SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yqf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1yqf HYPOTHETICAL PROTEIN
LMAJ011689
(Leishmania
major) 		3 / 3 LEU A 151
VAL A 154
LEU A 158
 None
 0.39A 1mz9B-1yqfA:
undetectable		 1mz9B-1yqfA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 1yqf HYPOTHETICAL PROTEIN
LMAJ011689
(Leishmania
major) 		5 / 12 SER A  83
ILE A 104
ILE A  86
LEU A 109
VAL A  70
 None
 1.06A 2nnhA-1yqfA:
undetectable		 2nnhA-1yqfA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 1yqf HYPOTHETICAL PROTEIN
LMAJ011689
(Leishmania
major) 		3 / 3 THR A  74
SER A  73
TYR A  72
 None
 0.87A 5jsdA-1yqfA:
undetectable		 5jsdA-1yqfA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 1yqf HYPOTHETICAL PROTEIN
LMAJ011689
(Leishmania
major) 		3 / 3 THR A  74
SER A  73
TYR A  72
 None
 0.88A 5jsdB-1yqfA:
undetectable		 5jsdB-1yqfA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 1yqf HYPOTHETICAL PROTEIN
LMAJ011689
(Leishmania
major) 		3 / 3 THR A  74
SER A  73
TYR A  72
 None
 0.87A 5jsdC-1yqfA:
undetectable		 5jsdC-1yqfA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 1yqf HYPOTHETICAL PROTEIN
LMAJ011689
(Leishmania
major) 		3 / 3 THR A  74
SER A  73
TYR A  72
 None
 0.88A 5jseA-1yqfA:
undetectable		 5jseA-1yqfA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 1yqf HYPOTHETICAL PROTEIN
LMAJ011689
(Leishmania
major) 		3 / 3 THR A  74
SER A  73
TYR A  72
 None
 0.88A 5jseB-1yqfA:
undetectable		 5jseB-1yqfA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 1yqf HYPOTHETICAL PROTEIN
LMAJ011689
(Leishmania
major) 		3 / 3 THR A  74
SER A  73
TYR A  72
 None
 0.88A 5jseC-1yqfA:
undetectable		 5jseC-1yqfA:
15.30