SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ysj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_A_T3A1_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 12 ILE A  45
ILE A  56
ALA A 111
LEU A  38
ILE A 107
 None
 1.14A 1bsxA-1ysjA:
undetectable		 1bsxA-1ysjA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_B_T3B2_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 12 ILE A  45
ILE A  56
ALA A 111
LEU A  38
ILE A 107
 None
 1.14A 1bsxB-1ysjA:
undetectable		 1bsxB-1ysjA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 MET A 249
PHE A 182
ALA A 272
ILE A 209
 None
 1.05A 1fxhA-1ysjA:
undetectable
1fxhB-1ysjA:
undetectable		 1fxhA-1ysjA:
19.59
1fxhB-1ysjA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 11 ALA A 136
ALA A 139
VAL A 147
LEU A  51
GLN A  50
 None
 1.23A 1hbpA-1ysjA:
undetectable		 1hbpA-1ysjA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 11 PHE A 129
ILE A 128
ASP A 326
GLY A 138
ALA A 328
 None
 1.29A 1ju6A-1ysjA:
undetectable		 1ju6A-1ysjA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 11 PHE A 129
ILE A 128
ASP A 326
GLY A 138
ALA A 328
 None
 1.29A 1ju6D-1ysjA:
undetectable		 1ju6D-1ysjA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 10 HIS A 350
LEU A  77
PRO A  78
ALA A  97
GLY A  99
 NI  A 382 (-3.4A)
None
None
None
None
 1.36A 1mjqC-1ysjA:
undetectable
1mjqD-1ysjA:
undetectable		 1mjqC-1ysjA:
15.09
1mjqD-1ysjA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 11 HIS A 350
LEU A  77
PRO A  78
ALA A  97
GLY A  99
 NI  A 382 (-3.4A)
None
None
None
None
 1.36A 1mjqI-1ysjA:
undetectable
1mjqJ-1ysjA:
undetectable		 1mjqI-1ysjA:
15.09
1mjqJ-1ysjA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 12 GLY A 323
GLY A 324
LEU A 291
LEU A 175
HIS A 158
 None
None
None
None
NI  A 381 (-3.4A)
 0.95A 1mx1D-1ysjA:
2.6		 1mx1D-1ysjA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 4 ALA A 360
VAL A 363
ALA A 364
HIS A 103
 None
 1.07A 1q23A-1ysjA:
undetectable		 1q23A-1ysjA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 4 ALA A 360
VAL A 363
ALA A 364
HIS A 103
 None
 1.00A 1q23F-1ysjA:
undetectable		 1q23F-1ysjA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 4 ALA A 360
VAL A 363
ALA A 364
HIS A 103
 None
 1.20A 1q23K-1ysjA:
undetectable		 1q23K-1ysjA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 9 ALA A 307
TYR A 367
LEU A 311
GLY A 312
GLY A 166
 None
 1.29A 1ru9H-1ysjA:
1.9
1ru9L-1ysjA:
1.6		 1ru9H-1ysjA:
17.06
1ru9L-1ysjA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUA_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 10 ALA A 307
TYR A 367
LEU A 311
GLY A 312
GLY A 166
 None
 1.28A 1ruaH-1ysjA:
0.0
1ruaL-1ysjA:
0.0		 1ruaH-1ysjA:
17.06
1ruaL-1ysjA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUL_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 9 ALA A 307
TYR A 367
LEU A 311
GLY A 312
GLY A 166
 None
 1.33A 1rulH-1ysjA:
undetectable
1rulL-1ysjA:
undetectable		 1rulH-1ysjA:
17.06
1rulL-1ysjA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.28A 1v54A-1ysjA:
undetectable
1v54C-1ysjA:
undetectable		 1v54A-1ysjA:
19.86
1v54C-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.28A 1v54N-1ysjA:
undetectable
1v54P-1ysjA:
undetectable		 1v54N-1ysjA:
19.86
1v54P-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.28A 1v55A-1ysjA:
undetectable
1v55C-1ysjA:
undetectable		 1v55A-1ysjA:
19.86
1v55C-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA1_1
(CES1 PROTEIN)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 12 GLY A 323
