SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yx0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 1yx0 HYPOTHETICAL PROTEIN
YSNE
(Bacillus
subtilis) 		4 / 5 TYR A 131
MET A 147
THR A 148
LEU A 109
 None
 1.33A 3ag1J-1yx0A:
undetectable		 3ag1J-1yx0A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 1yx0 HYPOTHETICAL PROTEIN
YSNE
(Bacillus
subtilis) 		4 / 5 GLY A 112
SER A 113
PHE A 117
GLU A 118
 None
 1.06A 4m93B-1yx0A:
undetectable
4m93C-1yx0A:
undetectable		 4m93B-1yx0A:
19.20
4m93C-1yx0A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1yx0 HYPOTHETICAL PROTEIN
YSNE
(Bacillus
subtilis) 		4 / 5 TYR A 131
MET A 147
THR A 148
LEU A 109
 None
 1.32A 5w97J-1yx0A:
undetectable		 5w97J-1yx0A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1yx0 HYPOTHETICAL PROTEIN
YSNE
(Bacillus
subtilis) 		4 / 5 TYR A 131
MET A 147
THR A 148
LEU A 109
 None
 1.35A 5wauJ-1yx0A:
undetectable		 5wauJ-1yx0A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1yx0 HYPOTHETICAL PROTEIN
YSNE
(Bacillus
subtilis) 		4 / 5 TYR A 131
MET A 147
THR A 148
LEU A 109
 None
 1.35A 5x19J-1yx0A:
undetectable		 5x19J-1yx0A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1yx0 HYPOTHETICAL PROTEIN
YSNE
(Bacillus
subtilis) 		4 / 5 TYR A 131
MET A 147
THR A 148
LEU A 109
 None
 1.29A 5x1bJ-1yx0A:
undetectable		 5x1bJ-1yx0A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1yx0 HYPOTHETICAL PROTEIN
YSNE
(Bacillus
subtilis) 		4 / 5 TYR A 131
MET A 147
THR A 148
LEU A 109
 None
 1.25A 5x1bW-1yx0A:
undetectable		 5x1bW-1yx0A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1yx0 HYPOTHETICAL PROTEIN
YSNE
(Bacillus
subtilis) 		4 / 5 TYR A 131
MET A 147
THR A 148
LEU A 109
 None
 1.28A 5x1fW-1yx0A:
undetectable		 5x1fW-1yx0A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 1yx0 HYPOTHETICAL PROTEIN
YSNE
(Bacillus
subtilis) 		4 / 8 GLY A  86
THR A  78
PHE A 127
TYR A 124
 None
 0.80A 6eqpA-1yx0A:
undetectable		 6eqpA-1yx0A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1yx0 HYPOTHETICAL PROTEIN
YSNE
(Bacillus
subtilis) 		4 / 5 TYR A 131
MET A 147
THR A 148
LEU A 109
 None
 1.34A 6nknJ-1yx0A:
undetectable		 6nknJ-1yx0A:
19.33