SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ytm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 7 PHE A 173
PHE A  66
VAL A  68
VAL A 185
 None
 0.85A 1epbA-1ytmA:
undetectable		 1epbA-1ytmA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA154_1
(CALMODULIN)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 7 GLU A 105
LEU A 106
GLU A 133
GLU A  40
 None
 1.14A 1linA-1ytmA:
undetectable		 1linA-1ytmA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 8 SER A 379
ASN A 514
GLN A 512
PHE A 511
 None
 1.29A 1p6kA-1ytmA:
undetectable		 1p6kA-1ytmA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 8 SER A 379
ASN A 514
GLN A 512
PHE A 511
 None
 1.27A 1p6kB-1ytmA:
undetectable		 1p6kB-1ytmA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 8 SER A 379
ASN A 514
GLN A 512
PHE A 511
 None
 1.26A 1rs6A-1ytmA:
undetectable		 1rs6A-1ytmA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 8 SER A 379
ASN A 514
GLN A 512
PHE A 511
 None
 1.21A 1rs6B-1ytmA:
undetectable		 1rs6B-1ytmA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 8 SER A 379
ASN A 514
GLN A 512
PHE A 511
 None
 1.16A 1rs7B-1ytmA:
undetectable		 1rs7B-1ytmA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 4 LEU A 419
LEU A 378
SER A 401
LEU A 408
 None
 1.06A 1ya3A-1ytmA:
undetectable		 1ya3A-1ytmA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 8 SER A 379
ASN A 514
GLN A 512
PHE A 511
 None
 1.28A 1zzqA-1ytmA:
undetectable		 1zzqA-1ytmA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 8 SER A 379
ASN A 514
GLN A 512
PHE A 511
 None
 1.27A 1zzqB-1ytmA:
undetectable		 1zzqB-1ytmA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 8 SER A 379
ASN A 514
GLN A 512
PHE A 511
 None
 1.28A 1zzuB-1ytmA:
undetectable		 1zzuB-1ytmA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 11 ILE A 195
PHE A 186
ARG A  60
GLY A 207
LYS A 206
 None
None
OXD  A 543 (-4.1A)
None
MN  A 999 ( 2.4A)
 1.29A 2bxmA-1ytmA:
undetectable		 2bxmA-1ytmA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 8 ARG A  60
THR A 198
GLY A 202
ILE A 195
 OXD  A 543 (-4.1A)
None
None
None
 0.78A 2f9wA-1ytmA:
undetectable
2f9wB-1ytmA:
undetectable		 2f9wA-1ytmA:
20.85
2f9wB-1ytmA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 5 PHE A 472
PHE A 511
PHE A 399
VAL A 361
 None
 1.14A 2lh6A-1ytmA:
0.0		 2lh6A-1ytmA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA501_1
(CYTOCHROME P450 2C8)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 11 GLY A 247
SER A 252
SER A 227
ALA A 348
ILE A 456
 ATP  A 541 (-3.1A)
None
None
None
None
 0.95A 2nnhA-1ytmA:
undetectable		 2nnhA-1ytmA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 5 GLY A 202
GLY A 201
PHE A 145
PHE A 130
 None
 1.03A 2qr2A-1ytmA:
undetectable
2qr2B-1ytmA:
undetectable		 2qr2A-1ytmA:
21.15
2qr2B-1ytmA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		7 / 8 ARG A  60
LYS A 205
LYS A 206
HIS A 225
SER A 244
ASP A 263
ARG A 327
 OXD  A 543 (-4.1A)
OXD  A 543 ( 4.2A)
MN  A 999 ( 2.4A)
MN  A 999 (-3.4A)
OXD  A 543 ( 2.3A)
MN  A 999 (-2.5A)
ATP  A 541 ( 2.8A)
 0.70A 2rk8A-1ytmA:
