SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yx2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_1
(PROTEIN (HIV-1
PROTEASE))		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 10 ALA A 161
ASP A 160
ASP A 176
ILE A 177
PHE A 171
 None
 1.17A 1d4sA-1yx2A:
undetectable		 1d4sA-1yx2A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 12 ALA A 258
LEU A 244
ILE A 237
ARG A 232
THR A  71
 None
 1.16A 1jolA-1yx2A:
undetectable		 1jolA-1yx2A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_2
(ADENOSINE KINASE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		4 / 4 SER A 185
LEU A  99
TYR A 198
GLY A 188
 None
 1.45A 1liiA-1yx2A:
undetectable		 1liiA-1yx2A:
25.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_0
(N,N-DIMETHYLGLYCINE
OXIDASE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		6 / 12 TYR A  84
ASN A 113
PHE A 169
TYR A 189
TYR A 198
PHE A 257
 None
 0.82A 1pj7A-1yx2A:
43.8		 1pj7A-1yx2A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		4 / 6 ARG A 283
ASP A 120
ASN A 116
GLU A 252
 None
 1.30A 1rjdB-1yx2A:
undetectable		 1rjdB-1yx2A:
21.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WOP_A_FFOA2887_0
(AMINOMETHYLTRANSFERA
SE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		6 / 12 MET A  52
TYR A  84
TYR A 101
VAL A 111
ASN A 113
TYR A 189
 None
 0.46A 1wopA-1yx2A:
48.9		 1wopA-1yx2A:
45.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		4 / 5 ILE A 154
SER A 185
ARG A 186
LEU A 155
 None
 1.17A 1y0xX-1yx2A:
undetectable		 1y0xX-1yx2A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		4 / 6 LEU A 109
MET A  70
LEU A  98
ILE A 141
 None
 0.99A 1z95A-1yx2A:
undetectable		 1z95A-1yx2A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		4 / 6 THR A 187
LEU A  99
VAL A 111
VAL A  49
 None
 0.99A 2z97A-1yx2A:
undetectable		 2z97A-1yx2A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		4 / 6 THR A 187
LEU A  99
VAL A 111
VAL A  49
 None
 1.07A 2zuhA-1yx2A:
0.0		 2zuhA-1yx2A:
24.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A8I_A_C2FA401_0
(AMINOMETHYLTRANSFERA
SE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 12 MET A  52
ASP A  96
TYR A 101
VAL A 111
ASN A 113
 None
 1.44A 3a8iA-1yx2A:
44.4		 3a8iA-1yx2A:
40.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A8I_A_C2FA401_0
(AMINOMETHYLTRANSFERA
SE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		7 / 12 MET A  52
TYR A  84
ASP A  97
TYR A 101
VAL A 111
ASN A 113
TYR A 189
 None
 0.58A 3a8iA-1yx2A:
44.4		 3a8iA-1yx2A:
40.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A8I_A_C2FA401_0
(AMINOMETHYLTRANSFERA
SE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 12 TYR A  84
ASP A  97
ASN A 113
TYR A 189
ARG A 228
 None
 1.39A 3a8iA-1yx2A:
44.4		 3a8iA-1yx2A:
40.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A8I_A_C2FA401_0
(AMINOMETHYLTRANSFERA
SE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		7 / 12 TYR A  84
ASP A  97
TYR A 101
VAL A 111
ASN A 113
PHE A 169
TYR A 189
 None
 0.48A 3a8iA-1yx2A:
44.4		 3a8iA-1yx2A:
40.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A8I_B_C2FB401_0
(AMINOMETHYLTRANSFERA
SE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 12 MET A  52
ASP A  96
TYR A 101
VAL A 111
ASN A 113
 None
 1.44A 3a8iB-1yx2A:
43.7		 3a8iB-1yx2A:
40.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A8I_B_C2FB401_0
