SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yp4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_A_T3A1_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 12 ILE A 415
ILE A 414
ALA A 359
LEU A 366
ILE A 355
 None
 1.10A 1bsxA-1yp4A:
undetectable		 1bsxA-1yp4A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_B_T3B2_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 12 ILE A 415
ILE A 414
ALA A 359
LEU A 366
ILE A 355
 None
 1.10A 1bsxB-1yp4A:
undetectable		 1bsxB-1yp4A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_1
(HIV-1 PROTEASE)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 12 GLY A 358
ALA A 359
ILE A 408
GLY A 409
ILE A 355
 None
 0.76A 1hxbA-1yp4A:
undetectable		 1hxbA-1yp4A:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 12 GLY A 231
HIS A 146
ILE A  55
LEU A  85
VAL A 102
 None
 1.08A 1r30B-1yp4A:
2.2		 1r30B-1yp4A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		3 / 3 ILE A  25
ILE A  70
THR A  74
 None
 0.56A 1rg7A-1yp4A:
undetectable		 1rg7A-1yp4A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_2
(POL POLYPROTEIN)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		4 / 7 ALA A 143
ASP A 145
GLY A 255
ILE A 259
 ADP  A 557 (-3.5A)
ADP  A 557 (-3.2A)
ADP  A 557 (-3.6A)
None
 0.81A 1t7iB-1yp4A:
undetectable		 1t7iB-1yp4A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_2
(POL POLYPROTEIN)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		4 / 7 ALA A 143
ASP A 145
GLY A 255
ILE A 259
 ADP  A 557 (-3.5A)
ADP  A 557 (-3.2A)
ADP  A 557 (-3.6A)
None
 0.83A 1t7jB-1yp4A:
undetectable		 1t7jB-1yp4A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 12 GLY A 358
ALA A 359
ILE A 408
GLY A 409
ILE A 355
 None
 0.77A 2avsA-1yp4A:
undetectable		 2avsA-1yp4A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 12 GLY A 358
ALA A 359
ILE A 408
GLY A 409
ILE A 355
 None
 0.79A 2avvA-1yp4A:
undetectable		 2avvA-1yp4A:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_1
(POL POLYPROTEIN)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 12 GLY A 358
ALA A 359
ILE A 408
GLY A 409
ILE A 355
 None
 0.76A 2avvD-1yp4A:
undetectable		 2avvD-1yp4A:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H79_A_T3A1_1
(THRA PROTEIN)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 12 ILE A 415
ILE A 414
ALA A 359
LEU A 366
ILE A 355
 None
 1.04A 2h79A-1yp4A:
undetectable		 2h79A-1yp4A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		4 / 8 LYS A 404
LYS A 441
ASP A 370
ALA A  79
 SO4  A1000 (-2.9A)
SO4  A1000 (-2.8A)
SO4  A1000 (-3.0A)
None
 1.40A 2rk8A-1yp4A:
undetectable		 2rk8A-1yp4A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		4 / 8 LYS A 441
SER A  80
ASP A 370
ALA A  45
 SO4  A1000 (-2.8A)
SO4  A1000 (-2.9A)
SO4  A1000 (-3.0A)
None
 0.88A 2rk8A-1yp4A:
undetectable		 2rk8A-1yp4A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_B_PPFB3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		4 / 7 LYS A 404
LYS A 441
SER A  80
ASP A 370
 SO4  A1000 (-2.9A)
SO4  A1000 (-2.8A)
SO4  A1000 (-2.9A)
SO4  A1000 (-3.0A)
 1.46A 2rk8B-1yp4A:
undetectable		 2rk8B-1yp4A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		4 / 7 ALA A 121
GLY A 119
ASP A 122
LEU A 244
 None
ADP  A 557 ( 4.6A)
None
None
 0.84A 2uyqA-1yp4A:
undetectable		 2uyqA-1yp4A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 12 ALA A  45
PRO A 114
GLY A  31
THR A  32
TYR A  35
 None
None
SO4  A1020 (-3.2A)
SO4  A1020 (-4.2A)
None
 1.03A 2zifB-1yp4A:
2.6		 2zifB-1yp4A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 12 GLY A 358
ALA A 359
ILE A 408
GLY A 409
ILE A 355
 None
 0.79A 3cyxB-1yp4A:
undetectable		 3cyxB-1yp4A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GP0_A_NILA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		4 / 7 ARG A  33
VAL A  72
LEU A 128
ILE A  25
 None
 0.96A 3gp0A-1yp4A:
undetectable		 3gp0A-1yp4A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 12 ILE A 415
ILE A 414
ALA A 359
LEU A 366
ILE A 355
 None
 1.04A 3gwsX-1yp4A:
undetectable		 3gwsX-1yp4A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 12 GLY A  49
PHE A 302
SER A 303
ILE A 281
LEU A  48
 None
 1.10A 3iv6C-1yp4A:
undetectable		 3iv6C-1yp4A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		3 / 3 PRO A 111
SER A  78
ASN A 113
 None
 0.89A 3lslG-1yp4A:
