SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yob'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 1yob FLAVODOXIN 2
(Azotobacter
vinelandii) 		5 / 7 THR A  11
THR A  56
GLY A  97
ASP A  98
TYR A 102
 FMN  A1200 (-3.5A)
FMN  A1200 (-3.7A)
FMN  A1200 (-3.3A)
None
FMN  A1200 (-3.4A)
 0.53A 1bu5A-1yobA:
18.2		 1bu5A-1yobA:
28.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 1yob FLAVODOXIN 2
(Azotobacter
vinelandii) 		5 / 8 THR A  11
THR A  56
GLY A  97
ASP A  98
TYR A 102
 FMN  A1200 (-3.5A)
FMN  A1200 (-3.7A)
FMN  A1200 (-3.3A)
None
FMN  A1200 (-3.4A)
 0.49A 1bu5B-1yobA:
18.0		 1bu5B-1yobA:
28.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 1yob FLAVODOXIN 2
(Azotobacter
vinelandii) 		3 / 3 VAL A 147
TRP A 128
TRP A 167
 None
 1.21A 1c4dA-1yobA:
undetectable
1c4dB-1yobA:
undetectable		 1c4dA-1yobA:
15.00
1c4dB-1yobA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 1yob FLAVODOXIN 2
(Azotobacter
vinelandii) 		5 / 9 LEU A 168
ILE A 171
LEU A 151
GLY A 148
ALA A  92
 None
 0.78A 1e7aA-1yobA:
undetectable		 1e7aA-1yobA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQW_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN)		 1yob FLAVODOXIN 2
(Azotobacter
vinelandii) 		5 / 12 PHE A 117
ILE A  81
THR A  56
THR A  54
LEU A  78
 None
None
FMN  A1200 (-3.7A)
None
None
 1.30A 1kqwA-1yobA:
undetectable		 1kqwA-1yobA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 1yob FLAVODOXIN 2
(Azotobacter
vinelandii) 		3 / 3 PHE A  44
LEU A  50
MET A  30
 None
 0.83A 1mx1D-1yobA:
2.0		 1mx1D-1yobA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 1yob FLAVODOXIN 2
(Azotobacter
vinelandii) 		3 / 3 ALA A 109
GLY A  53
SER A  73
 None
 0.52A 2ivuA-1yobA:
undetectable		 2ivuA-1yobA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 1yob FLAVODOXIN 2
(Azotobacter
vinelandii) 		4 / 7 PRO A  63
THR A  54
PRO A  55
GLU A 112
 None
None
FMN  A1200 (-4.2A)
None
 1.03A 2v2gA-1yobA:
undetectable
2v2gB-1yobA:
undetectable		 2v2gA-1yobA:
20.78
2v2gB-1yobA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 1yob FLAVODOXIN 2
(Azotobacter
vinelandii) 		4 / 7 THR A  54
PRO A  55
GLU A 112
PRO A  63
 None
FMN  A1200 (-4.2A)
None
None
 0.99A 2v2gC-1yobA:
undetectable
2v2gD-1yobA:
undetectable		 2v2gC-1yobA:
20.78
2v2gD-1yobA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 1yob FLAVODOXIN 2
(Azotobacter
vinelandii) 		4 / 8 THR A  54
PRO A  55
GLU A 112
PRO A  63
 None
FMN  A1200 (-4.2A)
None
None
 0.95A 2v32A-1yobA:
undetectable
2v32B-1yobA:
undetectable		 2v32A-1yobA:
20.78
2v32B-1yobA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 1yob FLAVODOXIN 2
(Azotobacter
vinelandii) 		4 / 8 PRO A  63
THR A  54
PRO A  55
GLU A 112
 None
None
FMN  A1200 (-4.2A)
None
 1.00A 2v32A-1yobA:
undetectable
2v32B-1yobA:
undetectable		 2v32A-1yobA:
20.78
2v32B-1yobA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1yob FLAVODOXIN 2
(Azotobacter
vinelandii) 		5 / 12 LEU A 168
GLY A 126
SER A 127
ILE A  51
LEU A 177
 None
SO4  A 702 (-3.5A)
SO4  A 702 (-2.9A)
None
None
 0.93A 3cjtO-1yobA:
undetectable		 3cjtO-1yobA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 1yob FLAVODOXIN 2
(Azotobacter
vinelandii) 		4 / 6 GLY A  64
THR A  54
GLU A  76
GLU A  82
 None
 0.93A 3fpjA-1yobA:
undetectable		 3fpjA-1yobA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 1yob FLAVODOXIN 2
(Azotobacter
vinelandii) 		5 / 12 LEU A  62
VAL A  36
GLY A   8
PHE A  77
LEU A  78
 None
 1.17A 3mecA-1yobA:
undetectable		 3mecA-1yobA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 1yob FLAVODOXIN 2
(Azotobacter
vinelandii) 		5 / 12 LEU A  62
VAL A  36
GLY A   8
PHE A  77
LEU A  78
 None
 1.18A 3medA-1yobA:
undetectable
3medB-1yobA:
undetectable		 3medA-1yobA:
17.80
3medB-1yobA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 1yob FLAVODOXIN 2
(Azotobacter
vinelandii) 		4 / 6 GLN A  46
TYR A  47
PHE A   6
LEU A  34
 None
 1.30A 3tgvD-1yobA:
undetectable		 3tgvD-1yobA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 1yob FLAVODOXIN 2
(Azotobacter
vinelandii) 		4 / 8 SER A 137
GLY A  97
THR A  56
GLY A 111
 None
FMN  A1200 (-3.3A)
FMN  A1200 (-3.7A)
None
 0.69A 4fo4B-1yobA:
undetectable		 4fo4B-1yobA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 1yob FLAVODOXIN 2
(Azotobacter
vinelandii) 		5 / 12 PHE A 117
ILE A  81
THR A  56
THR A  54
LEU A  78
 None
None
FMN  A1200 (-3.7A)
None
None
 1.25A 4qzuA-1yobA:
undetectable		 4qzuA-1yobA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 1yob FLAVODOXIN 2
(Azotobacter
vinelandii) 		5 / 12 PHE A 117
ILE A  81
THR A  56
THR A  54
LEU A  78
 None
None
FMN  A1200 (-3.7A)
None
None
 1.11A 4qzuC-1yobA:
undetectable		 4qzuC-1yobA:
18.72