(AMINOMETHYLTRANSFERA
SE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		7 / 12 MET A  52
TYR A  84
ASP A  97
TYR A 101
VAL A 111
ASN A 113
TYR A 189
 None
 0.59A 3a8iB-1yx2A:
43.7		 3a8iB-1yx2A:
40.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A8I_B_C2FB401_0
(AMINOMETHYLTRANSFERA
SE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 12 TYR A  84
ASP A  97
ASN A 113
TYR A 189
ARG A 228
 None
 1.42A 3a8iB-1yx2A:
43.7		 3a8iB-1yx2A:
40.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A8I_B_C2FB401_0
(AMINOMETHYLTRANSFERA
SE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		7 / 12 TYR A  84
ASP A  97
TYR A 101
VAL A 111
ASN A 113
PHE A 169
TYR A 189
 None
 0.55A 3a8iB-1yx2A:
43.7		 3a8iB-1yx2A:
40.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A8I_C_C2FC401_0
(AMINOMETHYLTRANSFERA
SE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		7 / 12 MET A  52
TYR A  84
TYR A 101
VAL A 111
ASN A 113
PHE A 169
TYR A 189
 None
 0.66A 3a8iC-1yx2A:
44.5		 3a8iC-1yx2A:
40.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A8I_C_C2FC401_0
(AMINOMETHYLTRANSFERA
SE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		7 / 12 TYR A  84
TYR A 101
VAL A 111
ASN A 113
PHE A 169
THR A 187
TYR A 189
 None
 0.59A 3a8iC-1yx2A:
44.5		 3a8iC-1yx2A:
40.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A8I_D_C2FD401_0
(AMINOMETHYLTRANSFERA
SE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 12 MET A  52
ASP A  96
TYR A 101
VAL A 111
ASN A 113
 None
 1.42A 3a8iD-1yx2A:
44.6		 3a8iD-1yx2A:
40.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A8I_D_C2FD401_0
(AMINOMETHYLTRANSFERA
SE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		7 / 12 MET A  52
TYR A  84
ASP A  97
TYR A 101
VAL A 111
ASN A 113
TYR A 189
 None
 0.59A 3a8iD-1yx2A:
44.6		 3a8iD-1yx2A:
40.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A8I_D_C2FD401_0
(AMINOMETHYLTRANSFERA
SE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 12 TYR A  84
ASP A  97
ASN A 113
TYR A 189
ARG A 228
 None
 1.31A 3a8iD-1yx2A:
44.6		 3a8iD-1yx2A:
40.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A8I_D_C2FD401_0
(AMINOMETHYLTRANSFERA
SE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		7 / 12 TYR A  84
ASP A  97
TYR A 101
VAL A 111
ASN A 113
PHE A 169
TYR A 189
 None
 0.48A 3a8iD-1yx2A:
44.6		 3a8iD-1yx2A:
40.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		4 / 6 LEU A 158
SER A 178
ILE A 197
CYH A 199
 None
 0.95A 3ko0S-1yx2A:
undetectable		 3ko0S-1yx2A:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		4 / 8 ILE A 255
PRO A 250
GLY A 256
ASN A  72
 None
 0.92A 3lslA-1yx2A:
undetectable
3lslD-1yx2A:
undetectable		 3lslA-1yx2A:
22.88
3lslD-1yx2A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		4 / 8 ASN A  72
ILE A 255
PRO A 250
GLY A 256
 None
 0.89A 3lslA-1yx2A:
undetectable
3lslD-1yx2A:
undetectable		 3lslA-1yx2A:
22.88
3lslD-1yx2A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA302_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		4 / 6 LEU A 239
GLU A 243
PRO A 238
HIS A 298
 None
 1.41A 3ltwA-1yx2A:
undetectable		 3ltwA-1yx2A:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		4 / 6 VAL A 111
ASN A 113
TYR A 198
GLU A 196
 None
 0.78A 3q5sA-1yx2A:
undetectable		 3q5sA-1yx2A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 12 LYS A 156
