SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yvk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IE9_A_VDXA500_1 (VITAMIN D3 RECEPTOR)	1yvk	HYPOTHETICAL PROTEIN BSU33890 (Bacillus subtilis)	5 / 12	LEU A 21 LEU A 18 CYH A 41 VAL A 71 LEU A 6	None None None COA A 201 (-4.6A) None	1.38A	1ie9A-1yvkA: undetectable	1ie9A-1yvkA: 22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RUK_H_BEZH601_0 (IMMUNOGLOBULIN IGG2A, HEAVY CHAIN IMMUNOGLOBULIN IGG2A, LIGHT CHAIN)	1yvk	HYPOTHETICAL PROTEIN BSU33890 (Bacillus subtilis)	4 / 8	ALA A 25 ASN A 68 LEU A 22 GLY A 52	COA A 201 (-3.6A) None None None	0.83A	1rukH-1yvkA: undetectable 1rukL-1yvkA: undetectable	1rukH-1yvkA: 14.94 1rukL-1yvkA: 18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LTW_A_STRA301_1 (ANCESTRAL STEROID RECEPTOR 2)	1yvk	HYPOTHETICAL PROTEIN BSU33890 (Bacillus subtilis)	5 / 12	LEU A 18 LEU A 21 LEU A 24 ALA A 25 LEU A 84	None None None COA A 201 (-3.6A) None	1.16A	4ltwA-1yvkA: undetectable	4ltwA-1yvkA: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I6X_A_8PRA705_1 (SODIUM-DEPENDENT SEROTONIN TRANSPORTER)	1yvk	HYPOTHETICAL PROTEIN BSU33890 (Bacillus subtilis)	5 / 10	ASP A 87 ALA A 70 ILE A 69 TYR A 54 GLY A 52	None COA A 201 (-3.6A) COA A 201 (-4.5A) None None	1.25A	5i6xA-1yvkA: undetectable	5i6xA-1yvkA: 14.21

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1IE9_A_VDXA500_1","VITAMIN D3 RECEPTOR","1yvk","HYPOTHETICAL PROTEIN BSU33890","Bacillus subtilis",5,"LEU A  21;LEU A  18;CYH A  41;VAL A  71;LEU A   6","None;None;None;COA A 201 (-4.6A);None","1.38A","1ie9A-1yvkA:undetectable","1ie9A-1yvkA:22.91"],["1RUK_H_BEZH601_0","IMMUNOGLOBULIN IGG2A, HEAVY CHAIN;IMMUNOGLOBULIN IGG2A, LIGHT CHAIN","1yvk","HYPOTHETICAL PROTEIN BSU33890","Bacillus subtilis",4,"ALA A  25;ASN A  68;LEU A  22;GLY A  52","COA A 201 (-3.6A);None;None;None","0.83A","1rukH-1yvkA:undetectable;1rukL-1yvkA:undetectable","1rukH-1yvkA:14.94;1rukL-1yvkA:18.67"],["4LTW_A_STRA301_1","ANCESTRAL STEROID RECEPTOR 2","1yvk","HYPOTHETICAL PROTEIN BSU33890","Bacillus subtilis",5,"LEU A  18;LEU A  21;LEU A  24;ALA A  25;LEU A  84","None;None;None;COA A 201 (-3.6A);None","1.16A","4ltwA-1yvkA:undetectable","4ltwA-1yvkA:20.16"],["5I6X_A_8PRA705_1","SODIUM-DEPENDENT SEROTONIN TRANSPORTER","1yvk","HYPOTHETICAL PROTEIN BSU33890","Bacillus subtilis",5,"ASP A  87;ALA A  70;ILE A  69;TYR A  54;GLY A  52","None;COA A 201 (-3.6A);COA A 201 (-4.5A);None;None","1.25A","5i6xA-1yvkA:undetectable","5i6xA-1yvkA:14.21"]]