SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yoz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1yoz HYPOTHETICAL PROTEIN
AF0941
(Archaeoglobus
fulgidus) 		5 / 10 TYR A 116
LEU A  55
ILE A  54
ALA A 114
PHE A  72
 None
 1.06A 1xp0A-1yozA:
undetectable		 1xp0A-1yozA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1yoz HYPOTHETICAL PROTEIN
AF0941
(Archaeoglobus
fulgidus) 		3 / 3 ASN A  71
ASP A  50
ARG A  26
 None
 0.76A 3k13A-1yozA:
undetectable		 3k13A-1yozA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1yoz HYPOTHETICAL PROTEIN
AF0941
(Archaeoglobus
fulgidus) 		3 / 3 ASN A  71
ASP A  50
ARG A  89
 None
 0.92A 3k13C-1yozA:
undetectable		 3k13C-1yozA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 1yoz HYPOTHETICAL PROTEIN
AF0941
(Archaeoglobus
fulgidus) 		4 / 7 THR A  77
ASN A  15
TYR A  13
LEU A  18
 None
 0.99A 4awuA-1yozA:
undetectable		 4awuA-1yozA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1yoz HYPOTHETICAL PROTEIN
AF0941
(Archaeoglobus
fulgidus) 		5 / 12 ILE A  43
ALA A  34
LEU A  38
ILE A  24
PHE A  47
 None
 1.12A 4lnwA-1yozA:
undetectable		 4lnwA-1yozA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1yoz HYPOTHETICAL PROTEIN
AF0941
(Archaeoglobus
fulgidus) 		5 / 12 ILE A  43
ALA A  34
LEU A  38
ILE A  24
PHE A  47
 None
 1.12A 4lnxA-1yozA:
undetectable		 4lnxA-1yozA:
18.91