SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yvd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1yvd RAS-RELATED PROTEIN
RAB-22A
(Mus
musculus) 		3 / 3 GLU A 127
GLU A 146
LEU A  96
 None
 0.73A 1v8bA-1yvdA:
2.9		 1v8bA-1yvdA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1yvd RAS-RELATED PROTEIN
RAB-22A
(Mus
musculus) 		3 / 3 GLU A 127
GLU A 146
LEU A  96
 None
 0.73A 1v8bB-1yvdA:
2.9		 1v8bB-1yvdA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 1yvd RAS-RELATED PROTEIN
RAB-22A
(Mus
musculus) 		5 / 12 THR A  37
GLY A  17
GLY A  15
GLY A  63
ASP A 121
 MG  A 850 ( 3.2A)
GNP  A 900 (-3.2A)
GNP  A 900 (-3.8A)
GNP  A 900 (-3.2A)
GNP  A 900 (-3.0A)
 1.04A 2b25A-1yvdA:
2.5		 2b25A-1yvdA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 1yvd RAS-RELATED PROTEIN
RAB-22A
(Mus
musculus) 		5 / 12 ALA A  69
LEU A  70
ALA A  71
THR A  61
ILE A  38
 None
 1.21A 2jjpA-1yvdA:
undetectable		 2jjpA-1yvdA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1yvd RAS-RELATED PROTEIN
RAB-22A
(Mus
musculus) 		5 / 12 ILE A  87
GLU A 130
PHE A 144
ALA A  80
LEU A  10
 None
 1.00A 2xkwB-1yvdA:
undetectable		 2xkwB-1yvdA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 1yvd RAS-RELATED PROTEIN
RAB-22A
(Mus
musculus) 		4 / 5 TYR A 136
THR A  95
PHE A  93
ILE A  83
 None
 1.22A 4jx1E-1yvdA:
undetectable		 4jx1E-1yvdA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1yvd RAS-RELATED PROTEIN
RAB-22A
(Mus
musculus) 		4 / 5 GLU A 127
THR A  88
GLU A 146
LEU A  96
 None
 1.17A 5hm8A-1yvdA:
2.9		 5hm8A-1yvdA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1yvd RAS-RELATED PROTEIN
RAB-22A
(Mus
musculus) 		4 / 5 GLU A 127
THR A  88
GLU A 146
LEU A  96
 None
 1.17A 5hm8B-1yvdA:
4.8		 5hm8B-1yvdA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1yvd RAS-RELATED PROTEIN
RAB-22A
(Mus
musculus) 		4 / 5 GLU A 127
THR A  88
GLU A 146
LEU A  96
 None
 1.17A 5hm8C-1yvdA:
2.9		 5hm8C-1yvdA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1yvd RAS-RELATED PROTEIN
RAB-22A
(Mus
musculus) 		4 / 5 GLU A 127
THR A  88
GLU A 146
LEU A  96
 None
 1.17A 5hm8D-1yvdA:
4.9		 5hm8D-1yvdA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1yvd RAS-RELATED PROTEIN
RAB-22A
(Mus
musculus) 		4 / 5 GLU A 127
THR A  88
GLU A 146
LEU A  96
 None
 1.17A 5hm8E-1yvdA:
undetectable		 5hm8E-1yvdA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1yvd RAS-RELATED PROTEIN
RAB-22A
(Mus
musculus) 		4 / 5 GLU A 127
THR A  88
GLU A 146
LEU A  96
 None
 1.17A 5hm8F-1yvdA:
undetectable		 5hm8F-1yvdA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1yvd RAS-RELATED PROTEIN
RAB-22A
(Mus
musculus) 		4 / 5 GLU A 127
THR A  88
GLU A 146
LEU A  96
 None
 1.23A 5hm8G-1yvdA:
2.1		 5hm8G-1yvdA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1yvd RAS-RELATED PROTEIN
RAB-22A
(Mus
musculus) 		4 / 5 GLU A 127
THR A  88
GLU A 146
LEU A  96
 None
 1.17A 5hm8H-1yvdA:
2.1		 5hm8H-1yvdA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 1yvd RAS-RELATED PROTEIN
RAB-22A
(Mus
musculus) 		5 / 10 ILE A  83
LEU A 103
ALA A  80
ILE A 111
ILE A 162
 None
 1.00A 5mvmD-1yvdA:
undetectable
5mvmE-1yvdA:
undetectable		 5mvmD-1yvdA:
18.45
5mvmE-1yvdA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 1yvd RAS-RELATED PROTEIN
RAB-22A
(Mus
musculus) 		5 / 12 GLY A 117
ALA A 116
GLY A  12
SER A  20
ILE A  21
 None
None
None
GNP  A 900 (-2.8A)
None
 0.81A 5t2zB-1yvdA:
undetectable		 5t2zB-1yvdA:
19.53