SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ywq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 1ywq NITROREDUCTASE
FAMILY PROTEIN
(Bacillus
cereus) 		4 / 8 ILE A  67
HIS A  61
LEU A  56
VAL A 160
 None
 0.87A 1fslA-1ywqA:
undetectable		 1fslA-1ywqA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ywq NITROREDUCTASE
FAMILY PROTEIN
(Bacillus
cereus) 		4 / 6 GLN A 150
PHE A  64
LEU A  99
PHE A 101
 None
 1.07A 3ablP-1ywqA:
undetectable
3ablW-1ywqA:
undetectable		 3ablP-1ywqA:
21.40
3ablW-1ywqA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 1ywq NITROREDUCTASE
FAMILY PROTEIN
(Bacillus
cereus) 		3 / 3 TRP A 170
VAL A 136
ARG A  15
 None
 0.69A 3b0wA-1ywqA:
undetectable		 3b0wA-1ywqA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1ywq NITROREDUCTASE
FAMILY PROTEIN
(Bacillus
cereus) 		4 / 8 LEU A  56
LEU A  99
VAL A  54
ILE A 166
 None
 0.95A 4oj4A-1ywqA:
undetectable		 4oj4A-1ywqA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_A_ACTA403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1ywq NITROREDUCTASE
FAMILY PROTEIN
(Bacillus
cereus) 		3 / 3 VAL A 136
LEU A 140
VAL A  35
 None
 0.55A 4wq4A-1ywqA:
undetectable		 4wq4A-1ywqA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ywq NITROREDUCTASE
FAMILY PROTEIN
(Bacillus
cereus) 		4 / 6 GLN A 150
PHE A  64
LEU A  99
PHE A 101
 None
 0.94A 5b1bC-1ywqA:
undetectable
5b1bJ-1ywqA:
undetectable		 5b1bC-1ywqA:
21.40
5b1bJ-1ywqA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 1ywq NITROREDUCTASE
FAMILY PROTEIN
(Bacillus
cereus) 		5 / 12 VAL A  55
VAL A  98
GLY A 144
THR A  22
GLY A  94
 None
 1.03A 6brdC-1ywqA:
undetectable		 6brdC-1ywqA:
18.65