SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yo7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 1yo7 REGULATORY PROTEIN
ROP
(Escherichia
coli) 		5 / 12 LEU A 111
LEU A 114
ASN A 115
LEU A 117
ALA A 118
 None
 0.90A 1ya3C-1yo7A:
undetectable		 1ya3C-1yo7A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 1yo7 REGULATORY PROTEIN
ROP
(Escherichia
coli) 		5 / 12 LEU A 111
LEU A 114
ASN A 115
LEU A 117
ALA A 118
 None
 0.87A 4fn9A-1yo7A:
undetectable		 4fn9A-1yo7A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 1yo7 REGULATORY PROTEIN
ROP
(Escherichia
coli) 		5 / 12 LEU A 111
LEU A 114
ASN A 115
LEU A 117
ALA A 118
 None
 0.91A 4fn9B-1yo7A:
undetectable		 4fn9B-1yo7A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 1yo7 REGULATORY PROTEIN
ROP
(Escherichia
coli) 		5 / 12 LEU A 111
LEU A 114
ASN A 115
LEU A 117
ALA A 118
 None
 0.90A 4ltwA-1yo7A:
undetectable		 4ltwA-1yo7A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE0_A_XINA401_2
(AP2-ASSOCIATED
PROTEIN KINASE 1)		 1yo7 REGULATORY PROTEIN
ROP
(Escherichia
coli) 		4 / 5 LEU A 117
MET A  11
CYH A  52
CYH A  69
 None
 1.49A 5te0A-1yo7A:
undetectable		 5te0A-1yo7A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 1yo7 REGULATORY PROTEIN
ROP
(Escherichia
coli) 		5 / 12 ILE A  68
LEU A  53
ILE A  15
LEU A 111
THR A 107
 None
 1.32A 5tiwB-1yo7A:
undetectable		 5tiwB-1yo7A:
20.24