SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yv9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_B_CAMB502_0
(CYTOCHROME P450-CAM)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
4 / 5 TYR A  17
VAL A  54
VAL A  43
ASP A  11
None
None
None
PO4  A3001 (-3.0A)
1.45A 1dz6B-1yv9A:
undetectable
1dz6B-1yv9A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
4 / 6 ASP A 208
ASN A 209
ASP A  11
TYR A  17
None
None
PO4  A3001 (-3.0A)
None
1.11A 1hpkA-1yv9A:
undetectable
1hpkA-1yv9A:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 11 MET A 205
THR A 212
GLY A 182
ASN A  45
ILE A 181
None
PO4  A3001 ( 4.5A)
None
PO4  A3001 (-4.3A)
None
1.41A 1odiB-1yv9A:
undetectable
1odiB-1yv9A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 11 MET A 205
THR A 212
GLY A 182
ASN A  45
ILE A 181
None
PO4  A3001 ( 4.5A)
None
PO4  A3001 (-4.3A)
None
1.46A 1odiC-1yv9A:
undetectable
1odiC-1yv9A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 11 MET A 205
THR A 212
GLY A 182
ASN A  45
ILE A 181
None
PO4  A3001 ( 4.5A)
None
PO4  A3001 (-4.3A)
None
1.40A 1odiE-1yv9A:
undetectable
1odiE-1yv9A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
4 / 8 THR A 174
LEU A 143
VAL A 167
VAL A 170
None
0.91A 1t86A-1yv9A:
undetectable
1t86A-1yv9A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_B_SAMB301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 12 THR A 242
ILE A 222
GLY A 221
ILE A 218
GLU A 199
None
0.98A 1vq1B-1yv9A:
undetectable
1vq1B-1yv9A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
4 / 7 VAL A 248
LEU A  33
SER A 229
ASP A 208
None
1.04A 2hdnF-1yv9A:
undetectable
2hdnG-1yv9A:
undetectable
2hdnH-1yv9A:
undetectable
2hdnF-1yv9A:
22.71
2hdnG-1yv9A:
15.97
2hdnH-1yv9A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
4 / 8 ILE A 204
PHE A  29
GLY A 207
ILE A 214
None
0.94A 2qwxA-1yv9A:
3.5
2qwxB-1yv9A:
3.3
2qwxA-1yv9A:
21.99
2qwxB-1yv9A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_2
(PHOSPHOLIPASE A2)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 9 VAL A 120
VAL A 119
GLY A 146
PRO A 178
THR A 176
None
1.48A 3bjwG-1yv9A:
undetectable
3bjwG-1yv9A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
4 / 7 VAL A 131
ILE A 138
GLN A 139
GLY A 141
None
0.82A 3bjwB-1yv9A:
undetectable
3bjwB-1yv9A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_1
(PHOSPHOLIPASE A2)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 10 VAL A 120
VAL A 119
GLY A 146
PRO A 178
THR A 176
None
1.50A 3bjwD-1yv9A:
0.0
3bjwD-1yv9A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
4 / 7 VAL A 131
ILE A 138
GLN A 139
GLY A 141
None
0.78A 3bjwF-1yv9A:
undetectable
3bjwF-1yv9A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_1
(HIV-1 PROTEASE)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 12 LEU A 104
GLY A  98
GLY A 121
ILE A  94
ILE A 103
None
1.04A 3d20A-1yv9A:
undetectable
3d20A-1yv9A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
4 / 4 ILE A 204
GLN A   6
ILE A  10
LEU A   3
None
1.15A 3dzyD-1yv9A:
undetectable
3dzyD-1yv9A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 8 LEU A 104
GLY A  98
GLY A 121
ILE A  94
ILE A 103
None
1.17A 3ekpA-1yv9A:
undetectable
3ekpA-1yv9A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 8 GLY A 141
ALA A 142
ASP A 116
LEU A 136
VAL A 120
None
1.18A 3em6A-1yv9A:
undetectable
3em6A-1yv9A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
6 / 12 LEU A 104
GLY A  98
GLY A 121
ILE A  94
VAL A  91
ILE A 103
None
1.27A 3lzuB-1yv9A:
undetectable
3lzuB-1yv9A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 11 ILE A 103
VAL A 119
PHE A  92
VAL A  91
ILE A  94
None
1.11A 3rf4A-1yv9A:
undetectable
3rf4C-1yv9A:
undetectable
3rf4A-1yv9A:
22.46
3rf4C-1yv9A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 11 ILE A  94
ILE A 103
VAL A 119
PHE A  92
VAL A  91
None
1.14A 3rf4A-1yv9A:
undetectable
3rf4B-1yv9A:
undetectable
3rf4A-1yv9A:
22.46
3rf4B-1yv9A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 11 ILE A  94
ILE A 103
VAL A 119
PHE A  92
VAL A  91
None
1.11A 3rf4B-1yv9A:
undetectable
3rf4C-1yv9A:
undetectable
3rf4B-1yv9A:
22.46
3rf4C-1yv9A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
6 / 12 LEU A 104
GLY A  98
GLY A 121
ILE A  94
VAL A  91
ILE A 103
None
1.24A 3tkwB-1yv9A:
undetectable