undetectable		 3lslG-1yp4A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 12 ALA A 443
ASP A 442
ILE A 391
VAL A 437
ILE A 402
 None
 1.12A 3n3iA-1yp4A:
undetectable		 3n3iA-1yp4A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		4 / 8 ALA A 143
ASP A 145
GLY A 255
ILE A 259
 ADP  A 557 (-3.5A)
ADP  A 557 (-3.2A)
ADP  A 557 (-3.6A)
None
 0.77A 3nu9A-1yp4A:
undetectable		 3nu9A-1yp4A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 11 TYR A 152
LEU A  63
ALA A  17
ILE A 156
PHE A 155
 None
 1.48A 3qelA-1yp4A:
undetectable
3qelB-1yp4A:
undetectable		 3qelA-1yp4A:
21.02
3qelB-1yp4A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_C_ACHC323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		4 / 8 GLU A 133
TYR A  71
LEU A 105
PHE A 131
 None
 0.96A 3rqwC-1yp4A:
undetectable
3rqwD-1yp4A:
undetectable		 3rqwC-1yp4A:
21.06
3rqwD-1yp4A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_J_ACHJ323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		4 / 8 GLU A 133
TYR A  71
LEU A 105
PHE A 131
 None
 0.94A 3rqwF-1yp4A:
undetectable
3rqwJ-1yp4A:
undetectable		 3rqwF-1yp4A:
21.06
3rqwJ-1yp4A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 12 PHE A 181
ILE A 259
GLY A 182
ALA A 228
ALA A 169
 None
 1.10A 3sudB-1yp4A:
undetectable		 3sudB-1yp4A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		3 / 3 PHE A 302
TYR A 305
LEU A 292
 None
 0.80A 3sueB-1yp4A:
undetectable		 3sueB-1yp4A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_1
(POL POLYPROTEIN)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 9 LEU A 318
ILE A 355
GLY A 390
ILE A 389
LEU A 351
 None
 1.00A 3u7sA-1yp4A:
undetectable		 3u7sA-1yp4A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		4 / 7 GLY A 390
GLY A 392
VAL A 387
CYH A 395
 None
 0.88A 4c5nA-1yp4A:
undetectable		 4c5nA-1yp4A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		4 / 8 VAL A  21
HIS A 159
ILE A 156
ALA A 164
 None
 1.00A 4eyzA-1yp4A:
undetectable		 4eyzA-1yp4A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		4 / 8 VAL A  21
HIS A 159
ILE A 156
ALA A 164
 None
 0.99A 4eyzB-1yp4A:
undetectable		 4eyzB-1yp4A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 12 LEU A  54
ASP A 145
VAL A  46
ALA A  30
THR A 283
 None
ADP  A 557 (-3.2A)
None
None
None
 1.49A 4iarA-1yp4A:
undetectable		 4iarA-1yp4A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTV_C_ADNC403_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 11 ASP A 403
SER A 353
ASP A 442
ILE A 389
ASP A 370
 None
None
None
None
SO4  A1000 (-3.0A)
 1.17A 4ktvC-1yp4A:
undetectable
4ktvD-1yp4A:
undetectable		 4ktvC-1yp4A:
23.06
4ktvD-1yp4A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		4 / 8 LEU A 130
TYR A  71
ILE A  24
VAL A 136
 None
 0.97A 4ma7A-1yp4A:
undetectable		 4ma7A-1yp4A:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PE5_B_QELB920_1
(GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 1
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 10 TYR A 152
LEU A  63
ALA A  17
ILE A 156
PHE A 155
 None
 1.47A 4pe5A-1yp4A:
undetectable
4pe5B-1yp4A:
1.2		 4pe5A-1yp4A:
21.81
4pe5B-1yp4A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PE5_C_QELC939_1
(GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 1
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 10 TYR A 152
LEU A  63
ALA A  17
ILE A 156
PHE A 155
 None
 1.46A 4pe5C-1yp4A:
1.4
4pe5D-1yp4A:
1.9		 4pe5C-1yp4A:
21.81
4pe5D-1yp4A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		4 / 7 VAL A 412
ILE A 402
ALA A 443
ILE A 401
 None
 0.76A 4uxqA-1yp4A:
undetectable		 4uxqA-1yp4A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 11 TYR A 152
LEU A  63
ALA A  17
ILE A 156
PHE A 155
 None
 1.50A 5ewjA-1yp4A:
undetectable
5ewjB-1yp4A:
undetectable		 5ewjA-1yp4A:
20.34
5ewjB-1yp4A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		3 / 3 LYS A 222
ASP A 218
ILE A 227
 None
 0.83A 5kc4E-1yp4A:
undetectable		 5kc4E-1yp4A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_A_P2EA1201_0
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		5 / 12 GLN A 270
THR A 167
VAL A 234
LEU A  13
ARG A 160
 None
 1.35A 6ak3A-1yp4A:
0.0		 6ak3A-1yp4A:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT
(Solanum
tuberosum) 		4 / 7 ASN A 291
ALA A 290
GLU A 285
LEU A 365
 None
 1.09A 6ci6A-1yp4A:
undetectable		 6ci6A-1yp4A:
10.23