LEU A 158
ASN A 157
ALA A  44
ILE A 211
 None
 1.18A 3ut5D-1yx2A:
undetectable		 3ut5D-1yx2A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 10 GLY A 287
ALA A 352
GLU A 289
MET A 290
VAL A 286
 None
 1.22A 4da7A-1yx2A:
undetectable		 4da7A-1yx2A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		4 / 7 TYR A 198
ILE A 207
ILE A 177
ALA A 182
 None
 0.88A 4lv9A-1yx2A:
undetectable		 4lv9A-1yx2A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 12 ILE A 184
ALA A 161
LEU A 166
ALA A 165
ILE A 211
 None
 1.06A 4nqaH-1yx2A:
undetectable		 4nqaH-1yx2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		4 / 7 LEU A 109
MET A  70
LEU A  98
ILE A 141
 None
 0.91A 4okwA-1yx2A:
undetectable		 4okwA-1yx2A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 12 ALA A 114
SER A 115
GLY A  22
PHE A  21
TYR A 189
 None
 1.21A 4r29A-1yx2A:
undetectable		 4r29A-1yx2A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 12 ALA A 114
SER A 115
GLY A  22
PHE A  21
TYR A 189
 None
 1.19A 4r29B-1yx2A:
undetectable		 4r29B-1yx2A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 12 ALA A 114
SER A 115
GLY A  22
PHE A  21
TYR A 189
 None
 1.23A 4r29C-1yx2A:
undetectable		 4r29C-1yx2A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI2_A_BAXA801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 8 ILE A 197
VAL A  57
ILE A 112
ILE A 134
ILE A 117
 None
 1.47A 5hi2A-1yx2A:
undetectable		 5hi2A-1yx2A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_B_ESTB601_1
(ESTROGEN RECEPTOR)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 11 LEU A  77
ALA A  82
LEU A  99
LEU A 110
LEU A 183
 None
 1.39A 5hyrB-1yx2A:
undetectable		 5hyrB-1yx2A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		4 / 6 THR A  85
ASP A  97
LEU A  98
ASP A 120
 None
 1.02A 5tdzA-1yx2A:
undetectable		 5tdzA-1yx2A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 7 LEU A 158
LEU A 143
ILE A 154
GLY A 215
LEU A 220
 None
 1.20A 5vkqA-1yx2A:
undetectable
5vkqB-1yx2A:
undetectable		 5vkqA-1yx2A:
12.20
5vkqB-1yx2A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 8 LEU A 158
LEU A 143
ILE A 154
GLY A 215
LEU A 220
 None
 1.21A 5vkqB-1yx2A:
undetectable
5vkqC-1yx2A:
undetectable		 5vkqB-1yx2A:
12.20
5vkqC-1yx2A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		4 / 8 ILE A 112
TYR A  84
VAL A  95
ASP A 118
 None
 1.09A 5vlmF-1yx2A:
undetectable		 5vlmF-1yx2A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 9 SER A 318
THR A 316
GLY A 326
LEU A 327
GLU A 289
 None
 1.25A 5vw4A-1yx2A:
undetectable		 5vw4A-1yx2A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		4 / 5 PRO A 296
VAL A 312
GLY A 306
VAL A 341
 None
 1.12A 6ak3B-1yx2A:
undetectable		 6ak3B-1yx2A:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 12 GLY A 226
LEU A 225
HIS A  51
ARG A 232
GLN A 242
 None
 1.09A 6gngB-1yx2A:
undetectable		 6gngB-1yx2A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		4 / 6 TYR A 195
ILE A 184
ALA A 165
ARG A 186
 None
 1.15A 6hu9m-1yx2A:
undetectable
6hu9q-1yx2A:
undetectable		 6hu9m-1yx2A:
21.97
6hu9q-1yx2A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN8_A_HFGA603_0
(UNCHARACTERIZED
PROTEIN)		 1yx2 AMINOMETHYLTRANSFERA
SE
(Bacillus
subtilis) 		5 / 12 LEU A 288
GLU A 301
VAL A 343
THR A 245
GLY A 241
 None
 1.25A 6mn8A-1yx2A:
undetectable		 6mn8A-1yx2A:
20.87