30.7		 2rk8A-1ytmA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_B_PPFB3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		7 / 7 ARG A  60
LYS A 205
LYS A 206
HIS A 225
SER A 244
ASP A 263
ARG A 327
 OXD  A 543 (-4.1A)
OXD  A 543 ( 4.2A)
MN  A 999 ( 2.4A)
MN  A 999 (-3.4A)
OXD  A 543 ( 2.3A)
MN  A 999 (-2.5A)
ATP  A 541 ( 2.8A)
 0.73A 2rk8B-1ytmA:
29.2		 2rk8B-1ytmA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A600_1
(ORF12)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 11 THR A 398
ALA A 406
GLY A 404
PHE A 407
ARG A  60
 None
None
None
OXD  A 543 (-4.6A)
OXD  A 543 (-4.1A)
 1.20A 2xf3A-1ytmA:
0.0		 2xf3A-1ytmA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B600_1
(ORF12)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 11 THR A 398
ALA A 406
GLY A 404
PHE A 407
ARG A  60
 None
None
None
OXD  A 543 (-4.6A)
OXD  A 543 (-4.1A)
 1.18A 2xf3B-1ytmA:
0.0		 2xf3B-1ytmA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1437_1
(ORF12)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 11 THR A 398
ALA A 406
GLY A 404
PHE A 407
ARG A  60
 None
None
None
OXD  A 543 (-4.6A)
OXD  A 543 (-4.1A)
 1.20A 2xh9A-1ytmA:
undetectable		 2xh9A-1ytmA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 8 ILE A 452
ASN A 434
SER A 355
SER A 366
 None
 1.04A 2zw9B-1ytmA:
undetectable		 2zw9B-1ytmA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 12 MET A 423
ALA A 428
VAL A 351
PHE A 241
LEU A 378
 None
 1.27A 3b0wA-1ytmA:
0.0		 3b0wA-1ytmA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 12 MET A 423
ALA A 428
VAL A 351
PHE A 241
LEU A 378
 None
 1.29A 3b0wB-1ytmA:
undetectable		 3b0wB-1ytmA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 11 PHE A 186
ASP A  86
ILE A 195
GLU A 203
ASP A  64
 None
 1.33A 3ko0A-1ytmA:
undetectable
3ko0B-1ytmA:
undetectable
3ko0C-1ytmA:
undetectable
3ko0D-1ytmA:
undetectable		 3ko0A-1ytmA:
11.22
3ko0B-1ytmA:
11.22
3ko0C-1ytmA:
11.22
3ko0D-1ytmA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 11 GLU A 203
ASP A  64
ILE A 195
PHE A 186
ASP A  86
 None
 1.40A 3ko0E-1ytmA:
undetectable
3ko0F-1ytmA:
undetectable
3ko0G-1ytmA:
undetectable
3ko0H-1ytmA:
undetectable		 3ko0E-1ytmA:
11.22
3ko0F-1ytmA:
11.22
3ko0G-1ytmA:
11.22
3ko0H-1ytmA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR202_1
(PROTEIN S100-A4)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 11 GLU A 203
ASP A  64
ILE A 195
ASP A  86
PHE A 186
 None
 1.34A 3ko0Q-1ytmA:
0.0
3ko0R-1ytmA:
undetectable
3ko0S-1ytmA:
undetectable
3ko0T-1ytmA:
undetectable		 3ko0Q-1ytmA:
11.22
3ko0R-1ytmA:
11.22
3ko0S-1ytmA:
11.22
3ko0T-1ytmA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT202_1
(PROTEIN S100-A4)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 11 ASP A  86
PHE A 186
GLU A 203
ASP A  64
ILE A 195
 None
 1.36A 3ko0Q-1ytmA:
0.0
3ko0R-1ytmA:
undetectable
3ko0S-1ytmA:
undetectable
3ko0T-1ytmA:
undetectable		 3ko0Q-1ytmA:
11.22
3ko0R-1ytmA:
11.22
3ko0S-1ytmA:
11.22
3ko0T-1ytmA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 11 PRO A 158
ASP A 115
LEU A 116
VAL A 141
ALA A 138
 None
 1.33A 3n23C-1ytmA:
undetectable		 3n23C-1ytmA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 8 SER A 379
