SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yox'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_C_T44C128_1
(TRANSTHYRETIN)		 1yox HYPOTHETICAL PROTEIN
PA3696
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 149
ALA A 120
LEU A 154
THR A 124
VAL A 126
 None
 1.26A 1ictA-1yoxA:
undetectable
1ictC-1yoxA:
undetectable		 1ictA-1yoxA:
20.31
1ictC-1yoxA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1yox HYPOTHETICAL PROTEIN
PA3696
(Pseudomonas
aeruginosa) 		3 / 3 GLY A 170
GLY A 216
GLY A 214
 None
 0.34A 3bogC-1yoxA:
undetectable		 3bogC-1yoxA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 1yox HYPOTHETICAL PROTEIN
PA3696
(Pseudomonas
aeruginosa) 		5 / 8 ALA A 100
VAL A 101
ASP A 102
LEU A 103
LEU A   6
 None
 1.15A 3roxA-1yoxA:
undetectable		 3roxA-1yoxA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1yox HYPOTHETICAL PROTEIN
PA3696
(Pseudomonas
aeruginosa) 		4 / 8 LEU A 110
TRP A 219
VAL A 101
VAL A 157
 None
 1.00A 4em2A-1yoxA:
undetectable		 4em2A-1yoxA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1yox HYPOTHETICAL PROTEIN
PA3696
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 123
GLY A 153
GLU A   5
LEU A 154
 None
 0.87A 4fgzA-1yoxA:
undetectable		 4fgzA-1yoxA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1yox HYPOTHETICAL PROTEIN
PA3696
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 123
GLY A 153
GLU A   5
LEU A 154
 None
 0.88A 4fgzB-1yoxA:
undetectable		 4fgzB-1yoxA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 1yox HYPOTHETICAL PROTEIN
PA3696
(Pseudomonas
aeruginosa) 		5 / 9 THR A 124
LEU A 149
ALA A 120
LEU A 118
PHE A 117
 None
 1.38A 4ltwA-1yoxA:
undetectable		 4ltwA-1yoxA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 1yox HYPOTHETICAL PROTEIN
PA3696
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 178
TYR A  94
SER A 226
SER A 116
 None
 1.03A 4wryA-1yoxA:
undetectable		 4wryA-1yoxA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 1yox HYPOTHETICAL PROTEIN
PA3696
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 178
TYR A  94
SER A 226
SER A 116
 None
 1.00A 4wrzA-1yoxA:
undetectable		 4wrzA-1yoxA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 1yox HYPOTHETICAL PROTEIN
PA3696
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 178
TYR A  94
SER A 226
SER A 116
 None
 0.93A 4ws1A-1yoxA:
undetectable		 4ws1A-1yoxA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YSI_A_NCAA1001_0
(UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA)		 1yox HYPOTHETICAL PROTEIN
PA3696
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 109
GLY A 108
THR A 184
VAL A 106
 None
 0.99A 5ysiA-1yoxA:
0.0		 5ysiA-1yoxA:
22.09