SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yp1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1872_0
(FPRA)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 5 SER A  54
ASN A  92
ALA A  95
ASP A  93
 None
 1.40A 1lqtA-1yp1A:
3.9
1lqtB-1yp1A:
3.9		 1lqtA-1yp1A:
16.74
1lqtB-1yp1A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1429_0
(FPRA)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 5 SER A  54
ASN A  92
ALA A  95
ASP A  93
 None
 1.40A 1lquA-1yp1A:
3.7
1lquB-1yp1A:
3.7		 1lquA-1yp1A:
16.74
1lquB-1yp1A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.32A 1os2A-1yp1A:
9.3		 1os2A-1yp1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.28A 1os2D-1yp1A:
11.1		 1os2D-1yp1A:
21.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R55_A_097A518_1
(ADAM 33)		 1yp1 FII
(Deinagkistrodon
acutus) 		6 / 10 ALA A 106
VAL A 108
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
None
ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.46A 1r55A-1yp1A:
30.6		 1r55A-1yp1A:
33.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.23A 1uttA-1yp1A:
11.4		 1uttA-1yp1A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.30A 1utzA-1yp1A:
11.3		 1utzA-1yp1A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.26A 1utzB-1yp1A:
11.3		 1utzB-1yp1A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 6 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.27A 1y93A-1yp1A:
11.5		 1y93A-1yp1A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1yp1 FII
(Deinagkistrodon
acutus) 		3 / 3 HIS A 152
HIS A 146
HIS A 142
 ZN  A 999 (-3.2A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.3A)
 0.71A 2einN-1yp1A:
undetectable		 2einN-1yp1A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.23A 2hu6A-1yp1A:
11.4		 2hu6A-1yp1A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 8 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.20A 2jihB-1yp1A:
25.8		 2jihB-1yp1A:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 6 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.35A 2ow9A-1yp1A:
11.1		 2ow9A-1yp1A:
25.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.31A 2ow9B-1yp1A:
10.9		 2ow9B-1yp1A:
25.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.34A 2ozrC-1yp1A:
10.7		 2ozrC-1yp1A:
25.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.35A 2ozrD-1yp1A:
10.8		 2ozrD-1yp1A:
25.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.32A 2ozrE-1yp1A:
10.9		 2ozrE-1yp1A:
25.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 1yp1 FII
(Deinagkistrodon
acutus) 		3 / 3 HIS A 142
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.28A 2ozrF-1yp1A:
10.7		 2ozrF-1yp1A:
25.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1yp1 FII
(Deinagkistrodon
acutus) 		3 / 3 HIS A 152
HIS A 146
HIS A 142
 ZN  A 999 (-3.2A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.3A)
 0.75A 3bvdA-1yp1A:
undetectable		 3bvdA-1yp1A:
16.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1yp1 FII
(Deinagkistrodon
acutus) 		5 / 9 HIS A 142
GLU A 143
HIS A 146
HIS A 152
LEU A 169
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
None
 0.84A 3hy7A-1yp1A:
26.5		 3hy7A-1yp1A:
30.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1yp1 FII
(Deinagkistrodon
acutus) 		5 / 9 HIS A 142
GLU A 143
HIS A 146
HIS A 152
LEU A 169
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
None
 0.64A 3hy7B-1yp1A:
26.5		 3hy7B-1yp1A:
30.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.29A 3kecA-1yp1A:
11.0		 3kecA-1yp1A:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.27A 3likA-1yp1A:
11.4		 3likA-1yp1A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.26A 3lilA-1yp1A:
11.4		 3lilA-1yp1A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.27A 3ljgA-1yp1A:
11.5		 3ljgA-1yp1A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.25A 3lkaA-1yp1A:
11.4		 3lkaA-1yp1A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1yp1 FII
(Deinagkistrodon
acutus) 		3 / 3 HIS A 152
HIS A 146
HIS A 142
 ZN  A 999 (-3.2A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.3A)
 0.79A 3s33A-1yp1A:
undetectable		 3s33A-1yp1A:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1yp1 FII
(Deinagkistrodon
acutus) 		3 / 3 HIS A 152
HIS A 146
HIS A 142
 ZN  A 999 (-3.2A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.3A)
 0.75A 3s38A-1yp1A:
0.0		 3s38A-1yp1A:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1yp1 FII
(Deinagkistrodon
acutus) 		3 / 3 HIS A 152
HIS A 146
HIS A 142
 ZN  A 999 (-3.2A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.3A)
 0.80A 3s3aA-1yp1A:
undetectable		 3s3aA-1yp1A:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1yp1 FII
(Deinagkistrodon
acutus) 		3 / 3 HIS A 152
HIS A 146
HIS A 142
 ZN  A 999 (-3.2A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.3A)
 0.81A 3s3bA-1yp1A:
undetectable		 3s3bA-1yp1A:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 1yp1 FII
(Deinagkistrodon
acutus) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 197
 None
