SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ypo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 1ypo OXIDISED LOW DENSITY
LIPOPROTEIN
(LECTIN-LIKE)
RECEPTOR 1
(Homo
sapiens) 		4 / 8 PRO A 214
SER A 207
LEU A 206
LYS A 181
 None
 1.10A 3lsfH-1ypoA:
undetectable		 3lsfH-1ypoA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 1ypo OXIDISED LOW DENSITY
LIPOPROTEIN
(LECTIN-LIKE)
RECEPTOR 1
(Homo
sapiens) 		4 / 6 ALA A 253
LEU A 206
SER A 207
THR A 242
 None
 1.22A 4d7bB-1ypoA:
undetectable		 4d7bB-1ypoA:
20.13