GLY A 324
LEU A 291
LEU A 175
HIS A 158
 None
None
None
None
NI  A 381 (-3.4A)
 0.99A 1ya4A-1ysjA:
undetectable		 1ya4A-1ysjA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 8 GLY A 109
THR A 110
ALA A 111
VAL A  55
 None
 0.80A 2a1hA-1ysjA:
undetectable
2a1hB-1ysjA:
undetectable		 2a1hA-1ysjA:
23.09
2a1hB-1ysjA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 8 VAL A  55
GLY A 109
THR A 110
ALA A 111
 None
 0.80A 2a1hA-1ysjA:
undetectable
2a1hB-1ysjA:
undetectable		 2a1hA-1ysjA:
23.09
2a1hB-1ysjA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_4
(POL POLYPROTEIN)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		3 / 3 ARG A 233
VAL A 229
GLY A 212
 None
 0.62A 2avvE-1ysjA:
undetectable		 2avvE-1ysjA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.28A 2dyrA-1ysjA:
undetectable
2dyrC-1ysjA:
undetectable		 2dyrA-1ysjA:
19.86
2dyrC-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.29A 2dyrN-1ysjA:
undetectable
2dyrP-1ysjA:
undetectable		 2dyrN-1ysjA:
19.86
2dyrP-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.28A 2dysA-1ysjA:
undetectable
2dysC-1ysjA:
undetectable		 2dysA-1ysjA:
19.86
2dysC-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.26A 2dysN-1ysjA:
undetectable
2dysP-1ysjA:
undetectable		 2dysN-1ysjA:
19.86
2dysP-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.28A 2eijA-1ysjA:
undetectable
2eijC-1ysjA:
undetectable		 2eijA-1ysjA:
19.86
2eijC-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.29A 2eijN-1ysjA:
undetectable
2eijP-1ysjA:
undetectable		 2eijN-1ysjA:
19.86
2eijP-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.30A 2eikA-1ysjA:
undetectable
2eikC-1ysjA:
undetectable		 2eikA-1ysjA:
19.86
2eikC-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.31A 2eikN-1ysjA:
undetectable
2eikP-1ysjA:
undetectable		 2eikN-1ysjA:
19.86
2eikP-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.28A 2eilA-1ysjA:
undetectable
2eilC-1ysjA:
undetectable		 2eilA-1ysjA:
19.86
2eilC-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.30A 2eilN-1ysjA:
undetectable
2eilP-1ysjA:
undetectable		 2eilN-1ysjA:
19.86
2eilP-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.29A 2eimA-1ysjA:
undetectable
2eimC-1ysjA:
undetectable		 2eimA-1ysjA:
19.86
2eimC-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.34A 2eimN-1ysjA:
undetectable
2eimP-1ysjA:
0.2		 2eimN-1ysjA:
19.86
2eimP-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.26A 2einA-1ysjA:
1.1
2einC-1ysjA:
undetectable		 2einA-1ysjA:
19.86
2einC-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.30A 2einN-1ysjA:
undetectable
2einP-1ysjA:
0.0		 2einN-1ysjA:
19.86
2einP-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 MET A 157
ARG A  14
LEU A 361
VAL A 165
 None
 1.37A 2hrcA-1ysjA:
3.1		 2hrcA-1ysjA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.27A 2y69A-1ysjA:
undetectable
2y69C-1ysjA:
undetectable		 2y69A-1ysjA:
19.86
2y69C-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_A_SAMA298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 12 ALA A  57
PHE A 129
GLY A  54
THR A  53
VAL A 142
 None
 1.22A 2zifA-1ysjA:
undetectable		 2zifA-1ysjA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.27A 2zxwA-1ysjA:
undetectable
2zxwC-1ysjA:
undetectable		 2zxwA-1ysjA:
19.86
2zxwC-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.28A 2zxwN-1ysjA:
undetectable
2zxwP-1ysjA:
undetectable		 2zxwN-1ysjA:
19.86
2zxwP-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.27A 3abkA-1ysjA:
