SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yul'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 4 THR A  85
LEU A  89
VAL A  92
LEU A  96
 None
 0.52A 1fbmD-1yulA:
undetectable		 1fbmD-1yulA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 5 THR A  85
LEU A  89
VAL A  92
LEU A  96
 None
 0.48A 1fbmE-1yulA:
undetectable		 1fbmE-1yulA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		3 / 4 VAL A 131
TRP A 171
TRP A 108
 None
 0.97A 1gmkA-1yulA:
undetectable
1gmkB-1yulA:
undetectable		 1gmkA-1yulA:
7.25
1gmkB-1yulA:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 4 THR A  85
LEU A  89
VAL A  92
LEU A  96
 None
 0.85A 1mz9D-1yulA:
undetectable		 1mz9D-1yulA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		3 / 3 THR A  85
LEU A  89
VAL A  92
 None
 0.35A 1mz9E-1yulA:
undetectable		 1mz9E-1yulA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  37
ILE A   5
GLY A   6
GLY A   9
ALA A  27
 None
 1.01A 1vptA-1yulA:
2.4		 1vptA-1yulA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_2
(PROTEASE)		 1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 8 LEU A  38
ILE A 106
ILE A  86
LEU A   7
 None
 0.76A 2o4nB-1yulA:
undetectable		 2o4nB-1yulA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 5 LEU A  70
LEU A  37
LEU A  57
MET A  20
 None
 1.13A 2oaxF-1yulA:
undetectable		 2oaxF-1yulA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 9 GLN A  55
VAL A  51
ILE A 182
VAL A 196
VAL A 200
 None
 1.45A 3fi0C-1yulA:
4.2		 3fi0C-1yulA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 9 GLN A  55
VAL A  51
ILE A 182
VAL A 196
VAL A 200
 None
 1.45A 3fi0F-1yulA:
undetectable		 3fi0F-1yulA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 9 GLN A  55
VAL A  51
ILE A 182
VAL A 196
VAL A 200
 None
 1.47A 3fi0H-1yulA:
4.0		 3fi0H-1yulA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 9 GLN A  55
VAL A  51
ILE A 182
VAL A 196
VAL A 200
 None
 1.50A 3fi0L-1yulA:
undetectable		 3fi0L-1yulA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 9 GLN A  55
VAL A  51
ILE A 182
VAL A 196
VAL A 200
 None
 1.41A 3fi0N-1yulA:
3.9		 3fi0N-1yulA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 8 LEU A 105
VAL A 130
ALA A  27
LEU A  32
 None
 0.76A 4qrcA-1yulA:
undetectable		 4qrcA-1yulA:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  92
LEU A  96
LEU A  32
GLY A   6
LEU A  38
 None
 1.07A 4rrwC-1yulA:
undetectable		 4rrwC-1yulA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  92
LEU A  96
LEU A  32
GLY A   6
LEU A  38
 None
 1.07A 4rrzC-1yulA:
undetectable		 4rrzC-1yulA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 5 GLY A  10
THR A  11
HIS A  19
SER A 178
 None
None
CIT  A 230 (-3.8A)
CIT  A 230 (-3.3A)
 0.51A 6jmjA-1yulA:
14.4		 6jmjA-1yulA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 7 GLY A  10
THR A  11
PHE A  12
HIS A  19
SER A 178
 None
None
None
CIT  A 230 (-3.8A)
CIT  A 230 (-3.3A)
 0.54A 6jnhA-1yulA:
14.4		 6jnhA-1yulA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 6 GLY A  10
THR A  11
HIS A  19
SER A 178
 None
None
CIT  A 230 (-3.8A)
CIT  A 230 (-3.3A)
 0.54A 6jogA-1yulA:
14.4		 6jogA-1yulA:
23.89