3tkwB-1yv9A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_B_QMRB1214_1
(CAPITELLA TELETA
ACHBP)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 9 ILE A 222
PHE A  29
PHE A 256
VAL A 203
TYR A   5
None
1.24A 4afgA-1yv9A:
0.0
4afgE-1yv9A:
0.0
4afgA-1yv9A:
22.26
4afgE-1yv9A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 12 ILE A 153
THR A 147
LEU A  99
GLY A  95
VAL A 166
None
1.06A 4c9oB-1yv9A:
undetectable
4c9oB-1yv9A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
4 / 7 THR A 174
LEU A 143
VAL A 167
VAL A 170
None
0.89A 4cp4A-1yv9A:
undetectable
4cp4A-1yv9A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 12 ASN A 152
ILE A 153
ASN A 148
LEU A 159
THR A  44
None
None
None
None
PO4  A3001 (-4.2A)
1.07A 4e3aA-1yv9A:
undetectable
4e3aA-1yv9A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 12 ASN A 152
ILE A 153
ASN A 148
LEU A 159
THR A  44
None
None
None
None
PO4  A3001 (-4.2A)
1.07A 4jkuB-1yv9A:
undetectable
4jkuB-1yv9A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 12 ASN A 152
ILE A 153
ASN A 148
LEU A 159
THR A  44
None
None
None
None
PO4  A3001 (-4.2A)
1.08A 4k8pA-1yv9A:
undetectable
4k8pA-1yv9A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 12 ASN A 152
ILE A 153
ASN A 148
LEU A 159
THR A  44
None
None
None
None
PO4  A3001 (-4.2A)
1.07A 4k8pB-1yv9A:
undetectable
4k8pB-1yv9A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 12 ASN A 152
ILE A 153
ASN A 148
LEU A 159
THR A  44
None
None
None
None
PO4  A3001 (-4.2A)
1.09A 4k8tA-1yv9A:
undetectable
4k8tA-1yv9A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 12 ASN A 152
ILE A 153
ASN A 148
LEU A 159
THR A  44
None
None
None
None
PO4  A3001 (-4.2A)
1.07A 4k8tB-1yv9A:
undetectable
4k8tB-1yv9A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 12 ASN A 152
ILE A 153
ASN A 148
LEU A 159
THR A  44
None
None
None
None
PO4  A3001 (-4.2A)
1.07A 4k93A-1yv9A:
undetectable
4k93A-1yv9A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 12 ASN A 152
ILE A 153
ASN A 148
LEU A 159
THR A  44
None
None
None
None
PO4  A3001 (-4.2A)
1.08A 4k93B-1yv9A:
undetectable
4k93B-1yv9A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 12 ASN A 152
ILE A 153
ASN A 148
LEU A 159
THR A  44
None
None
None
None
PO4  A3001 (-4.2A)
1.08A 4k9iA-1yv9A:
undetectable
4k9iA-1yv9A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 12 ASN A 152
ILE A 153
ASN A 148
LEU A 159
THR A  44
None
None
None
None
PO4  A3001 (-4.2A)
1.07A 4k9iB-1yv9A:
undetectable
4k9iB-1yv9A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 12 ASN A 152
ILE A 153
ASN A 148
LEU A 159
THR A  44
None
None
None
None
PO4  A3001 (-4.2A)
1.08A 4lbxA-1yv9A:
undetectable
4lbxA-1yv9A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 12 ASN A 152
ILE A 153
ASN A 148
LEU A 159
THR A  44
None
None
None
None
PO4  A3001 (-4.2A)
1.08A 4lbxB-1yv9A:
undetectable
4lbxB-1yv9A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 12 ASN A 152
ILE A 153
ASN A 148
LEU A 159
THR A  44
None
None
None
None
PO4  A3001 (-4.2A)
1.08A 4lc4A-1yv9A:
undetectable
4lc4A-1yv9A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
5 / 12 ASN A 152
ILE A 153
ASN A 148
LEU A 159
THR A  44
None
None
None
None
PO4  A3001 (-4.2A)
1.09A 4lc4B-1yv9A:
undetectable
4lc4B-1yv9A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
4 / 8 ILE A 204
PHE A  29
GLY A 207
ILE A 214
None
0.92A 4qogA-1yv9A:
undetectable
4qogB-1yv9A:
3.4
4qogA-1yv9A:
21.99
4qogB-1yv9A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1103_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
4 / 8 THR A 176
PRO A 178
TYR A 180
GLY A 121
None
0.90A 5nzyA-1yv9A:
3.1
5nzyA-1yv9A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
4 / 6 ILE A 214
ILE A  23
LEU A 251
PHE A  62
None
0.98A 5vkqB-1yv9A:
undetectable
5vkqC-1yv9A:
undetectable
5vkqB-1yv9A:
9.70
5vkqC-1yv9A:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
4 / 6 ILE A 214
ILE A  23
LEU A 251
PHE A  62
None
0.99A 5vkqC-1yv9A:
undetectable
5vkqD-1yv9A:
undetectable
5vkqC-1yv9A:
9.70
5vkqD-1yv9A:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)
1yv9 HYDROLASE, HALOACID
DEHALOGENASE FAMILY

(Enterococcus
faecalis)
4 / 4 ASP A 208
ILE A  23
PRO A  22
LEU A  18
None
1.45A 6mkeB-1yv9A:
undetectable
6mkeB-1yv9A:
16.59