SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yxb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IWI_A_CAMA418_0 (CYTOCHROME P450-CAM)	1yxb	PHOSPHORIBOSYL-ATP PYROPHOSPHATASE (Streptomyces coelicolor)	4 / 8	PHE A 6 LEU A 90 VAL A 86 VAL A 72	None	0.96A	1iwiA-1yxbA: undetectable	1iwiA-1yxbA: 11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MZ9_A_VDYA1002_2 (CARTILAGE OLIGOMERIC MATRIX PROTEIN)	1yxb	PHOSPHORIBOSYL-ATP PYROPHOSPHATASE (Streptomyces coelicolor)	3 / 3	ILE A 65 LEU A 68 VAL A 72	None	0.19A	1mz9B-1yxbA: undetectable	1mz9B-1yxbA: 25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L4B_A_CAMA502_0 (CAMPHOR 5-MONOOXYGENASE)	1yxb	PHOSPHORIBOSYL-ATP PYROPHOSPHATASE (Streptomyces coelicolor)	4 / 8	PHE A 6 LEU A 90 VAL A 86 VAL A 72	None	0.97A	4l4bA-1yxbA: undetectable	4l4bA-1yxbA: 11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CP4_A_CAMA422_0 (CYTOCHROME P450CAM)	1yxb	PHOSPHORIBOSYL-ATP PYROPHOSPHATASE (Streptomyces coelicolor)	4 / 8	PHE A 6 LEU A 90 VAL A 86 VAL A 72	None	0.96A	6cp4A-1yxbA: undetectable	6cp4A-1yxbA: 12.76

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1IWI_A_CAMA418_0","CYTOCHROME P450-CAM","1yxb","PHOSPHORIBOSYL-ATP PYROPHOSPHATASE","Streptomyces coelicolor",4,"PHE A   6;LEU A  90;VAL A  86;VAL A  72","None","0.96A","1iwiA-1yxbA:undetectable","1iwiA-1yxbA:11.17"],["1MZ9_A_VDYA1002_2","CARTILAGE OLIGOMERIC MATRIX PROTEIN;CARTILAGE OLIGOMERIC MATRIX PROTEIN","1yxb","PHOSPHORIBOSYL-ATP PYROPHOSPHATASE","Streptomyces coelicolor",3,"ILE A  65;LEU A  68;VAL A  72","None","0.19A","1mz9B-1yxbA:undetectable","1mz9B-1yxbA:25.40"],["4L4B_A_CAMA502_0","CAMPHOR 5-MONOOXYGENASE","1yxb","PHOSPHORIBOSYL-ATP PYROPHOSPHATASE","Streptomyces coelicolor",4,"PHE A   6;LEU A  90;VAL A  86;VAL A  72","None","0.97A","4l4bA-1yxbA:undetectable","4l4bA-1yxbA:11.65"],["6CP4_A_CAMA422_0","CYTOCHROME P450CAM","1yxb","PHOSPHORIBOSYL-ATP PYROPHOSPHATASE","Streptomyces coelicolor",4,"PHE A   6;LEU A  90;VAL A  86;VAL A  72","None","0.96A","6cp4A-1yxbA:undetectable","6cp4A-1yxbA:12.76"]]