma
gondii) 		4 / 7 ASN F2028
TRP F2080
GLU F2100
ARG F2141
 None
 1.15A 6b8kA-1yntF:
undetectable		 6b8kA-1yntF:
15.77