SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yy7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1yy7 STRINGENT STARVATION
PROTEIN A
(Yersinia
pestis) 		4 / 7 PHE A 149
LEU A 168
PHE A 143
SER A 138
 None
 1.02A 1wrlE-1yy7A:
undetectable		 1wrlE-1yy7A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 1yy7 STRINGENT STARVATION
PROTEIN A
(Yersinia
pestis) 		4 / 8 GLY A  16
ARG A 167
GLN A  40
THR A 201
 None
 0.91A 3rglA-1yy7A:
undetectable		 3rglA-1yy7A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 1yy7 STRINGENT STARVATION
PROTEIN A
(Yersinia
pestis) 		3 / 3 GLN A  24
PHE A  21
TYR A 111
 None
 0.70A 3ucjB-1yy7A:
undetectable		 3ucjB-1yy7A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 1yy7 STRINGENT STARVATION
PROTEIN A
(Yersinia
pestis) 		3 / 3 GLN A  24
PHE A  21
TYR A 111
 None
 0.75A 3ucjA-1yy7A:
undetectable		 3ucjA-1yy7A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1yy7 STRINGENT STARVATION
PROTEIN A
(Yersinia
pestis) 		4 / 6 PHE A 149
PHE A 143
LEU A 183
PHE A 175
 None
 1.12A 5z84P-1yy7A:
2.3
5z84W-1yy7A:
undetectable		 5z84P-1yy7A:
20.74
5z84W-1yy7A:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1yy7 STRINGENT STARVATION
PROTEIN A
(Yersinia
pestis) 		4 / 6 PHE A 149
PHE A 143
LEU A 183
PHE A 175
 None
 1.14A 5z85P-1yy7A:
2.3
5z85W-1yy7A:
undetectable		 5z85P-1yy7A:
20.74
5z85W-1yy7A:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1yy7 STRINGENT STARVATION
PROTEIN A
(Yersinia
pestis) 		4 / 6 PHE A 149
PHE A 143
LEU A 183
PHE A 175
 None
 1.09A 5z86P-1yy7A:
2.3
5z86W-1yy7A:
undetectable		 5z86P-1yy7A:
20.74
5z86W-1yy7A:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 1yy7 STRINGENT STARVATION
PROTEIN A
(Yersinia
pestis) 		4 / 5 TYR A 115
GLN A 119
GLY A  16
ILE A  20
 None
 1.32A 6debB-1yy7A:
undetectable		 6debB-1yy7A:
16.50