SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yx3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RKG_B_AB1B501_2 (PROTEASE RETROPEPSIN)	1yx3	HYPOTHETICAL PROTEIN DSRC (Allochromatium vinosum)	5 / 12	ASP A 48 ILE A 49 VAL A 73 GLY A 82 PRO A 95	None	0.92A	2rkgB-1yx3A: undetectable	2rkgB-1yx3A: 20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QWP_A_GCSA301_1 (CHITOSANASE)	1yx3	HYPOTHETICAL PROTEIN DSRC (Allochromatium vinosum)	3 / 3	TYR A 88 GLY A 94 PRO A 95	None	0.64A	4qwpA-1yx3A: undetectable	4qwpA-1yx3A: 19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DBY_A_ACTA610_0 (SERUM ALBUMIN)	1yx3	HYPOTHETICAL PROTEIN DSRC (Allochromatium vinosum)	3 / 3	TYR A 19 LYS A 97 LYS A 107	None	1.23A	5dbyA-1yx3A: undetectable	5dbyA-1yx3A: 12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OF1_A_SALA301_1 (SPORE COAT-ASSOCIATED PROTEIN N)	1yx3	HYPOTHETICAL PROTEIN DSRC (Allochromatium vinosum)	4 / 5	ALA A 72 VAL A 68 PHE A 52 ILE A 62	None	0.90A	5of1A-1yx3A: undetectable	5of1A-1yx3A: 22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A7P_A_9SCA601_0 (SERUM ALBUMIN)	1yx3	HYPOTHETICAL PROTEIN DSRC (Allochromatium vinosum)	5 / 12	LEU A 23 VAL A 73 LEU A 87 GLY A 18 ARG A 54	None	1.09A	6a7pA-1yx3A: undetectable	6a7pA-1yx3A: 12.15

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2RKG_B_AB1B501_2","PROTEASE RETROPEPSIN","1yx3","HYPOTHETICAL PROTEIN DSRC","Allochromatium vinosum",5,"ASP A  48;ILE A  49;VAL A  73;GLY A  82;PRO A  95","None","0.92A","2rkgB-1yx3A:undetectable","2rkgB-1yx3A:20.83"],["4QWP_A_GCSA301_1","CHITOSANASE","1yx3","HYPOTHETICAL PROTEIN DSRC","Allochromatium vinosum",3,"TYR A  88;GLY A  94;PRO A  95","None","0.64A","4qwpA-1yx3A:undetectable","4qwpA-1yx3A:19.58"],["5DBY_A_ACTA610_0","SERUM ALBUMIN","1yx3","HYPOTHETICAL PROTEIN DSRC","Allochromatium vinosum",3,"TYR A  19;LYS A  97;LYS A 107","None","1.23A","5dbyA-1yx3A:undetectable","5dbyA-1yx3A:12.70"],["5OF1_A_SALA301_1","SPORE COAT-ASSOCIATED PROTEIN N","1yx3","HYPOTHETICAL PROTEIN DSRC","Allochromatium vinosum",4,"ALA A  72;VAL A  68;PHE A  52;ILE A  62","None","0.90A","5of1A-1yx3A:undetectable","5of1A-1yx3A:22.58"],["6A7P_A_9SCA601_0","SERUM ALBUMIN","1yx3","HYPOTHETICAL PROTEIN DSRC","Allochromatium vinosum",5,"LEU A  23;VAL A  73;LEU A  87;GLY A  18;ARG A  54","None","1.09A","6a7pA-1yx3A:undetectable","6a7pA-1yx3A:12.15"]]