SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yo6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 1yo6 PUTATIVE CARBONYL
REDUCTASE SNIFFER
(Caenorhabditis
elegans) 		3 / 3 ASP A 192
ASP A 138
ASP A 189
 None
 0.59A 1eizA-1yo6A:
9.7		 1eizA-1yo6A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 1yo6 PUTATIVE CARBONYL
REDUCTASE SNIFFER
(Caenorhabditis
elegans) 		3 / 3 ASP A 192
ASP A 138
ASP A 189
 None
 0.60A 1ej0A-1yo6A:
9.6		 1ej0A-1yo6A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 1yo6 PUTATIVE CARBONYL
REDUCTASE SNIFFER
(Caenorhabditis
elegans) 		4 / 6 LEU A  23
VAL A   8
ILE A  86
ILE A 226
 None
 0.74A 2piwA-1yo6A:
undetectable		 2piwA-1yo6A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1yo6 PUTATIVE CARBONYL
REDUCTASE SNIFFER
(Caenorhabditis
elegans) 		3 / 3 ASP A 192
ASP A 138
ASP A 189
 None
 0.67A 3douA-1yo6A:
9.5		 3douA-1yo6A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 1yo6 PUTATIVE CARBONYL
REDUCTASE SNIFFER
(Caenorhabditis
elegans) 		4 / 8 SER A 152
LEU A 154
ASP A 159
ARG A 173
 None
 1.05A 4umjA-1yo6A:
undetectable		 4umjA-1yo6A:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1yo6 PUTATIVE CARBONYL
REDUCTASE SNIFFER
(Caenorhabditis
elegans) 		5 / 12 ILE A  15
ALA A  11
LEU A  23
ILE A 148
ILE A 150
 None
 1.00A 4x5jA-1yo6A:
undetectable		 4x5jA-1yo6A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 1yo6 PUTATIVE CARBONYL
REDUCTASE SNIFFER
(Caenorhabditis
elegans) 		3 / 3 LEU A 225
ASP A  26
ILE A  32
 None
 0.63A 6dh0B-1yo6A:
undetectable		 6dh0B-1yo6A:
14.46