SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yq8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FSL_A_NIOA145_1 (LEGHEMOGLOBIN A)	1yq8	MINOR CAPSID PROTEIN (Salmonella virus PRD1)	4 / 8	ILE A 332 PHE A 225 LEU A 327 VAL A 263	None	0.90A	1fslA-1yq8A: undetectable	1fslA-1yq8A: 23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PS9_A_SAMA670_1 (TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC)	1yq8	MINOR CAPSID PROTEIN (Salmonella virus PRD1)	4 / 6	TYR A 207 GLY A 212 THR A 211 LEU A 231	None	0.93A	3ps9A-1yq8A: undetectable	3ps9A-1yq8A: 13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUF_A_SUEA1201_1 (NS3 PROTEASE, NS4A PROTEIN)	1yq8	MINOR CAPSID PROTEIN (Salmonella virus PRD1)	5 / 12	GLY A 175 LEU A 203 GLY A 237 ALA A 337 ALA A 336	None	1.05A	3sufA-1yq8A: undetectable	3sufA-1yq8A: 23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TIX_B_OQRB302_0 (SULFOTRANSFERASE)	1yq8	MINOR CAPSID PROTEIN (Salmonella virus PRD1)	5 / 10	MET A 261 ILE A 332 LEU A 274 PHE A 225 SER A 319	None	1.42A	5tixB-1yq8A: undetectable	5tixB-1yq8A: 22.14

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FSL_A_NIOA145_1","LEGHEMOGLOBIN A","1yq8","MINOR CAPSID PROTEIN","Salmonella virus PRD1",4,"ILE A 332;PHE A 225;LEU A 327;VAL A 263","None","0.90A","1fslA-1yq8A:undetectable","1fslA-1yq8A:23.76"],["3PS9_A_SAMA670_1","TRNA 5-METHYLAMINOMETHYL-2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC","1yq8","MINOR CAPSID PROTEIN","Salmonella virus PRD1",4,"TYR A 207;GLY A 212;THR A 211;LEU A 231","None","0.93A","3ps9A-1yq8A:undetectable","3ps9A-1yq8A:13.89"],["3SUF_A_SUEA1201_1","NS3 PROTEASE, NS4A PROTEIN","1yq8","MINOR CAPSID PROTEIN","Salmonella virus PRD1",5,"GLY A 175;LEU A 203;GLY A 237;ALA A 337;ALA A 336","None","1.05A","3sufA-1yq8A:undetectable","3sufA-1yq8A:23.83"],["5TIX_B_OQRB302_0","SULFOTRANSFERASE","1yq8","MINOR CAPSID PROTEIN","Salmonella virus PRD1",5,"MET A 261;ILE A 332;LEU A 274;PHE A 225;SER A 319","None","1.42A","5tixB-1yq8A:undetectable","5tixB-1yq8A:22.14"]]