SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yoc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1yoc HYPOTHETICAL PROTEIN
PA1835
(Pseudomonas
aeruginosa) 		4 / 8 LEU A  53
VAL A  52
VAL A 128
VAL A 103
 None
 0.95A 1iwiA-1yocA:
undetectable		 1iwiA-1yocA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 1yoc HYPOTHETICAL PROTEIN
PA1835
(Pseudomonas
aeruginosa) 		4 / 6 PRO A  32
PHE A  46
GLU A  43
VAL A 106
 None
 1.37A 1l2iB-1yocA:
undetectable		 1l2iB-1yocA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1yoc HYPOTHETICAL PROTEIN
PA1835
(Pseudomonas
aeruginosa) 		4 / 5 PHE A  34
PHE A  16
MET A   4
SER A   2
 None
 1.24A 1wrkB-1yocA:
undetectable		 1wrkB-1yocA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1yoc HYPOTHETICAL PROTEIN
PA1835
(Pseudomonas
aeruginosa) 		4 / 7 PHE A  34
PHE A  16
MET A   4
SER A   2
 None
 0.92A 1wrlA-1yocA:
undetectable
1wrlB-1yocA:
undetectable		 1wrlA-1yocA:
22.73
1wrlB-1yocA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1yoc HYPOTHETICAL PROTEIN
PA1835
(Pseudomonas
aeruginosa) 		4 / 5 PHE A  34
PHE A  16
MET A   4
SER A   2
 None
 1.06A 1wrlC-1yocA:
undetectable		 1wrlC-1yocA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_C_GBNC1414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 1yoc HYPOTHETICAL PROTEIN
PA1835
(Pseudomonas
aeruginosa) 		5 / 8 GLU A  69
GLY A  73
THR A  74
ALA A  71
ALA A  72
 None
 1.36A 2ej3C-1yocA:
undetectable		 2ej3C-1yocA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1yoc HYPOTHETICAL PROTEIN
PA1835
(Pseudomonas
aeruginosa) 		4 / 7 TYR A  95
PHE A 134
ALA A  67
ALA A 136
 None
 1.17A 2vcvA-1yocA:
undetectable		 2vcvA-1yocA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1yoc HYPOTHETICAL PROTEIN
PA1835
(Pseudomonas
aeruginosa) 		4 / 7 LEU A  70
PRO A  88
VAL A 122
MET A  91
 None
 1.26A 4klrA-1yocA:
undetectable		 4klrA-1yocA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 1yoc HYPOTHETICAL PROTEIN
PA1835
(Pseudomonas
aeruginosa) 		3 / 3 VAL A  35
THR A  45
ARG A 104
 None
 0.72A 5b2sB-1yocA:
undetectable		 5b2sB-1yocA:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 1yoc HYPOTHETICAL PROTEIN
PA1835
(Pseudomonas
aeruginosa) 		3 / 3 VAL A  35
THR A  45
ARG A 104
 None
 0.73A 5b2tB-1yocA:
undetectable		 5b2tB-1yocA:
7.23