SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yww'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HZN_D_ACTD229_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1yww	HYPOTHETICAL PROTEIN PA4738 (Pseudomonas aeruginosa)	4 / 4	ASP A 26 GLY A 15 LYS A 18 GLU A 19	None	1.42A	3hznD-1ywwA: undetectable	3hznD-1ywwA: 16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MSS_A_STIA1_2 (TYROSINE-PROTEIN KINASE ABL1)	1yww	HYPOTHETICAL PROTEIN PA4738 (Pseudomonas aeruginosa)	4 / 6	VAL A 40 ILE A 6 MET A 1 ARG A 53	None	1.14A	3mssA-1ywwA: undetectable	3mssA-1ywwA: 15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MSS_C_STIC1_2 (TYROSINE-PROTEIN KINASE ABL1)	1yww	HYPOTHETICAL PROTEIN PA4738 (Pseudomonas aeruginosa)	4 / 6	VAL A 40 ILE A 6 MET A 1 ARG A 53	None	1.14A	3mssC-1ywwA: undetectable	3mssC-1ywwA: 15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PYY_B_STIB4_2 (V-ABL ABELSON MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1 ISOFORM B VARIANT)	1yww	HYPOTHETICAL PROTEIN PA4738 (Pseudomonas aeruginosa)	4 / 5	VAL A 40 ILE A 6 MET A 1 ARG A 53	None	1.21A	3pyyB-1ywwA: undetectable	3pyyB-1ywwA: 17.28

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3HZN_D_ACTD229_0","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1yww","HYPOTHETICAL PROTEIN PA4738","Pseudomonas aeruginosa",4,"ASP A  26;GLY A  15;LYS A  18;GLU A  19","None","1.42A","3hznD-1ywwA:undetectable","3hznD-1ywwA:16.51"],["3MSS_A_STIA1_2","TYROSINE-PROTEIN KINASE ABL1","1yww","HYPOTHETICAL PROTEIN PA4738","Pseudomonas aeruginosa",4,"VAL A  40;ILE A   6;MET A   1;ARG A  53","None","1.14A","3mssA-1ywwA:undetectable","3mssA-1ywwA:15.81"],["3MSS_C_STIC1_2","TYROSINE-PROTEIN KINASE ABL1","1yww","HYPOTHETICAL PROTEIN PA4738","Pseudomonas aeruginosa",4,"VAL A  40;ILE A   6;MET A   1;ARG A  53","None","1.14A","3mssC-1ywwA:undetectable","3mssC-1ywwA:15.81"],["3PYY_B_STIB4_2","V-ABL ABELSON MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1 ISOFORM B VARIANT","1yww","HYPOTHETICAL PROTEIN PA4738","Pseudomonas aeruginosa",4,"VAL A  40;ILE A   6;MET A   1;ARG A  53","None","1.21A","3pyyB-1ywwA:undetectable","3pyyB-1ywwA:17.28"]]