undetectable
3abkC-1ysjA:
undetectable		 3abkA-1ysjA:
19.86
3abkC-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.29A 3abkN-1ysjA:
undetectable
3abkP-1ysjA:
undetectable		 3abkN-1ysjA:
19.86
3abkP-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.27A 3abmN-1ysjA:
undetectable
3abmP-1ysjA:
undetectable		 3abmN-1ysjA:
19.86
3abmP-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.33A 3ag1A-1ysjA:
undetectable
3ag1C-1ysjA:
undetectable		 3ag1A-1ysjA:
19.86
3ag1C-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.30A 3ag1N-1ysjA:
undetectable
3ag1P-1ysjA:
undetectable		 3ag1N-1ysjA:
19.86
3ag1P-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.29A 3ag2A-1ysjA:
undetectable
3ag2C-1ysjA:
undetectable		 3ag2A-1ysjA:
19.86
3ag2C-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.28A 3ag2N-1ysjA:
undetectable
3ag2P-1ysjA:
undetectable		 3ag2N-1ysjA:
19.86
3ag2P-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.30A 3ag3A-1ysjA:
undetectable
3ag3C-1ysjA:
undetectable		 3ag3A-1ysjA:
19.86
3ag3C-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.28A 3ag3N-1ysjA:
undetectable
3ag3P-1ysjA:
undetectable		 3ag3N-1ysjA:
19.86
3ag3P-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.29A 3ag4A-1ysjA:
0.4
3ag4C-1ysjA:
undetectable		 3ag4A-1ysjA:
19.86
3ag4C-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.30A 3ag4N-1ysjA:
undetectable
3ag4P-1ysjA:
undetectable		 3ag4N-1ysjA:
19.86
3ag4P-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.29A 3asnA-1ysjA:
undetectable
3asnC-1ysjA:
undetectable		 3asnA-1ysjA:
19.86
3asnC-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 12 MET A 341
PHE A 368
ALA A 308
ALA A 364
GLY A 156
 None
 0.97A 3c6gB-1ysjA:
undetectable		 3c6gB-1ysjA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		3 / 3 GLU A 134
GLU A 133
TRP A 349
 NI  A 382 ( 2.1A)
NI  A 381 (-4.0A)
None
 1.34A 3hrdA-1ysjA:
undetectable
3hrdE-1ysjA:
undetectable
3hrdF-1ysjA:
undetectable		 3hrdA-1ysjA:
24.35
3hrdE-1ysjA:
24.35
3hrdF-1ysjA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 9 ILE A  45
ILE A  43
VAL A  55
ILE A 108
ILE A  34
 None
 1.24A 3p4wB-1ysjA:
undetectable		 3p4wB-1ysjA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 12 GLY A 345
LEU A 163
MET A 341
GLU A 358
ALA A 360
 None
 1.02A 3sxjA-1ysjA:
undetectable		 3sxjA-1ysjA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 12 GLY A 345
LEU A 163
MET A 341
GLU A 358
ALA A 360
 None
 1.02A 3sxjB-1ysjA:
undetectable		 3sxjB-1ysjA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 12 ILE A 108
VAL A  67
ILE A  74
VAL A 147
VAL A 151
 None
 0.93A 3w68C-1ysjA:
undetectable		 3w68C-1ysjA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 8 GLY A 169
GLY A 342
VAL A 363
TYR A 367
 None
 0.79A 4fgzA-1ysjA:
undetectable		 4fgzA-1ysjA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PQA_A_X8ZA401_1
(SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 11 HIS A 100
GLU A 133
GLU A 134
GLY A 323
HIS A 350
 NI  A 381 (-3.2A)
NI  A 381 (-4.0A)
NI  A 382 ( 2.1A)
None
NI  A 382 (-3.4A)
 0.78A 4pqaA-1ysjA:
28.1		 4pqaA-1ysjA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_B_STRB601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 9 VAL A 363
GLY A 312
ALA A 309
THR A 315
ILE A 374
 None
 0.99A 4r21B-1ysjA:
undetectable		 4r21B-1ysjA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 4 PHE A  25
ASP A  75
GLY A 138
SER A  24
 None
 1.39A 4xp9C-1ysjA:
undetectable		 4xp9C-1ysjA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.27A 5b1aN-1ysjA:
undetectable
5b1aP-1ysjA:
undetectable		 5b1aN-1ysjA:
19.86
5b1aP-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.28A 5b1bN-1ysjA:
undetectable
5b1bP-1ysjA:
undetectable		 5b1bN-1ysjA:
19.86
5b1bP-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.30A 5b3sN-1ysjA:
undetectable
5b3sP-1ysjA:
undetectable		 5b3sN-1ysjA:
19.86
5b3sP-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 5 PHE A 300
ILE A  68
GLY A 336
ILE A 379
 None
 0.55A 5dzkB-1ysjA:
undetectable
5dzkI-1ysjA:
undetectable
5dzkW-1ysjA:
undetectable		 5dzkB-1ysjA:
20.79
5dzkI-1ysjA:
21.99
5dzkW-1ysjA:
1.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 5 PHE A 300
ILE A  68
GLY A 336
ILE A 379
 None
 0.58A 5dzkd-1ysjA:
undetectable
5dzkk-1ysjA:
undetectable
5dzky-1ysjA:
undetectable		 5dzkd-1ysjA:
20.79
5dzkk-1ysjA:
21.99
5dzky-1ysjA:
1.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.25A 5iy5A-1ysjA:
undetectable
5iy5C-1ysjA:
undetectable		 5iy5A-1ysjA:
19.86
5iy5C-1ysjA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		6 / 12 ARG A 269
ILE A 184
ALA A 276
GLY A 278
ALA A 281
ILE A 186
 None
 1.45A 5kb6B-1ysjA:
undetectable		 5kb6B-1ysjA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 12 PHE A 127
ALA A 111
SER A 365
GLY A  61
ILE A  43
 None
 1.12A 5m24A-1ysjA:
undetectable		 5m24A-1ysjA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 10 VAL A 375
THR A 378
ILE A 379
GLY A 298
PHE A 300
 None
 1.15A 5mxbA-1ysjA:
undetectable		 5mxbA-1ysjA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.29A 5x19N-1ysjA:
undetectable
5x19P-1ysjA:
undetectable		 5x19N-1ysjA:
19.86
5x19P-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.28A 5x1bN-1ysjA:
undetectable
5x1bP-1ysjA:
undetectable		 5x1bN-1ysjA:
19.86
5x1bP-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.30A 5x1fN-1ysjA:
undetectable
5x1fP-1ysjA:
undetectable		 5x1fN-1ysjA:
19.86
5x1fP-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 12 ILE A 209
GLY A 212
VAL A 234
ILE A 231
MET A 249
 None
 1.00A 5ycnA-1ysjA:
undetectable		 5ycnA-1ysjA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.28A 5zcqN-1ysjA:
undetectable
5zcqP-1ysjA:
undetectable		 5zcqN-1ysjA:
19.86
5zcqP-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 4 HIS A 158
CYH A  98
HIS A 100
HIS A 103
 NI  A 381 (-3.4A)
NI  A 381 ( 2.5A)
NI  A 381 (-3.2A)
None
 1.42A 5zrdA-1ysjA:
undetectable		 5zrdA-1ysjA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 12 PHE A  25
HIS A  96
LYS A  52
VAL A 142
ASP A 326
 None
 1.38A 6bxnA-1ysjA:
1.0		 6bxnA-1ysjA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		5 / 12 PHE A  25
HIS A  96
LYS A  52
VAL A 142
ASP A 326
 None
 1.34A 6bxnB-1ysjA:
undetectable		 6bxnB-1ysjA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.27A 6nknA-1ysjA:
undetectable
6nknC-1ysjA:
undetectable		 6nknA-1ysjA:
19.86
6nknC-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.31A 6nmfN-1ysjA:
undetectable
6nmfP-1ysjA:
undetectable		 6nmfN-1ysjA:
19.86
6nmfP-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.28A 6nmpA-1ysjA:
undetectable
6nmpC-1ysjA:
0.2		 6nmpA-1ysjA:
19.86
6nmpC-1ysjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ysj PROTEIN YXEP
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 357
THR A 343
HIS A 100
 NI  A 381 (-3.4A)
None
None
NI  A 381 (-3.2A)
 1.29A 6nmpN-1ysjA:
undetectable
6nmpP-1ysjA:
undetectable		 6nmpN-1ysjA:
19.86
6nmpP-1ysjA:
22.20