 1.09A 3ut5D-1yp1A:
undetectable		 3ut5D-1yp1A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 1yp1 FII
(Deinagkistrodon
acutus) 		5 / 12 LEU A 144
ASN A  94
ALA A  95
MET A  40
LEU A  53
 None
 1.49A 3vhuA-1yp1A:
undetectable		 3vhuA-1yp1A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1yp1 FII
(Deinagkistrodon
acutus) 		3 / 3 HIS A 152
HIS A 146
HIS A 142
 ZN  A 999 (-3.2A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.3A)
 0.74A 3wg7A-1yp1A:
undetectable		 3wg7A-1yp1A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1yp1 FII
(Deinagkistrodon
acutus) 		3 / 3 HIS A 152
HIS A 146
HIS A 142
 ZN  A 999 (-3.2A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.3A)
 0.73A 3x2qN-1yp1A:
undetectable		 3x2qN-1yp1A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 6 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.41A 4a7bA-1yp1A:
10.7		 4a7bA-1yp1A:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8W_I_MTXI301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 1yp1 FII
(Deinagkistrodon
acutus) 		5 / 9 PHE A 129
GLY A  71
GLY A 109
LEU A 110
GLN A  96
 None
 1.28A 4l8wI-1yp1A:
0.6		 4l8wI-1yp1A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA602_1
(SERUM ALBUMIN)		 1yp1 FII
(Deinagkistrodon
acutus) 		5 / 9 PHE A 112
ALA A 123
ALA A  95
SER A  76
LEU A  75
 None
 1.24A 4or0A-1yp1A:
undetectable		 4or0A-1yp1A:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 1yp1 FII
(Deinagkistrodon
acutus) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 197
 None
 0.99A 4x1iD-1yp1A:
undetectable		 4x1iD-1yp1A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 1yp1 FII
(Deinagkistrodon
acutus) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 197
 None
 0.93A 4x1yD-1yp1A:
undetectable		 4x1yD-1yp1A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 1yp1 FII
(Deinagkistrodon
acutus) 		5 / 11 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 197
 None
 0.98A 4x20D-1yp1A:
undetectable		 4x20D-1yp1A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 4 LEU A 169
ILE A 164
HIS A 142
VAL A 138
 None
None
ZN  A 999 (-3.3A)
None
 1.20A 4xyzA-1yp1A:
undetectable		 4xyzA-1yp1A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 8 TYR A  22
ASP A 128
ILE A  56
ILE A 126
 None
 0.82A 5hw8H-1yp1A:
undetectable		 5hw8H-1yp1A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 1yp1 FII
(Deinagkistrodon
acutus) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 197
 None
 0.98A 5itzB-1yp1A:
undetectable		 5itzB-1yp1A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1yp1 FII
(Deinagkistrodon
acutus) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 197
 None
 1.02A 5mioB-1yp1A:
undetectable		 5mioB-1yp1A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.24A 5n5jA-1yp1A:
11.5		 5n5jA-1yp1A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.3A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.2A)
 0.27A 5n5kA-1yp1A:
11.5		 5n5kA-1yp1A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1yp1 FII
(Deinagkistrodon
acutus) 		3 / 3 HIS A 152
HIS A 146
HIS A 142
 ZN  A 999 (-3.2A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.3A)
 0.73A 5w97a-1yp1A:
undetectable		 5w97a-1yp1A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1yp1 FII
(Deinagkistrodon
acutus) 		3 / 3 HIS A 152
HIS A 146
HIS A 142
 ZN  A 999 (-3.2A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.3A)
 0.67A 5x1fN-1yp1A:
undetectable		 5x1fN-1yp1A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1yp1 FII
(Deinagkistrodon
acutus) 		3 / 3 HIS A 152
HIS A 146
HIS A 142
 ZN  A 999 (-3.2A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.3A)
 0.77A 5z85N-1yp1A:
undetectable		 5z85N-1yp1A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1yp1 FII
(Deinagkistrodon
acutus) 		3 / 3 HIS A 152
HIS A 146
HIS A 142
 ZN  A 999 (-3.2A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.3A)
 0.79A 5z86N-1yp1A:
undetectable		 5z86N-1yp1A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1yp1 FII
(Deinagkistrodon
acutus) 		3 / 3 HIS A 152
HIS A 146
HIS A 142
 ZN  A 999 (-3.2A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.3A)
 0.74A 5zcoN-1yp1A:
undetectable		 5zcoN-1yp1A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1yp1 FII
(Deinagkistrodon
acutus) 		3 / 3 HIS A 152
HIS A 146
HIS A 142
 ZN  A 999 (-3.2A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.3A)
 0.77A 5zcqN-1yp1A:
undetectable		 5zcqN-1yp1A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1yp1 FII
(Deinagkistrodon
acutus) 		3 / 3 HIS A 152
HIS A 146
HIS A 142
 ZN  A 999 (-3.2A)
ZN  A 999 (-3.4A)
ZN  A 999 (-3.3A)
 0.77A 6hu9m-1yp1A:
undetectable		 6hu9m-1yp1A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 4 ASP A 172
ILE A 132
PRO A 133
LEU A 135
 None
 1.16A 6mkeB-1yp1A:
undetectable		 6mkeB-1yp1A:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1yp1 FII
(Deinagkistrodon
acutus) 		4 / 4 ASP A 172
ILE A 132
PRO A 133
LEU A 135
 None
 1.24A 6mkeA-1yp1A:
undetectable		 6mkeA-1yp1A:
15.05