ASN A 514
GLN A 512
PHE A 511
 None
 1.25A 3n62B-1ytmA:
undetectable		 3n62B-1ytmA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 11 ALA A 425
ILE A 221
GLY A 271
ALA A 347
VAL A 351
 None
 1.08A 3rukD-1ytmA:
undetectable		 3rukD-1ytmA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 8 GLY A 207
SER A 210
MET A 208
ILE A  67
LEU A 188
 None
 1.22A 3v1nA-1ytmA:
undetectable		 3v1nA-1ytmA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 12 LYS A 206
GLY A 242
GLY A 404
LEU A 251
ASP A 263
 MN  A 999 ( 2.4A)
None
None
ATP  A 541 ( 4.5A)
MN  A 999 (-2.5A)
 1.13A 4blvB-1ytmA:
undetectable		 4blvB-1ytmA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA505_0
(RNA POLYMERASE
3D-POL)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		3 / 3 CYH A 118
ASN A 274
LYS A 205
 None
None
OXD  A 543 ( 4.2A)
 0.95A 4k50A-1ytmA:
undetectable		 4k50A-1ytmA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 7 SER A 379
ASN A 514
GLN A 512
PHE A 511
 None
 1.36A 4kcnB-1ytmA:
undetectable		 4kcnB-1ytmA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 8 VAL A 170
LEU A 176
LEU A 178
ILE A 194
 None
 0.86A 4lzrA-1ytmA:
undetectable		 4lzrA-1ytmA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		3 / 3 PRO A 148
ASN A  21
HIS A  20
 None
 1.01A 4ma3H-1ytmA:
0.0
4ma3L-1ytmA:
undetectable		 4ma3H-1ytmA:
17.63
4ma3L-1ytmA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 12 LEU A 251
ARG A 450
GLY A 451
VAL A 433
VAL A 365
 ATP  A 541 ( 4.5A)
None
None
None
None
 0.97A 4nkvA-1ytmA:
undetectable		 4nkvA-1ytmA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		3 / 3 PHE A 511
THR A 246
LEU A 432
 None
ATP  A 541 (-4.8A)
None
 0.72A 4qztA-1ytmA:
undetectable		 4qztA-1ytmA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 12 GLY A  55
PHE A 145
ILE A 128
GLY A 207
THR A  58
 None
 1.13A 4zdyA-1ytmA:
undetectable		 4zdyA-1ytmA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 5 VAL A 502
ILE A 456
PRO A 490
THR A 466
 None
 0.98A 4ze1A-1ytmA:
undetectable		 4ze1A-1ytmA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G44_A_YTZA1512_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 9 LEU A 101
LEU A 196
ALA A  94
VAL A  90
ALA A 183
 None
 1.30A 5g44A-1ytmA:
undetectable		 5g44A-1ytmA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		4 / 4 ASN A 236
ILE A 452
TYR A 431
PHE A 241
 None
 1.29A 5igvA-1ytmA:
0.0		 5igvA-1ytmA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA510_1
(PROTON-GATED ION
CHANNEL)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 9 ILE A 452
ALA A 455
ILE A 456
ILE A 367
PRO A 477
 None
 0.90A 5mvmA-1ytmA:
undetectable
5mvmE-1ytmA:
undetectable		 5mvmA-1ytmA:
10.71
5mvmE-1ytmA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 8 ILE A 367
PRO A 477
ILE A 452
ALA A 455
ILE A 456
 None
 0.86A 5mvmA-1ytmA:
undetectable
5mvmB-1ytmA:
undetectable		 5mvmA-1ytmA:
10.71
5mvmB-1ytmA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]
(Anaerobiospirill
um
succiniciproduce
ns) 		5 / 10 ILE A 367
PRO A 477
ILE A 452
ALA A 455
ILE A 456
 None
 0.89A 5mvmD-1ytmA:
undetectable
5mvmE-1ytmA:
undetectable		 5mvmD-1ytmA:
10.71
5mvmE-1ytmA:
10.71